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Platelet-activating factor receptor and ADAM10 mediate responses to Staphylococcus aureus in epithelial cells.
Lemjabbar H, Basbaum C. Lemjabbar H, et al. Among authors: basbaum c. Nat Med. 2002 Jan;8(1):41-6. doi: 10.1038/nm0102-41. Nat Med. 2002. PMID: 11786905
Adenosine up-regulation of the mucin gene, MUC2, in asthma.
McNamara N, Gallup M, Khong A, Sucher A, Maltseva I, Fahy J, Basbaum C. McNamara N, et al. Among authors: basbaum c. FASEB J. 2004 Nov;18(14):1770-2. doi: 10.1096/fj.04-1964fje. Epub 2004 Sep 2. FASEB J. 2004. PMID: 15345696
ATP transduces signals from ASGM1, a glycolipid that functions as a bacterial receptor.
McNamara N, Khong A, McKemy D, Caterina M, Boyer J, Julius D, Basbaum C. McNamara N, et al. Among authors: basbaum c. Proc Natl Acad Sci U S A. 2001 Jul 31;98(16):9086-91. doi: 10.1073/pnas.161290898. Proc Natl Acad Sci U S A. 2001. PMID: 11481474 Free PMC article.
This response links ASGM1 to cytoplasmic signaling molecules and results in activation of phospholipase C, Ca(2+) mobilization, phosphorylation of a mitogen-activated protein kinase (Erk 1/2), and activation of mucin transcription. ...
This response links ASGM1 to cytoplasmic signaling molecules and results in activation of phospholipase C, Ca(2+) mobilization, phosp …
Distribution of lysozyme and mucin (MUC2 and MUC3) mRNA in human bronchus.
Dohrman A, Tsuda T, Escudier E, Cardone M, Jany B, Gum J, Kim Y, Basbaum C. Dohrman A, et al. Among authors: basbaum c. Exp Lung Res. 1994 Jul-Aug;20(4):367-80. doi: 10.3109/01902149409064393. Exp Lung Res. 1994. PMID: 7988497
Allergen-induced IL-9 directly stimulates mucin transcription in respiratory epithelial cells.
Longphre M, Li D, Gallup M, Drori E, Ordoñez CL, Redman T, Wenzel S, Bice DE, Fahy JV, Basbaum C. Longphre M, et al. Among authors: basbaum c. J Clin Invest. 1999 Nov;104(10):1375-82. doi: 10.1172/JCI6097. J Clin Invest. 1999. PMID: 10562299 Free PMC article.
Control of mucin transcription by diverse injury-induced signaling pathways.
Basbaum C, Lemjabbar H, Longphre M, Li D, Gensch E, McNamara N. Basbaum C, et al. Am J Respir Crit Care Med. 1999 Nov;160(5 Pt 2):S44-8. doi: 10.1164/ajrccm.160.supplement_1.12. Am J Respir Crit Care Med. 1999. PMID: 10556169 Review.
Relatively common, however, is the involvement of the protein tyrosine kinase c-Src, the MAP kinase kinase MEK 1/2, and the transcription factor NF-kappaB. Basbaum C, Lemjabbar H, Longphre M, Li D, Gensch E, McNamara N. Control of mucin transcription by diver …
Relatively common, however, is the involvement of the protein tyrosine kinase c-Src, the MAP kinase kinase MEK 1/2, and the transcrip …
Mucin gene (MUC 2 and MUC 5AC) upregulation by Gram-positive and Gram-negative bacteria.
Dohrman A, Miyata S, Gallup M, Li JD, Chapelin C, Coste A, Escudier E, Nadel J, Basbaum C. Dohrman A, et al. Among authors: basbaum c. Biochim Biophys Acta. 1998 Apr 28;1406(3):251-9. doi: 10.1016/s0925-4439(98)00010-6. Biochim Biophys Acta. 1998. PMID: 9630659
Prince, C. Basbaum, Transcriptional activation of mucin by P. aeruginosa lipopolysaccharide in the pathogenesis of cystic fibrosis lung disease, Proc. ...
Prince, C. Basbaum, Transcriptional activation of mucin by P. aeruginosa lipopolysaccharide in the pathogenesis of cystic fibr …
Activation of NF-kappaB via a Src-dependent Ras-MAPK-pp90rsk pathway is required for Pseudomonas aeruginosa-induced mucin overproduction in epithelial cells.
Li JD, Feng W, Gallup M, Kim JH, Gum J, Kim Y, Basbaum C. Li JD, et al. Among authors: basbaum c. Proc Natl Acad Sci U S A. 1998 May 12;95(10):5718-23. doi: 10.1073/pnas.95.10.5718. Proc Natl Acad Sci U S A. 1998. PMID: 9576950 Free PMC article.
Here we show that P. aeruginosa activates a c-Src-Ras-MEK1/2-MAPK-pp90rsk signaling pathway that leads to activation of nuclear factor NF-kappaB (p65/p50). ...
Here we show that P. aeruginosa activates a c-Src-Ras-MEK1/2-MAPK-pp90rsk signaling pathway that leads to activation of nuclear facto …
Sp1 protein contributes to airway-specific rat MUC 2 mucin gene transcription.
Nogami H, Ohmori H, Li JD, Gallup M, Gum J, Kim Y, Basbaum C. Nogami H, et al. Among authors: basbaum c. Gene. 1997 Oct 1;198(1-2):191-201. doi: 10.1016/s0378-1119(97)00314-4. Gene. 1997. PMID: 9370281
Concurrent increases in the storage and release of mucin-like molecules by rat airway epithelial cells in response to bacterial endotoxin.
Steiger D, Hotchkiss J, Bajaj L, Harkema J, Basbaum C. Steiger D, et al. Among authors: basbaum c. Am J Respir Cell Mol Biol. 1995 Mar;12(3):307-14. doi: 10.1165/ajrcmb.12.3.7873197. Am J Respir Cell Mol Biol. 1995. PMID: 7873197
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