Barkovich KJ - Search Results

1

Analog sensitive chemical inhibition of the DEAD-box protein DDX3.

Floor SN, Barkovich KJ, Condon KJ, Shokat KM, Doudna JA. Floor SN, et al. Among authors: barkovich kj. Protein Sci. 2016 Mar;25(3):638-49. doi: 10.1002/pro.2857. Epub 2015 Dec 26. Protein Sci. 2016. PMID: 26650549 Free PMC article.

2

Chemical genetic inhibition of DEAD-box proteins using covalent complementarity.

Barkovich KJ, Moore MK, Hu Q, Shokat KM. Barkovich KJ, et al. Nucleic Acids Res. 2018 Sep 28;46(17):8689-8699. doi: 10.1093/nar/gky706. Nucleic Acids Res. 2018. PMID: 30102385 Free PMC article.

3

Type II Kinase Inhibitors Targeting Cys-Gatekeeper Kinases Display Orthogonality with Wild Type and Ala/Gly-Gatekeeper Kinases.

Ocasio CA, Warkentin AA, McIntyre PJ, Barkovich KJ, Vesely C, Spencer J, Shokat KM, Bayliss R. Ocasio CA, et al. Among authors: barkovich kj. ACS Chem Biol. 2018 Oct 19;13(10):2956-2965. doi: 10.1021/acschembio.8b00592. Epub 2018 Oct 9. ACS Chem Biol. 2018. PMID: 30239186 Free article.

4

p27 allosterically activates cyclin-dependent kinase 4 and antagonizes palbociclib inhibition.

Guiley KZ, Stevenson JW, Lou K, Barkovich KJ, Kumarasamy V, Wijeratne TU, Bunch KL, Tripathi S, Knudsen ES, Witkiewicz AK, Shokat KM, Rubin SM. Guiley KZ, et al. Among authors: barkovich kj. Science. 2019 Dec 13;366(6471):eaaw2106. doi: 10.1126/science.aaw2106. Science. 2019. PMID: 31831640 Free PMC article.

5

Kinetics of inhibitor cycling underlie therapeutic disparities between EGFR-driven lung and brain cancers.

Barkovich KJ, Hariono S, Garske AL, Zhang J, Blair JA, Fan QW, Shokat KM, Nicolaides T, Weiss WA. Barkovich KJ, et al. Cancer Discov. 2012 May;2(5):450-7. doi: 10.1158/2159-8290.CD-11-0287. Epub 2012 Mar 31. Cancer Discov. 2012. PMID: 22588882 Free PMC article.

6

Targeted therapy for BRAFV600E malignant astrocytoma.

Nicolaides TP, Li H, Solomon DA, Hariono S, Hashizume R, Barkovich K, Baker SJ, Paugh BS, Jones C, Forshew T, Hindley GF, Hodgson JG, Kim JS, Rowitch DH, Weiss WA, Waldman TA, James CD. Nicolaides TP, et al. Clin Cancer Res. 2011 Dec 15;17(24):7595-604. doi: 10.1158/1078-0432.CCR-11-1456. Epub 2011 Oct 28. Clin Cancer Res. 2011. PMID: 22038996 Free PMC article.

7

Kinase Atlas: Druggability Analysis of Potential Allosteric Sites in Kinases.

Yueh C, Rettenmaier J, Xia B, Hall DR, Alekseenko A, Porter KA, Barkovich K, Keseru G, Whitty A, Wells JA, Vajda S, Kozakov D. Yueh C, et al. J Med Chem. 2019 Jul 25;62(14):6512-6524. doi: 10.1021/acs.jmedchem.9b00089. Epub 2019 Jul 5. J Med Chem. 2019. PMID: 31274316 Free PMC article. Review.

8

Combined BRAF^V600E and MEK blockade for BRAF^V600E-mutant gliomas.

Zhang J, Yao TW, Hashizume R, Hariono S, Barkovich KJ, Fan QW, Prados M, James CD, Weiss WA, Nicolaides T. Zhang J, et al. Among authors: barkovich kj. J Neurooncol. 2017 Feb;131(3):495-505. doi: 10.1007/s11060-016-2333-4. Epub 2016 Nov 15. J Neurooncol. 2017. PMID: 27848137 Free PMC article.

9

iRGD-targeted Physalis Mottle Virus-like Nanoparticles for Targeted Cancer Delivery.

Barkovich KJ, Zhao Z, Steinmetz NF. Barkovich KJ, et al. Small Sci. 2023 Aug;3(8):2300067. doi: 10.1002/smsc.202300067. Epub 2023 Jun 27. Small Sci. 2023. PMID: 38465197

10

Virus-like Particles Armored by an Endoskeleton.

Wu Z, Bayón JL, Kouznetsova TB, Ouchi T, Barkovich KJ, Hsu SK, Craig SL, Steinmetz NF. Wu Z, et al. Among authors: barkovich kj. Nano Lett. 2024 Mar 13;24(10):2989-2997. doi: 10.1021/acs.nanolett.3c03806. Epub 2024 Jan 31. Nano Lett. 2024. PMID: 38294951

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