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Breaking peripheral immune tolerance to CNS antigens in neurodegenerative diseases: boosting autoimmunity to fight-off chronic neuroinflammation.
Schwartz M, Baruch K. Schwartz M, et al. Among authors: baruch k. J Autoimmun. 2014 Nov;54:8-14. doi: 10.1016/j.jaut.2014.08.002. Epub 2014 Sep 8. J Autoimmun. 2014. PMID: 25199710 Review.
A Unique Microglia Type Associated with Restricting Development of Alzheimer's Disease.
Keren-Shaul H, Spinrad A, Weiner A, Matcovitch-Natan O, Dvir-Szternfeld R, Ulland TK, David E, Baruch K, Lara-Astaiso D, Toth B, Itzkovitz S, Colonna M, Schwartz M, Amit I. Keren-Shaul H, et al. Among authors: baruch k. Cell. 2017 Jun 15;169(7):1276-1290.e17. doi: 10.1016/j.cell.2017.05.018. Epub 2017 Jun 8. Cell. 2017. PMID: 28602351
Circulating Monocytes in between the Gut and the Mind.
Baruch K, Schwartz M. Baruch K, et al. Cell Stem Cell. 2016 Jun 2;18(6):689-691. doi: 10.1016/j.stem.2016.05.008. Cell Stem Cell. 2016. PMID: 27257756
Microglia development follows a stepwise program to regulate brain homeostasis.
Matcovitch-Natan O, Winter DR, Giladi A, Vargas Aguilar S, Spinrad A, Sarrazin S, Ben-Yehuda H, David E, Zelada González F, Perrin P, Keren-Shaul H, Gury M, Lara-Astaiso D, Thaiss CA, Cohen M, Bahar Halpern K, Baruch K, Deczkowska A, Lorenzo-Vivas E, Itzkovitz S, Elinav E, Sieweke MH, Schwartz M, Amit I. Matcovitch-Natan O, et al. Among authors: baruch k. Science. 2016 Aug 19;353(6301):aad8670. doi: 10.1126/science.aad8670. Epub 2016 Jun 23. Science. 2016. PMID: 27338705
PD-1/PD-L1 checkpoint blockade harnesses monocyte-derived macrophages to combat cognitive impairment in a tauopathy mouse model.
Rosenzweig N, Dvir-Szternfeld R, Tsitsou-Kampeli A, Keren-Shaul H, Ben-Yehuda H, Weill-Raynal P, Cahalon L, Kertser A, Baruch K, Amit I, Weiner A, Schwartz M. Rosenzweig N, et al. Among authors: baruch k. Nat Commun. 2019 Jan 28;10(1):465. doi: 10.1038/s41467-019-08352-5. Nat Commun. 2019. PMID: 30692527 Free PMC article.
Type I/II Interferon Balance in the Regulation of Brain Physiology and Pathology.
Deczkowska A, Baruch K, Schwartz M. Deczkowska A, et al. Among authors: baruch k. Trends Immunol. 2016 Mar;37(3):181-192. doi: 10.1016/ Epub 2016 Feb 11. Trends Immunol. 2016. PMID: 26877243 Review.
PD-1 immune checkpoint blockade reduces pathology and improves memory in mouse models of Alzheimer's disease.
Baruch K, Deczkowska A, Rosenzweig N, Tsitsou-Kampeli A, Sharif AM, Matcovitch-Natan O, Kertser A, David E, Amit I, Schwartz M. Baruch K, et al. Nat Med. 2016 Feb;22(2):135-7. doi: 10.1038/nm.4022. Epub 2016 Jan 18. Nat Med. 2016. PMID: 26779813
Breaking immune tolerance by targeting Foxp3(+) regulatory T cells mitigates Alzheimer's disease pathology.
Baruch K, Rosenzweig N, Kertser A, Deczkowska A, Sharif AM, Spinrad A, Tsitsou-Kampeli A, Sarel A, Cahalon L, Schwartz M. Baruch K, et al. Nat Commun. 2015 Aug 18;6:7967. doi: 10.1038/ncomms8967. Nat Commun. 2015. PMID: 26284939 Free PMC article.
Cerebral nitric oxide represses choroid plexus NFκB-dependent gateway activity for leukocyte trafficking.
Baruch K, Kertser A, Porat Z, Schwartz M. Baruch K, et al. EMBO J. 2015 Jul 2;34(13):1816-28. doi: 10.15252/embj.201591468. Epub 2015 May 4. EMBO J. 2015. PMID: 25940071 Free PMC article.
TNF-like weak inducer of apoptosis promotes blood brain barrier disruption and increases neuronal cell death in MRL/lpr mice.
Wen J, Doerner J, Weidenheim K, Xia Y, Stock A, Michaelson JS, Baruch K, Deczkowska A, Gulinello M, Schwartz M, Burkly LC, Putterman C. Wen J, et al. Among authors: baruch k. J Autoimmun. 2015 Jun;60:40-50. doi: 10.1016/j.jaut.2015.03.005. Epub 2015 Apr 22. J Autoimmun. 2015. PMID: 25911200 Free PMC article.
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