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Structure engineering of filled protein microbeads to tailor release of oil droplets in gastric digestion.
van Leusden P, den Hartog GJ, Bast A, Postema M, van der Linden E, Sagis LM. van Leusden P, et al. Among authors: bast a. Food Funct. 2016 Aug 10;7(8):3539-47. doi: 10.1039/c6fo00405a. Epub 2016 Jul 26. Food Funct. 2016. PMID: 27458022
Oil-soluble components can be encapsulated in an O/W1/W2 microsystem, in which they are dissolved in oil droplets dispersed in a gelled microbead (W1), which forms a barrier between the oil droplets and the aqueous continuous phase (W2). ...Freeze-drying changed the …
Oil-soluble components can be encapsulated in an O/W1/W2 microsystem, in which they are dissolved in oil droplets dispersed in a gell …
Optimizing the bioactive potential of wheat bran by processing.
Mateo Anson N, Hemery YM, Bast A, Haenen GR. Mateo Anson N, et al. Among authors: bast a. Food Funct. 2012 Apr;3(4):362-75. doi: 10.1039/c2fo10241b. Epub 2012 Feb 15. Food Funct. 2012. PMID: 22336890 Review. No abstract available.
Protection against nitric oxide toxicity by tea.
Paquay JB, Haenen GR, Stender G, Wiseman SA, Tijburg LB, Bast A. Paquay JB, et al. Among authors: bast a. J Agric Food Chem. 2000 Nov;48(11):5768-72. doi: 10.1021/jf981316h. J Agric Food Chem. 2000. PMID: 11087552
Synergistic effects between the compounds, or the presence of a potent, unidentified NO(*) scavenger, may explain the high activity of BTP. ...
Synergistic effects between the compounds, or the presence of a potent, unidentified NO(*) scavenger, may explain the high activity o …
Protection against chemotaxis in the anti-inflammatory effect of bioactives from tomato ketchup.
Hazewindus M, Haenen GR, Weseler AR, Bast A. Hazewindus M, et al. Among authors: bast a. PLoS One. 2014 Dec 31;9(12):e114387. doi: 10.1371/journal.pone.0114387. eCollection 2014. PLoS One. 2014. PMID: 25551565 Free PMC article.
Chemotaxis was effectively impeded as demonstrated by a reduced monocyte migration. This effect correlated with the reduction of IL-8 production in the presence of the test compounds and extracts. ...Such a pleotropic mode of action exemplifies its potential mitigat …
Chemotaxis was effectively impeded as demonstrated by a reduced monocyte migration. This effect correlated with the reduction of IL-8 …
The effect of dietary components on inflammatory lung diseases - a literature review.
de Boer A, van de Worp WRPH, Hageman GJ, Bast A. de Boer A, et al. Among authors: bast a. Int J Food Sci Nutr. 2017 Nov;68(7):771-787. doi: 10.1080/09637486.2017.1288199. Epub 2017 Feb 14. Int J Food Sci Nutr. 2017. PMID: 28276906 Review.
Many other dietary components showed only small or no effects on inflammation and/or lung function, although the number of weighted studies was often too small for a reliable assessment. ...
Many other dietary components showed only small or no effects on inflammation and/or lung function, although the number of weighted studies …
The potential of flavonoids in the treatment of non-alcoholic fatty liver disease.
Van De Wier B, Koek GH, Bast A, Haenen GR. Van De Wier B, et al. Among authors: bast a. Crit Rev Food Sci Nutr. 2017 Mar 4;57(4):834-855. doi: 10.1080/10408398.2014.952399. Crit Rev Food Sci Nutr. 2017. PMID: 25897647 Review.
The contemporary pathophysiological model of non-alcoholic fatty liver disease (NAFLD) comprises multiple parallel pathways with a dynamic cross talk that cumulate in steatosis and inflammation, and ultimately fibrosis, cirrhosis, liver failure, and hepatocellular carcinom …
The contemporary pathophysiological model of non-alcoholic fatty liver disease (NAFLD) comprises multiple parallel pathways with a dy …
Effect of bioprocessing of wheat bran in wholemeal wheat breads on the colonic SCFA production in vitro and postprandial plasma concentrations in men.
Anson NM, Havenaar R, Vaes W, Coulier L, Venema K, Selinheimo E, Bast A, Haenen GR. Anson NM, et al. Among authors: bast a. Food Chem. 2011 Sep 15;128(2):404-9. doi: 10.1016/j.foodchem.2011.03.043. Epub 2011 Mar 21. Food Chem. 2011. PMID: 25212148
A higher in vitro production of butyrate was induced by wholemeal wheat bread with bioprocessed bran than by native bran. The increase in butyrate seemed to be in exchange for propionate, whilst the total SCFA production remained similar. ...
A higher in vitro production of butyrate was induced by wholemeal wheat bread with bioprocessed bran than by native bran. The increas
Competition between ascorbate and glutathione for the oxidized form of methylated quercetin metabolites and analogues: tamarixetin, 4'O-methylquercetin, has the lowest thiol reactivity.
Moalin M, van Strijdonck GP, Bast A, Haenen GR. Moalin M, et al. Among authors: bast a. J Agric Food Chem. 2012 Sep 12;60(36):9292-7. doi: 10.1021/jf302068v. Epub 2012 Aug 27. J Agric Food Chem. 2012. PMID: 22860763
Quercetin (Q) is a bioactive compound with excellent antioxidant activity. However, the thiol reactivity of its oxidation product (oxQ) forms a disadvantage. ...The endogenous metabolism of Q to 4'MQ might be a physiological way to safely benefit from the ant …
Quercetin (Q) is a bioactive compound with excellent antioxidant activity. However, the thiol reactivity of its oxidation product (ox …
Pleiotropic-acting nutrients require integrative investigational approaches: the example of flavonoids.
Weseler AR, Bast A. Weseler AR, et al. Among authors: bast a. J Agric Food Chem. 2012 Sep 12;60(36):8941-6. doi: 10.1021/jf3000373. Epub 2012 Apr 9. J Agric Food Chem. 2012. PMID: 22455609
Assessment of the health effects of dietary interventions in humans poses a particular challenge to nutritional and clinical scientists. ...A critical appraisal of this approach for the future is provided....
Assessment of the health effects of dietary interventions in humans poses a particular challenge to nutritional and clinical scientis …
New insights into controversies on the antioxidant potential of the olive oil antioxidant hydroxytyrosol.
Rietjens SJ, Bast A, Haenen GR. Rietjens SJ, et al. Among authors: bast a. J Agric Food Chem. 2007 Sep 5;55(18):7609-14. doi: 10.1021/jf0706934. Epub 2007 Aug 7. J Agric Food Chem. 2007. PMID: 17683140
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