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The CRISPR/Cas bacterial immune system cleaves bacteriophage and plasmid DNA.
Garneau JE, Dupuis MÈ, Villion M, Romero DA, Barrangou R, Boyaval P, Fremaux C, Horvath P, Magadán AH, Moineau S. Garneau JE, et al. Nature. 2010 Nov 4;468(7320):67-71. doi: 10.1038/nature09523. Nature. 2010. PMID: 21048762
CRISPR provides acquired resistance against viruses in prokaryotes.
Barrangou R, Fremaux C, Deveau H, Richards M, Boyaval P, Moineau S, Romero DA, Horvath P. Barrangou R, et al. Science. 2007 Mar 23;315(5819):1709-12. doi: 10.1126/science.1138140. Science. 2007. PMID: 17379808
Diversity, activity, and evolution of CRISPR loci in Streptococcus thermophilus.
Horvath P, Romero DA, Coûté-Monvoisin AC, Richards M, Deveau H, Moineau S, Boyaval P, Fremaux C, Barrangou R. Horvath P, et al. J Bacteriol. 2008 Feb;190(4):1401-12. doi: 10.1128/JB.01415-07. Epub 2007 Dec 7. J Bacteriol. 2008. PMID: 18065539 Free PMC article.
Phage response to CRISPR-encoded resistance in Streptococcus thermophilus.
Deveau H, Barrangou R, Garneau JE, Labonté J, Fremaux C, Boyaval P, Romero DA, Horvath P, Moineau S. Deveau H, et al. J Bacteriol. 2008 Feb;190(4):1390-400. doi: 10.1128/JB.01412-07. Epub 2007 Dec 7. J Bacteriol. 2008. PMID: 18065545 Free PMC article.
CRISPR/Cas, the immune system of bacteria and archaea.
Horvath P, Barrangou R. Horvath P, et al. Science. 2010 Jan 8;327(5962):167-70. doi: 10.1126/science.1179555. Science. 2010. PMID: 20056882 Review.
Evolution and classification of the CRISPR-Cas systems.
Makarova KS, Haft DH, Barrangou R, Brouns SJ, Charpentier E, Horvath P, Moineau S, Mojica FJ, Wolf YI, Yakunin AF, van der Oost J, Koonin EV. Makarova KS, et al. Nat Rev Microbiol. 2011 Jun;9(6):467-77. doi: 10.1038/nrmicro2577. Epub 2011 May 9. Nat Rev Microbiol. 2011. PMID: 21552286 Free PMC article. Review.
The Streptococcus thermophilus CRISPR/Cas system provides immunity in Escherichia coli.
Sapranauskas R, Gasiunas G, Fremaux C, Barrangou R, Horvath P, Siksnys V. Sapranauskas R, et al. Nucleic Acids Res. 2011 Nov;39(21):9275-82. doi: 10.1093/nar/gkr606. Epub 2011 Aug 3. Nucleic Acids Res. 2011. PMID: 21813460 Free PMC article.
Phage-induced expression of CRISPR-associated proteins is revealed by shotgun proteomics in Streptococcus thermophilus.
Young JC, Dill BD, Pan C, Hettich RL, Banfield JF, Shah M, Fremaux C, Horvath P, Barrangou R, Verberkmoes NC. Young JC, et al. PLoS One. 2012;7(5):e38077. doi: 10.1371/journal.pone.0038077. Epub 2012 May 30. PLoS One. 2012. PMID: 22666452 Free PMC article.
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