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Directed evolution of gene-shuffled IFN-alpha molecules with activity profiles tailored for treatment of chronic viral diseases.
Brideau-Andersen AD, Huang X, Sun SC, Chen TT, Stark D, Sas IJ, Zadik L, Dawes GN, Guptill DR, McCord R, Govindarajan S, Roy A, Yang S, Gao J, Chen YH, Skartved NJ, Pedersen AK, Lin D, Locher CP, Rebbapragada I, Jensen AD, Bass SH, Nissen TL, Viswanathan S, Foster GR, Symons JA, Patten PA. Brideau-Andersen AD, et al. Among authors: bass sh. Proc Natl Acad Sci U S A. 2007 May 15;104(20):8269-74. doi: 10.1073/pnas.0609001104. Epub 2007 May 9. Proc Natl Acad Sci U S A. 2007. PMID: 17494769 Free PMC article.
ASP2408 and ASP2409, novel CTLA4-Ig variants with CD86-selective ligand binding activity and improved immunosuppressive potency, created by directed evolution.
Oshima S, Karrer EE, Paidhungat MM, Neighbors M, Chapin SJ, Fan RA, Reed MA, Wu K, Wong C, Chen Y, Whitlow M, Anderson FA, Bam RA, Zhang Q, Larsen BR, Viswanathan S, Devens BH, Bass SH, Higashi Y. Oshima S, et al. Among authors: bass sh. Protein Eng Des Sel. 2016 May;29(5):159-67. doi: 10.1093/protein/gzw002. Epub 2016 Mar 10. Protein Eng Des Sel. 2016. PMID: 26968452
Digitally Recording Comfort Observations in the Last Days of Life.
Stewart E, Ford-Dunn S, Bass S, Ede C, Elliott J, Peters D, Caputo R, Moreira L, Savage E, Minton O. Stewart E, et al. Among authors: bass s. Am J Hosp Palliat Care. 2024 Feb 20:10499091241234859. doi: 10.1177/10499091241234859. Online ahead of print. Am J Hosp Palliat Care. 2024. PMID: 38378258
522 results