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Molecular identification of high and low affinity receptors for nicotinic acid.
Wise A, Foord SM, Fraser NJ, Barnes AA, Elshourbagy N, Eilert M, Ignar DM, Murdock PR, Steplewski K, Green A, Brown AJ, Dowell SJ, Szekeres PG, Hassall DG, Marshall FH, Wilson S, Pike NB. Wise A, et al. Among authors: barnes aa. J Biol Chem. 2003 Mar 14;278(11):9869-74. doi: 10.1074/jbc.M210695200. Epub 2003 Jan 9. J Biol Chem. 2003. PMID: 12522134 Free article.
The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids.
Brown AJ, Goldsworthy SM, Barnes AA, Eilert MM, Tcheang L, Daniels D, Muir AI, Wigglesworth MJ, Kinghorn I, Fraser NJ, Pike NB, Strum JC, Steplewski KM, Murdock PR, Holder JC, Marshall FH, Szekeres PG, Wilson S, Ignar DM, Foord SM, Wise A, Dowell SJ. Brown AJ, et al. Among authors: barnes aa. J Biol Chem. 2003 Mar 28;278(13):11312-9. doi: 10.1074/jbc.M211609200. Epub 2002 Dec 19. J Biol Chem. 2003. PMID: 12496283 Free article.
Complex chimeras to map ligand binding sites of GPCRs.
Gearing KL, Barnes A, Barnett J, Brown A, Cousens D, Dowell S, Green A, Patel K, Thomas P, Volpe F, Marshall F. Gearing KL, et al. Protein Eng. 2003 May;16(5):365-72. doi: 10.1093/protein/gzg045. Protein Eng. 2003. PMID: 12826728
A coding polymorphism in the CYSLT2 receptor with reduced affinity to LTD4 is associated with asthma.
Pillai SG, Cousens DJ, Barnes AA, Buckley PT, Chiano MN, Hosking LK, Cameron LA, Fling ME, Foley JJ, Green A, Sarau HM, Schmidt DB, Sprankle CS, Blumenthal MN, Vestbo J, Kennedy-Wilson K, Wixted WE, Wagner MJ, Anderson WH, Ignar DM; Investigators of the GAIN Network. Pillai SG, et al. Among authors: barnes aa. Pharmacogenetics. 2004 Sep;14(9):627-33. doi: 10.1097/00008571-200409000-00007. Pharmacogenetics. 2004. PMID: 15475736
GSK962040: a small molecule, selective motilin receptor agonist, effective as a stimulant of human and rabbit gastrointestinal motility.
Sanger GJ, Westaway SM, Barnes AA, Macpherson DT, Muir AI, Jarvie EM, Bolton VN, Cellek S, Näslund E, Hellström PM, Borman RA, Unsworth WP, Matthews KL, Lee K. Sanger GJ, et al. Among authors: barnes aa. Neurogastroenterol Motil. 2009 Jun;21(6):657-64, e30-1. doi: 10.1111/j.1365-2982.2008.01270.x. Neurogastroenterol Motil. 2009. PMID: 19374732
15 results