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Release of soluble CD40L from platelets is regulated by glycoprotein IIb/IIIa and actin polymerization.
Furman MI, Krueger LA, Linden MD, Barnard MR, Frelinger AL 3rd, Michelson AD. Furman MI, et al. Among authors: barnard mr. J Am Coll Cardiol. 2004 Jun 16;43(12):2319-25. doi: 10.1016/j.jacc.2003.12.055. J Am Coll Cardiol. 2004. PMID: 15193700
Effect of adenosine A2 receptor stimulation on platelet activation-aggregation: differences between canine and human models.
Linden MD, Barnard MR, Frelinger AL, Michelson AD, Przyklenk K. Linden MD, et al. Among authors: barnard mr. Thromb Res. 2008;121(5):689-98. doi: 10.1016/j.thromres.2007.07.002. Epub 2007 Aug 28. Thromb Res. 2008. PMID: 17727923 Free PMC article.
Antiplatelet activity, P2Y₁ and P2Y₁₂ inhibition, and metabolism in plasma of stereoisomers of diadenosine 5',5'″-P¹ ,P⁴-dithio-P²,P³-chloromethylenetetraphosphate.
Chang H, Yanachkov IB, Dix EJ, Yanachkova M, Li Y, Barnard MR, Wright GE, Michelson AD, Frelinger AL 3rd. Chang H, et al. Among authors: barnard mr. PLoS One. 2014 Apr 10;9(4):e94780. doi: 10.1371/journal.pone.0094780. eCollection 2014. PLoS One. 2014. PMID: 24722456 Free PMC article.
Clopidogrel pharmacokinetics and pharmacodynamics vary widely despite exclusion or control of polymorphisms (CYP2C19, ABCB1, PON1), noncompliance, diet, smoking, co-medications (including proton pump inhibitors), and pre-existent variability in platelet function.
Frelinger AL 3rd, Bhatt DL, Lee RD, Mulford DJ, Wu J, Nudurupati S, Nigam A, Lampa M, Brooks JK, Barnard MR, Michelson AD. Frelinger AL 3rd, et al. Among authors: barnard mr. J Am Coll Cardiol. 2013 Feb 26;61(8):872-9. doi: 10.1016/j.jacc.2012.11.040. Epub 2013 Jan 16. J Am Coll Cardiol. 2013. PMID: 23333143 Free article. Clinical Trial.
P2Y12 receptor blockade augments glycoprotein IIb-IIIa antagonist inhibition of platelet activation, aggregation, and procoagulant activity.
Berny-Lang MA, Jakubowski JA, Sugidachi A, Barnard MR, Michelson AD, Frelinger AL 3rd. Berny-Lang MA, et al. Among authors: barnard mr. J Am Heart Assoc. 2013 May 15;2(3):e000026. doi: 10.1161/JAHA.113.000026. J Am Heart Assoc. 2013. PMID: 23676293 Free PMC article.
Immunophenotypic analysis of platelets.
Krueger LA, Barnard MR, Frelinger AL 3rd, Furman MI, Michelson AD. Krueger LA, et al. Among authors: barnard mr. Curr Protoc Cytom. 2002 Feb;Chapter 6:Unit 6.10. doi: 10.1002/0471142956.cy0610s19. Curr Protoc Cytom. 2002. PMID: 18770767
Whole blood analysis of leukocyte-platelet aggregates.
Barnard MR, Krueger LA, Frelinger AL 3rd, Furman MI, Michelson AD. Barnard MR, et al. Curr Protoc Cytom. 2003 May;Chapter 6:Unit 6.15. doi: 10.1002/0471142956.cy0615s24. Curr Protoc Cytom. 2003. PMID: 18770779
The platelet hyporeactivity of extremely low birth weight neonates is age-dependent.
Bednarek FJ, Bean S, Barnard MR, Frelinger AL, Michelson AD. Bednarek FJ, et al. Among authors: barnard mr. Thromb Res. 2009 May;124(1):42-5. doi: 10.1016/j.thromres.2008.10.004. Epub 2008 Nov 20. Thromb Res. 2009. PMID: 19026437
The active metabolite of prasugrel inhibits ADP-stimulated thrombo-inflammatory markers of platelet activation: Influence of other blood cells, calcium, and aspirin.
Frelinger AL 3rd, Jakubowski JA, Li Y, Barnard MR, Fox ML, Linden MD, Sugidachi A, Winters KJ, Furman MI, Michelson AD. Frelinger AL 3rd, et al. Among authors: barnard mr. Thromb Haemost. 2007 Jul;98(1):192-200. Thromb Haemost. 2007. PMID: 17598013
Residual arachidonic acid-induced platelet activation via an adenosine diphosphate-dependent but cyclooxygenase-1- and cyclooxygenase-2-independent pathway: a 700-patient study of aspirin resistance.
Frelinger AL 3rd, Furman MI, Linden MD, Li Y, Fox ML, Barnard MR, Michelson AD. Frelinger AL 3rd, et al. Among authors: barnard mr. Circulation. 2006 Jun 27;113(25):2888-96. doi: 10.1161/CIRCULATIONAHA.105.596627. Epub 2006 Jun 19. Circulation. 2006. PMID: 16785341
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