Barton P - Search Results

1

A kinetic method for the determination of plasma protein binding of compounds unstable in plasma: Specific application to enalapril.

Wenlock MC, Barton P, Austin RP. Wenlock MC, et al. Among authors: barton p. J Pharm Biomed Anal. 2011 Jun 1;55(3):385-90. doi: 10.1016/j.jpba.2011.02.006. Epub 2011 Mar 2. J Pharm Biomed Anal. 2011. PMID: 21371844

2

Bioanalysis of Pseudomonas aeruginosa alkyl quinolone signalling molecules in infected mouse tissue using LC-MS/MS; and its application to a pharmacodynamic evaluation of MvfR inhibition.

Turnpenny P, Padfield A, Barton P, Teague J, Rahme LG, Pucci MJ, Zahler R, Rubio A. Turnpenny P, et al. Among authors: barton p. J Pharm Biomed Anal. 2017 May 30;139:44-53. doi: 10.1016/j.jpba.2017.02.034. Epub 2017 Feb 28. J Pharm Biomed Anal. 2017. PMID: 28273650

3

The thermodynamics of the partitioning of ionizing molecules between aqueous buffers and phospholipid membranes.

Austin RP, Barton P, Davis AM, Fessey RE, Wenlock MC. Austin RP, et al. Among authors: barton p. Pharm Res. 2005 Oct;22(10):1649-57. doi: 10.1007/s11095-005-6336-7. Epub 2005 Sep 22. Pharm Res. 2005. PMID: 16180122

4

The binding of drugs to hepatocytes and its relationship to physicochemical properties.

Austin RP, Barton P, Mohmed S, Riley RJ. Austin RP, et al. Among authors: barton p. Drug Metab Dispos. 2005 Mar;33(3):419-25. doi: 10.1124/dmd.104.002436. Epub 2004 Dec 22. Drug Metab Dispos. 2005. PMID: 15616151

5

The influence of nonspecific microsomal binding on apparent intrinsic clearance, and its prediction from physicochemical properties.

Austin RP, Barton P, Cockroft SL, Wenlock MC, Riley RJ. Austin RP, et al. Among authors: barton p. Drug Metab Dispos. 2002 Dec;30(12):1497-503. doi: 10.1124/dmd.30.12.1497. Drug Metab Dispos. 2002. PMID: 12433825

6

A highly automated assay for determining the aqueous equilibrium solubility of drug discovery compounds.

Wenlock MC, Austin RP, Potter T, Barton P. Wenlock MC, et al. Among authors: barton p. J Lab Autom. 2011 Aug;16(4):276-84. doi: 10.1016/j.jala.2010.10.002. Epub 2011 Mar 26. J Lab Autom. 2011. PMID: 21764023

7

A rapid computational filter for predicting the rate of human renal clearance.

Paine SW, Barton P, Bird J, Denton R, Menochet K, Smith A, Tomkinson NP, Chohan KK. Paine SW, et al. Among authors: barton p. J Mol Graph Model. 2010 Dec;29(4):529-37. doi: 10.1016/j.jmgm.2010.10.003. Epub 2010 Oct 20. J Mol Graph Model. 2010. PMID: 21075652

8

A method for measuring the lipophilicity of compounds in mixtures of 10.

Wenlock MC, Potter T, Barton P, Austin RP. Wenlock MC, et al. Among authors: barton p. J Biomol Screen. 2011 Mar;16(3):348-55. doi: 10.1177/1087057110396372. Epub 2011 Feb 22. J Biomol Screen. 2011. PMID: 21343602

9

Lipophilicity of acidic compounds: impact of ion pair partitioning on drug design.

Wenlock MC, Barton P, Luker T. Wenlock MC, et al. Among authors: barton p. Bioorg Med Chem Lett. 2011 Jun 15;21(12):3550-6. doi: 10.1016/j.bmcl.2011.04.133. Epub 2011 May 5. Bioorg Med Chem Lett. 2011. PMID: 21601448

10

The effect of ionic strength on liposome-buffer and 1-octanol-buffer distribution coefficients.

Austin RP, Barton P, Davis AM, Manners CN, Stansfield MC. Austin RP, et al. Among authors: barton p. J Pharm Sci. 1998 May;87(5):599-607. doi: 10.1021/js9703481. J Pharm Sci. 1998. PMID: 9572911

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