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Recombinant, chimaeric live, attenuated vaccine (ChimeriVax) incorporating the envelope genes of Japanese encephalitis (SA14-14-2) virus and the capsid and nonstructural genes of yellow fever (17D) virus is safe, immunogenic and protective in non-human primates.
Monath TP, Soike K, Levenbook I, Zhang ZX, Arroyo J, Delagrave S, Myers G, Barrett AD, Shope RE, Ratterree M, Chambers TJ, Guirakhoo F. Monath TP, et al. Vaccine. 1999 Apr 9;17(15-16):1869-82. doi: 10.1016/s0264-410x(98)00487-3. Vaccine. 1999. PMID: 10217584
Nucleotide sequence of the envelope protein of a Turkish isolate of tick-borne encephalitis (TBE) virus is distinct from other viruses of the TBE virus complex.
Whitby JE, Whitby SN, Jennings AD, Stephenson JR, Barrett AD. Whitby JE, et al. J Gen Virol. 1993 May;74 ( Pt 5):921-4. doi: 10.1099/0022-1317-74-5-921. J Gen Virol. 1993. PMID: 8492100
Comparison of the nucleotide and deduced amino acid sequences of the envelope protein genes of the wild-type French viscerotropic strain of yellow fever virus and the live vaccine strain, French neurotropic vaccine, derived from it.
Jennings AD, Whitby JE, Minor PD, Barrett AD. Jennings AD, et al. Virology. 1993 Feb;192(2):692-5. doi: 10.1006/viro.1993.1090. Virology. 1993. PMID: 8421909
Attenuation of wild-type yellow fever virus by passage in HeLa cells.
Barrett AD, Monath TP, Cropp CB, Adkins JA, Ledger TN, Gould EA, Schlesinger JJ, Kinney RM, Trent DW. Barrett AD, et al. J Gen Virol. 1990 Oct;71 ( Pt 10):2301-6. doi: 10.1099/0022-1317-71-10-2301. J Gen Virol. 1990. PMID: 2230735
Attenuation of virulence of flaviviruses following passage in HeLa cells.
Dunster LM, Gibson CA, Stephenson JR, Minor PD, Barrett AD. Dunster LM, et al. J Gen Virol. 1990 Mar;71 ( Pt 3):601-7. doi: 10.1099/0022-1317-71-3-601. J Gen Virol. 1990. PMID: 2155996
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