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DNA damage responses to oxidative stress.
Barzilai A, Yamamoto K. Barzilai A, et al. DNA Repair (Amst). 2004 Aug-Sep;3(8-9):1109-15. doi: 10.1016/j.dnarep.2004.03.002. DNA Repair (Amst). 2004. PMID: 15279799 Review.
Genome maintenance in the nervous system; insight into the role of the DNA damage response in brain development and disease.
Barzilai A, McKinnon PJ. Barzilai A, et al. DNA Repair (Amst). 2013 Aug;12(8):541-2. doi: 10.1016/j.dnarep.2013.06.005. DNA Repair (Amst). 2013. PMID: 23870284 No abstract available.
Inactive Atm abrogates DSB repair in mouse cerebellum more than does Atm loss, without causing a neurological phenotype.
Tal E, Alfo M, Zha S, Barzilai A, De Zeeuw CI, Ziv Y, Shiloh Y. Tal E, et al. Among authors: barzilai a. DNA Repair (Amst). 2018 Dec;72:10-17. doi: 10.1016/j.dnarep.2018.10.001. Epub 2018 Oct 11. DNA Repair (Amst). 2018. PMID: 30348496
Investigation of the functional link between ATM and NBS1 in the DNA damage response in the mouse cerebellum.
Dar I, Yosha G, Elfassy R, Galron R, Wang ZQ, Shiloh Y, Barzilai A. Dar I, et al. Among authors: barzilai a. J Biol Chem. 2011 Apr 29;286(17):15361-76. doi: 10.1074/jbc.M110.204172. Epub 2011 Feb 7. J Biol Chem. 2011. PMID: 21300797 Free PMC article.
Conditional inactivation of the NBS1 gene in the mouse central nervous system leads to neurodegeneration and disorganization of the visual system.
Baranes K, Raz-Prag D, Nitzan A, Galron R, Ashery-Padan R, Rotenstreich Y, Assaf Y, Shiloh Y, Wang ZQ, Barzilai A, Solomon AS. Baranes K, et al. Among authors: barzilai a. Exp Neurol. 2009 Jul;218(1):24-32. doi: 10.1016/j.expneurol.2009.03.026. Epub 2009 Apr 1. Exp Neurol. 2009. PMID: 19345213
Nuclear ataxia-telangiectasia mutated (ATM) mediates the cellular response to DNA double strand breaks in human neuron-like cells.
Biton S, Dar I, Mittelman L, Pereg Y, Barzilai A, Shiloh Y. Biton S, et al. Among authors: barzilai a. J Biol Chem. 2006 Jun 23;281(25):17482-91. doi: 10.1074/jbc.M601895200. Epub 2006 Apr 20. J Biol Chem. 2006. PMID: 16627474
Accumulation of DNA damage and reduced levels of nicotine adenine dinucleotide in the brains of Atm-deficient mice.
Stern N, Hochman A, Zemach N, Weizman N, Hammel I, Shiloh Y, Rotman G, Barzilai A. Stern N, et al. Among authors: barzilai a. J Biol Chem. 2002 Jan 4;277(1):602-8. doi: 10.1074/jbc.M106798200. Epub 2001 Oct 25. J Biol Chem. 2002. PMID: 11679583
Analysis of the ataxia telangiectasia mutated-mediated DNA damage response in murine cerebellar neurons.
Dar I, Biton S, Shiloh Y, Barzilai A. Dar I, et al. Among authors: barzilai a. J Neurosci. 2006 Jul 19;26(29):7767-74. doi: 10.1523/JNEUROSCI.2055-06.2006. J Neurosci. 2006. PMID: 16855104 Free PMC article.
Impaired genomic stability and increased oxidative stress exacerbate different features of Ataxia-telangiectasia.
Ziv S, Brenner O, Amariglio N, Smorodinsky NI, Galron R, Carrion DV, Zhang W, Sharma GG, Pandita RK, Agarwal M, Elkon R, Katzin N, Bar-Am I, Pandita TK, Kucherlapati R, Rechavi G, Shiloh Y, Barzilai A. Ziv S, et al. Among authors: barzilai a. Hum Mol Genet. 2005 Oct 1;14(19):2929-43. doi: 10.1093/hmg/ddi324. Epub 2005 Sep 8. Hum Mol Genet. 2005. PMID: 16150740
The interrelations between malfunctioning DNA damage response (DDR) and the functionality of the neuro-glio-vascular unit.
Barzilai A. Barzilai A. DNA Repair (Amst). 2013 Aug;12(8):543-57. doi: 10.1016/j.dnarep.2013.04.007. Epub 2013 May 23. DNA Repair (Amst). 2013. PMID: 23706773 Review.
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