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Mining the Wnt pathway for cancer therapeutics.
Barker N, Clevers H. Barker N, et al. Nat Rev Drug Discov. 2006 Dec;5(12):997-1014. doi: 10.1038/nrd2154. Nat Rev Drug Discov. 2006. PMID: 17139285 Review.
The intestinal stem cell.
Barker N, van de Wetering M, Clevers H. Barker N, et al. Genes Dev. 2008 Jul 15;22(14):1856-64. doi: 10.1101/gad.1674008. Genes Dev. 2008. PMID: 18628392 Free PMC article. Review.
Crypt stem cells as the cells-of-origin of intestinal cancer.
Barker N, Ridgway RA, van Es JH, van de Wetering M, Begthel H, van den Born M, Danenberg E, Clarke AR, Sansom OJ, Clevers H. Barker N, et al. Nature. 2009 Jan 29;457(7229):608-11. doi: 10.1038/nature07602. Epub 2008 Dec 17. Nature. 2009. PMID: 19092804
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