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Increased susceptibility to hyperoxic lung injury and alveolar simplification in newborn rats by prenatal administration of benzo[a]pyrene.
Thakur VS, Liang YW, Lingappan K, Jiang W, Wang L, Barrios R, Zhou G, Guntupalli B, Shivanna B, Maturu P, Welty SE, Moorthy B, Couroucli XI. Thakur VS, et al. Among authors: barrios r. Toxicol Lett. 2014 Oct 15;230(2):322-32. doi: 10.1016/j.toxlet.2014.03.006. Epub 2014 Mar 19. Toxicol Lett. 2014. PMID: 24657529 Free PMC article.
Augmented oxygen-mediated transcriptional activation of cytochrome P450 (CYP)1A expression and increased susceptibilities to hyperoxic lung injury in transgenic mice carrying the human CYP1A1 or mouse 1A2 promoter in vivo.
Jiang W, Couroucli XI, Wang L, Barrios R, Moorthy B. Jiang W, et al. Among authors: barrios r. Biochem Biophys Res Commun. 2011 Apr 1;407(1):79-85. doi: 10.1016/j.bbrc.2011.02.113. Epub 2011 Mar 6. Biochem Biophys Res Commun. 2011. PMID: 21362406 Free PMC article.
Prenatal administration of the cytochrome P4501A inducer, Β-naphthoflavone (BNF), attenuates hyperoxic lung injury in newborn mice: implications for bronchopulmonary dysplasia (BPD) in premature infants.
Couroucli XI, Liang YH, Jiang W, Wang L, Barrios R, Yang P, Moorthy B. Couroucli XI, et al. Among authors: barrios r. Toxicol Appl Pharmacol. 2011 Oct 15;256(2):83-94. doi: 10.1016/j.taap.2011.06.018. Epub 2011 Jun 26. Toxicol Appl Pharmacol. 2011. PMID: 21745492 Free PMC article.
Mice deficient in the gene for cytochrome P450 (CYP)1A1 are more susceptible than wild-type to hyperoxic lung injury: evidence for protective role of CYP1A1 against oxidative stress.
Lingappan K, Jiang W, Wang L, Wang G, Couroucli XI, Shivanna B, Welty SE, Barrios R, Khan MF, Nebert DW, Roberts LJ, Moorthy B. Lingappan K, et al. Among authors: barrios r. Toxicol Sci. 2014 Sep;141(1):68-77. doi: 10.1093/toxsci/kfu106. Epub 2014 Jun 3. Toxicol Sci. 2014. PMID: 24893714 Free PMC article.
Newborn Mice Lacking the Gene for Cyp1a1 Are More Susceptible to Oxygen-Mediated Lung Injury, and Are Rescued by Postnatal β-Naphthoflavone Administration: Implications for Bronchopulmonary Dysplasia in Premature Infants.
Maturu P, Wei-Liang Y, Jiang W, Wang L, Lingappan K, Barrios R, Liang Y, Moorthy B, Couroucli XI. Maturu P, et al. Among authors: barrios r. Toxicol Sci. 2017 May 1;157(1):260-271. doi: 10.1093/toxsci/kfx036. Toxicol Sci. 2017. PMID: 28201809 Free PMC article.
Disruption of the Ah receptor gene alters the susceptibility of mice to oxygen-mediated regulation of pulmonary and hepatic cytochromes P4501A expression and exacerbates hyperoxic lung injury.
Jiang W, Welty SE, Couroucli XI, Barrios R, Kondraganti SR, Muthiah K, Yu L, Avery SE, Moorthy B. Jiang W, et al. Among authors: barrios r. J Pharmacol Exp Ther. 2004 Aug;310(2):512-9. doi: 10.1124/jpet.103.059766. Epub 2004 May 3. J Pharmacol Exp Ther. 2004. PMID: 15123765
374 results