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Musashi2 sustains the mixed-lineage leukemia-driven stem cell regulatory program.
Park SM, Gönen M, Vu L, Minuesa G, Tivnan P, Barlowe TS, Taggart J, Lu Y, Deering RP, Hacohen N, Figueroa ME, Paietta E, Fernandez HF, Tallman MS, Melnick A, Levine R, Leslie C, Lengner CJ, Kharas MG. Park SM, et al. Among authors: barlowe ts. J Clin Invest. 2015 Mar 2;125(3):1286-98. doi: 10.1172/JCI78440. Epub 2015 Feb 9. J Clin Invest. 2015. PMID: 25664853 Free PMC article.
MSI2 is required for maintaining activated myelodysplastic syndrome stem cells.
Taggart J, Ho TC, Amin E, Xu H, Barlowe TS, Perez AR, Durham BH, Tivnan P, Okabe R, Chow A, Vu L, Park SM, Prieto C, Famulare C, Patel M, Lengner CJ, Verma A, Roboz G, Guzman M, Klimek VM, Abdel-Wahab O, Leslie C, Nimer SD, Kharas MG. Taggart J, et al. Among authors: barlowe ts. Nat Commun. 2016 Feb 22;7:10739. doi: 10.1038/ncomms10739. Nat Commun. 2016. PMID: 26898884 Free PMC article.
Functional screen of MSI2 interactors identifies an essential role for SYNCRIP in myeloid leukemia stem cells.
Vu LP, Prieto C, Amin EM, Chhangawala S, Krivtsov A, Calvo-Vidal MN, Chou T, Chow A, Minuesa G, Park SM, Barlowe TS, Taggart J, Tivnan P, Deering RP, Chu LP, Kwon JA, Meydan C, Perales-Paton J, Arshi A, Gönen M, Famulare C, Patel M, Paietta E, Tallman MS, Lu Y, Glass J, Garret-Bakelman FE, Melnick A, Levine R, Al-Shahrour F, Järås M, Hacohen N, Hwang A, Garippa R, Lengner CJ, Armstrong SA, Cerchietti L, Cowley GS, Root D, Doench J, Leslie C, Ebert BL, Kharas MG. Vu LP, et al. Among authors: barlowe ts. Nat Genet. 2017 Jun;49(6):866-875. doi: 10.1038/ng.3854. Epub 2017 Apr 24. Nat Genet. 2017. PMID: 28436985 Free PMC article.
IKZF2 Drives Leukemia Stem Cell Self-Renewal and Inhibits Myeloid Differentiation.
Park SM, Cho H, Thornton AM, Barlowe TS, Chou T, Chhangawala S, Fairchild L, Taggart J, Chow A, Schurer A, Gruet A, Witkin MD, Kim JH, Shevach EM, Krivtsov A, Armstrong SA, Leslie C, Kharas MG. Park SM, et al. Among authors: barlowe ts. Cell Stem Cell. 2019 Jan 3;24(1):153-165.e7. doi: 10.1016/j.stem.2018.10.016. Epub 2018 Nov 21. Cell Stem Cell. 2019. PMID: 30472158 Free PMC article.
Transcriptional control of CBX5 by the RNA binding proteins RBMX and RBMXL1 maintains chromatin state in myeloid leukemia.
Prieto C, Nguyen DTT, Liu Z, Wheat J, Perez A, Gourkanti S, Chou T, Barin E, Velleca A, Rohwetter T, Chow A, Taggart J, Savino AM, Hoskova K, Dhodapkar M, Schurer A, Barlowe TS, Vu LP, Leslie C, Steidl U, Rabadan R, Kharas MG. Prieto C, et al. Among authors: barlowe ts. Nat Cancer. 2021 Jul;2:741-757. doi: 10.1038/s43018-021-00220-w. Epub 2021 Jul 5. Nat Cancer. 2021. PMID: 34458856 Free PMC article.
The Msi Family of RNA-Binding Proteins Function Redundantly as Intestinal Oncoproteins.
Li N, Yousefi M, Nakauka-Ddamba A, Li F, Vandivier L, Parada K, Woo DH, Wang S, Naqvi AS, Rao S, Tobias J, Cedeno RJ, Minuesa G, Y K, Barlowe TS, Valvezan A, Shankar S, Deering RP, Klein PS, Jensen ST, Kharas MG, Gregory BD, Yu Z, Lengner CJ. Li N, et al. Among authors: barlowe ts. Cell Rep. 2015 Dec 22;13(11):2440-2455. doi: 10.1016/j.celrep.2015.11.022. Epub 2015 Dec 8. Cell Rep. 2015. PMID: 26673327 Free PMC article.
A woman presenting with an unusual cause of fulminant liver failure and sepsis.
Valtis YK, Barlowe T, Young JH, Lichtman AH, Zhao L, Hornick JL, Cleary JM, Hashemi N, Cubre A, Baron RM. Valtis YK, et al. Clin Res Hepatol Gastroenterol. 2022 Mar;46(3):101836. doi: 10.1016/j.clinre.2021.101836. Epub 2021 Nov 18. Clin Res Hepatol Gastroenterol. 2022. PMID: 34800682