Barman J - Search Results

1

A large-scale chemical modification screen identifies design rules to generate siRNAs with high activity, high stability and low toxicity.

Bramsen JB, Laursen MB, Nielsen AF, Hansen TB, Bus C, Langkjaer N, Babu BR, Højland T, Abramov M, Van Aerschot A, Odadzic D, Smicius R, Haas J, Andree C, Barman J, Wenska M, Srivastava P, Zhou C, Honcharenko D, Hess S, Müller E, Bobkov GV, Mikhailov SN, Fava E, Meyer TF, Chattopadhyaya J, Zerial M, Engels JW, Herdewijn P, Wengel J, Kjems J. Bramsen JB, et al. Among authors: barman j. Nucleic Acids Res. 2009 May;37(9):2867-81. doi: 10.1093/nar/gkp106. Epub 2009 Mar 12. Nucleic Acids Res. 2009. PMID: 19282453 Free PMC article.

2

Oxetane modified, conformationally constrained, antisense oligodeoxyribonucleotides function efficiently as gene silencing molecules.

Opalinska JB, Kalota A, Gifford LK, Lu P, Jen KY, Pradeepkumar PI, Barman J, Kim TK, Swider CR, Chattopadhyaya J, Gewirtz AM. Opalinska JB, et al. Among authors: barman j. Nucleic Acids Res. 2004 Oct 28;32(19):5791-9. doi: 10.1093/nar/gkh893. Print 2004. Nucleic Acids Res. 2004. PMID: 15514112 Free PMC article.

3

Comparison of the RNase H cleavage kinetics and blood serum stability of the north-conformationally constrained and 2'-alkoxy modified oligonucleotides.

Honcharenko D, Barman J, Varghese OP, Chattopadhyaya J. Honcharenko D, et al. Among authors: barman j. Biochemistry. 2007 May 15;46(19):5635-46. doi: 10.1021/bi0620205. Epub 2007 Apr 6. Biochemistry. 2007. PMID: 17411072

4

Five- and six-membered conformationally locked 2',4'-carbocyclic ribo-thymidines: synthesis, structure, and biochemical studies.

Srivastava P, Barman J, Pathmasiri W, Plashkevych O, Wenska M, Chattopadhyaya J. Srivastava P, et al. Among authors: barman j. J Am Chem Soc. 2007 Jul 4;129(26):8362-79. doi: 10.1021/ja071106y. Epub 2007 Jun 7. J Am Chem Soc. 2007. PMID: 17552524

5

Conformationally constrained 2'-N,4'-C-ethylene-bridged thymidine (aza-ENA-T): synthesis, structure, physical, and biochemical studies of aza-ENA-T-modified oligonucleotides.

Varghese OP, Barman J, Pathmasiri W, Plashkevych O, Honcharenko D, Chattopadhyaya J. Varghese OP, et al. Among authors: barman j. J Am Chem Soc. 2006 Nov 29;128(47):15173-87. doi: 10.1021/ja0634977. J Am Chem Soc. 2006. PMID: 17117869

6

Synthesis and structure of novel conformationally constrained 1',2'-azetidine-fused bicyclic pyrimidine nucleosides: their incorporation into oligo-DNAs and thermal stability of the heteroduplexes.

Honcharenko D, Varghese OP, Plashkevych O, Barman J, Chattopadhyaya J. Honcharenko D, et al. Among authors: barman j. J Org Chem. 2006 Jan 6;71(1):299-314. doi: 10.1021/jo052115x. J Org Chem. 2006. PMID: 16388649

7

Non-identical electronic characters of the internucleotidic phosphates in RNA modulate the chemical reactivity of the phosphodiester bonds.

Barman J, Acharya S, Zhou C, Chatterjee S, Engström A, Chattopadhyaya J. Barman J, et al. Org Biomol Chem. 2006 Mar 7;4(5):928-41. doi: 10.1039/b516733g. Epub 2006 Feb 2. Org Biomol Chem. 2006. PMID: 16493477

8

Facile preparation of the oxetane-nucleosides.

Bogucka M, Naus P, Pathmasiri W, Barman J, Chattopadhyaya J. Bogucka M, et al. Among authors: barman j. Org Biomol Chem. 2005 Dec 21;3(24):4362-72. doi: 10.1039/b511406c. Epub 2005 Nov 7. Org Biomol Chem. 2005. PMID: 16327897

9

Significant pKa perturbation of nucleobases is an intrinsic property of the sequence context in DNA and RNA.

Acharya S, Barman J, Cheruku P, Chatterjee S, Acharya P, Isaksson J, Chattopadhyaya J. Acharya S, et al. Among authors: barman j. J Am Chem Soc. 2004 Jul 21;126(28):8674-81. doi: 10.1021/ja048484c. J Am Chem Soc. 2004. PMID: 15250719

10

Single-stranded adenine-rich DNA and RNA retain structural characteristics of their respective double-stranded conformations and show directional differences in stacking pattern.

Isaksson J, Acharya S, Barman J, Cheruku P, Chattopadhyaya J. Isaksson J, et al. Among authors: barman j. Biochemistry. 2004 Dec 28;43(51):15996-6010. doi: 10.1021/bi048221v. Biochemistry. 2004. PMID: 15609994

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