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Sybil: A Validated Deep Learning Model to Predict Future Lung Cancer Risk From a Single Low-Dose Chest Computed Tomography.
Mikhael PG, Wohlwend J, Yala A, Karstens L, Xiang J, Takigami AK, Bourgouin PP, Chan P, Mrah S, Amayri W, Juan YH, Yang CT, Wan YL, Lin G, Sequist LV, Fintelmann FJ, Barzilay R. Mikhael PG, et al. Among authors: barzilay r. J Clin Oncol. 2023 Apr 20;41(12):2191-2200. doi: 10.1200/JCO.22.01345. Epub 2023 Jan 12. J Clin Oncol. 2023. PMID: 36634294 Free PMC article.
Artificial Intelligence and Machine Learning in Lung Cancer Screening.
Adams SJ, Mikhael P, Wohlwend J, Barzilay R, Sequist LV, Fintelmann FJ. Adams SJ, et al. Among authors: barzilay r. Thorac Surg Clin. 2023 Nov;33(4):401-409. doi: 10.1016/j.thorsurg.2023.03.001. Epub 2023 May 12. Thorac Surg Clin. 2023. PMID: 37806742 Review.
De novo design of protein structure and function with RFdiffusion.
Watson JL, Juergens D, Bennett NR, Trippe BL, Yim J, Eisenach HE, Ahern W, Borst AJ, Ragotte RJ, Milles LF, Wicky BIM, Hanikel N, Pellock SJ, Courbet A, Sheffler W, Wang J, Venkatesh P, Sappington I, Torres SV, Lauko A, De Bortoli V, Mathieu E, Ovchinnikov S, Barzilay R, Jaakkola TS, DiMaio F, Baek M, Baker D. Watson JL, et al. Among authors: barzilay r. Nature. 2023 Aug;620(7976):1089-1100. doi: 10.1038/s41586-023-06415-8. Epub 2023 Jul 11. Nature. 2023. PMID: 37433327 Free PMC article.
AI-driven discovery of synergistic drug combinations against pancreatic cancer.
Pourmousa M, Jain S, Barnaeva E, Jin W, Hochuli J, Itkin Z, Maxfield T, Melo-Filho C, Thieme A, Wilson K, Klumpp-Thomas C, Michael S, Southall N, Jaakkola T, Muratov EN, Barzilay R, Tropsha A, Ferrer M, Zakharov AV. Pourmousa M, et al. Among authors: barzilay r. Nat Commun. 2025 Apr 29;16(1):4020. doi: 10.1038/s41467-025-56818-6. Nat Commun. 2025. PMID: 40301300 Free PMC article.
Atom-level enzyme active site scaffolding using RFdiffusion2.
Ahern W, Yim J, Tischer D, Salike S, Woodbury SM, Kim D, Kalvet I, Kipnis Y, Coventry B, Altae-Tran HR, Bauer MS, Barzilay R, Jaakkola TS, Krishna R, Baker D. Ahern W, et al. Among authors: barzilay r. Nat Methods. 2026 Jan;23(1):96-105. doi: 10.1038/s41592-025-02975-x. Epub 2025 Dec 3. Nat Methods. 2026. PMID: 41339749 Free PMC article.
Distinct chemical environments in biomolecular condensates.
Kilgore HR, Mikhael PG, Overholt KJ, Boija A, Hannett NM, Van Dongen C, Lee TI, Chang YT, Barzilay R, Young RA. Kilgore HR, et al. Among authors: barzilay r. Nat Chem Biol. 2024 Mar;20(3):291-301. doi: 10.1038/s41589-023-01432-0. Epub 2023 Sep 28. Nat Chem Biol. 2024. PMID: 37770698 Free PMC article.
223 results