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The Yin-Yang of TCF/beta-catenin signaling.
Barker N, Morin PJ, Clevers H. Barker N, et al. Adv Cancer Res. 2000;77:1-24. doi: 10.1016/s0065-230x(08)60783-6. Adv Cancer Res. 2000. PMID: 10549354 Review.
There is also a concomitant translocation of beta-catenin/Armadillo to the nucleus, where it interacts with a specific sequence motif at the N terminus of Tcfs to generate a transcriptionally active complex. ...A proportion of APC wild-type colon carcinomas and melanomas a …
There is also a concomitant translocation of beta-catenin/Armadillo to the nucleus, where it interacts with a specific sequence motif at the …
The role of APC and beta-catenin in the aetiology of aggressive fibromatosis (desmoid tumors).
Lips DJ, Barker N, Clevers H, Hennipman A. Lips DJ, et al. Among authors: barker n. Eur J Surg Oncol. 2009 Jan;35(1):3-10. doi: 10.1016/j.ejso.2008.07.003. Epub 2008 Aug 21. Eur J Surg Oncol. 2009. PMID: 18722078 Review.
Mutant E-cadherin breast cancer cells do not display constitutive Wnt signaling.
van de Wetering M, Barker N, Harkes IC, van der Heyden M, Dijk NJ, Hollestelle A, Klijn JG, Clevers H, Schutte M. van de Wetering M, et al. Among authors: barker n. Cancer Res. 2001 Jan 1;61(1):278-84. Cancer Res. 2001. PMID: 11196175
Two members of the Tcf family implicated in Wnt/beta-catenin signaling during embryogenesis in the mouse.
Korinek V, Barker N, Willert K, Molenaar M, Roose J, Wagenaar G, Markman M, Lamers W, Destree O, Clevers H. Korinek V, et al. Among authors: barker n. Mol Cell Biol. 1998 Mar;18(3):1248-56. doi: 10.1128/mcb.18.3.1248. Mol Cell Biol. 1998. PMID: 9488439 Free PMC article.
The chromatin remodelling factor Brg-1 interacts with beta-catenin to promote target gene activation.
Barker N, Hurlstone A, Musisi H, Miles A, Bienz M, Clevers H. Barker N, et al. EMBO J. 2001 Sep 3;20(17):4935-43. doi: 10.1093/emboj/20.17.4935. EMBO J. 2001. PMID: 11532957 Free PMC article.
Catenins, Wnt signaling and cancer.
Barker N, Clevers H. Barker N, et al. Bioessays. 2000 Nov;22(11):961-5. doi: 10.1002/1521-1878(200011)22:11<961::AID-BIES1>3.0.CO;2-T. Bioessays. 2000. PMID: 11056471 Review.
The TAK1-NLK-MAPK-related pathway antagonizes signalling between beta-catenin and transcription factor TCF.
Ishitani T, Ninomiya-Tsuji J, Nagai S, Nishita M, Meneghini M, Barker N, Waterman M, Bowerman B, Clevers H, Shibuya H, Matsumoto K. Ishitani T, et al. Among authors: barker n. Nature. 1999 Jun 24;399(6738):798-802. doi: 10.1038/21674. Nature. 1999. PMID: 10391247
Restricted high level expression of Tcf-4 protein in intestinal and mammary gland epithelium.
Barker N, Huls G, Korinek V, Clevers H. Barker N, et al. Am J Pathol. 1999 Jan;154(1):29-35. doi: 10.1016/S0002-9440(10)65247-9. Am J Pathol. 1999. PMID: 9916915 Free PMC article.
Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4.
Korinek V, Barker N, Moerer P, van Donselaar E, Huls G, Peters PJ, Clevers H. Korinek V, et al. Among authors: barker n. Nat Genet. 1998 Aug;19(4):379-83. doi: 10.1038/1270. Nat Genet. 1998. PMID: 9697701
Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma.
Korinek V, Barker N, Morin PJ, van Wichen D, de Weger R, Kinzler KW, Vogelstein B, Clevers H. Korinek V, et al. Among authors: barker n. Science. 1997 Mar 21;275(5307):1784-7. doi: 10.1126/science.275.5307.1784. Science. 1997. PMID: 9065401
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