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A neutralizing monoclonal antibody targeting the acid-sensitive region in chikungunya virus E2 protects from disease.
Selvarajah S, Sexton NR, Kahle KM, Fong RH, Mattia KA, Gardner J, Lu K, Liss NM, Salvador B, Tucker DF, Barnes T, Mabila M, Zhou X, Rossini G, Rucker JB, Sanders DA, Suhrbier A, Sambri V, Michault A, Muench MO, Doranz BJ, Simmons G. Selvarajah S, et al. Among authors: barnes t. PLoS Negl Trop Dis. 2013 Sep 12;7(9):e2423. doi: 10.1371/journal.pntd.0002423. eCollection 2013. PLoS Negl Trop Dis. 2013. PMID: 24069479 Free PMC article.
HCV E2 core structures and mAbs: something is still missing.
Castelli M, Clementi N, Sautto GA, Pfaff J, Kahle KM, Barnes T, Doranz BJ, Dal Peraro M, Clementi M, Burioni R, Mancini N. Castelli M, et al. Among authors: barnes t. Drug Discov Today. 2014 Dec;19(12):1964-70. doi: 10.1016/j.drudis.2014.08.011. Epub 2014 Aug 27. Drug Discov Today. 2014. PMID: 25172800 Free PMC article. Review.
Exposure of epitope residues on the outer face of the chikungunya virus envelope trimer determines antibody neutralizing efficacy.
Fong RH, Banik SS, Mattia K, Barnes T, Tucker D, Liss N, Lu K, Selvarajah S, Srinivasan S, Mabila M, Miller A, Muench MO, Michault A, Rucker JB, Paes C, Simmons G, Kahle KM, Doranz BJ. Fong RH, et al. Among authors: barnes t. J Virol. 2014 Dec;88(24):14364-79. doi: 10.1128/JVI.01943-14. Epub 2014 Oct 1. J Virol. 2014. PMID: 25275138 Free PMC article.
Neutralizing human antibodies prevent Zika virus replication and fetal disease in mice.
Sapparapu G, Fernandez E, Kose N, Bin Cao, Fox JM, Bombardi RG, Zhao H, Nelson CA, Bryan AL, Barnes T, Davidson E, Mysorekar IU, Fremont DH, Doranz BJ, Diamond MS, Crowe JE. Sapparapu G, et al. Among authors: barnes t. Nature. 2016 Dec 15;540(7633):443-447. doi: 10.1038/nature20564. Epub 2016 Nov 7. Nature. 2016. PMID: 27819683 Free PMC article.
Isolation of state-dependent monoclonal antibodies against the 12-transmembrane domain glucose transporter 4 using virus-like particles.
Tucker DF, Sullivan JT, Mattia KA, Fisher CR, Barnes T, Mabila MN, Wilf R, Sulli C, Pitts M, Payne RJ, Hall M, Huston-Paterson D, Deng X, Davidson E, Willis SH, Doranz BJ, Chambers R, Rucker JB. Tucker DF, et al. Among authors: barnes t. Proc Natl Acad Sci U S A. 2018 May 29;115(22):E4990-E4999. doi: 10.1073/pnas.1716788115. Epub 2018 May 16. Proc Natl Acad Sci U S A. 2018. PMID: 29769329 Free PMC article.
Increased breadth of HIV-1 neutralization achieved by diverse antibody clones each with limited neutralization breadth.
Chukwuma VU, Kose N, Sather DN, Sapparapu G, Falk R, King H, Singh V, Lampley R, Malherbe DC, Ditto NT, Sullivan JT, Barnes T, Doranz BJ, Labranche CC, Montefiori DC, Kalams SA, Haigwood NL, Crowe JE Jr. Chukwuma VU, et al. Among authors: barnes t. PLoS One. 2018 Dec 19;13(12):e0209437. doi: 10.1371/journal.pone.0209437. eCollection 2018. PLoS One. 2018. PMID: 30566528 Free PMC article.
1,091 results