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Masquelier's grape seed extract: from basic flavonoid research to a well-characterized food supplement with health benefits.
Weseler AR, Bast A. Weseler AR, et al. Among authors: bast a. Nutr J. 2017 Jan 19;16(1):5. doi: 10.1186/s12937-016-0218-1. Nutr J. 2017. PMID: 28103873 Free PMC article. Review.
In this review we follow a specific grape seed extract containing monomeric and oligomeric flavan-3-ols from its creation by Jack Masquelier in 1947 towards a botanical remedy and nutraceutical with proven health benefits. ...Recent clinical data revealed a m …
In this review we follow a specific grape seed extract containing monomeric and oligomeric flavan-3-ols from its creation by Jack Mas …
Chemicals and health - thought for food.
Bast A, Hanekamp JC. Bast A, et al. Dose Response. 2012 Oct 9;11(3):295-300. doi: 10.2203/dose-response.12-031.Hanekamp. eCollection 2012. Dose Response. 2012. PMID: 23983660 Free PMC article.
We show that for some food components such as flavonoids, a whole range of small toxicological effects that have been uncovered the last decade on the whole confer benefits to human health. ...
We show that for some food components such as flavonoids, a whole range of small toxicological effects that have been uncovered the l …
Nutrition and health – transforming research traditions.
Hanekamp JC, Bast A, Calabrese EJ. Hanekamp JC, et al. Among authors: bast a. Crit Rev Food Sci Nutr. 2015;55(8):1074-80. doi: 10.1080/10408398.2012.680525. Crit Rev Food Sci Nutr. 2015. PMID: 24915340 Review.
Increased performance of health, i.e., the maximum stimulation of health, typically seems 30-60% greater than the control group, with a width of no more than about a factor of ten, clarifying the difficulty of documenting responses of food-endogenous components with …
Increased performance of health, i.e., the maximum stimulation of health, typically seems 30-60% greater than the control group, with a
Nutrition and corticosteroids in the treatment of sarcoidosis.
Bast A, Semen KO, Drent M. Bast A, et al. Curr Opin Pulm Med. 2018 Sep;24(5):479-486. doi: 10.1097/MCP.0000000000000501. Curr Opin Pulm Med. 2018. PMID: 29939865 Review.
PURPOSE OF REVIEW: Sarcoidosis is a chronic disease, which is routinely treated with corticosteroids. Steroid resistance or steroid-induced adverse effects require alternatives. ...Several complementing lines of evidence should be integrated in order to be able to advise s …
PURPOSE OF REVIEW: Sarcoidosis is a chronic disease, which is routinely treated with corticosteroids. Steroid resistance or steroid-i …
Antioxidant effects of carotenoids.
Bast A, Haenen GR, van den Berg R, van den Berg H. Bast A, et al. Int J Vitam Nutr Res. 1998;68(6):399-403. Int J Vitam Nutr Res. 1998. PMID: 9857268 Review.
It is concluded that a severe lack of knowledge hampers adequate suggestions for human supplementation....
It is concluded that a severe lack of knowledge hampers adequate suggestions for human supplementation....
Dietary flavanols modulate the transcription of genes associated with cardiovascular pathology without changes in their DNA methylation state.
Milenkovic D, Vanden Berghe W, Boby C, Leroux C, Declerck K, Szarc vel Szic K, Heyninck K, Laukens K, Bizet M, Defrance M, Dedeurwaerder S, Calonne E, Fuks F, Haegeman G, Haenen GR, Bast A, Weseler AR. Milenkovic D, et al. Among authors: bast a. PLoS One. 2014 Apr 24;9(4):e95527. doi: 10.1371/journal.pone.0095527. eCollection 2014. PLoS One. 2014. PMID: 24763279 Free PMC article.
BACKGROUND: In a recent intervention study, the daily supplementation with 200 mg monomeric and oligomeric flavanols (MOF) from grape seeds for 8 weeks revealed a vascular health benefit in male smokers. ...As a consequence, on group level, changes due to MOF …
BACKGROUND: In a recent intervention study, the daily supplementation with 200 mg monomeric and oligomeric flavanols (MOF) from grape …
Acute cocoa Flavanols intake has minimal effects on exercise-induced oxidative stress and nitric oxide production in healthy cyclists: a randomized controlled trial.
Decroix L, Tonoli C, Soares DD, Descat A, Drittij-Reijnders MJ, Weseler AR, Bast A, Stahl W, Heyman E, Meeusen R. Decroix L, et al. Among authors: bast a. J Int Soc Sports Nutr. 2017 Aug 10;14:28. doi: 10.1186/s12970-017-0186-7. eCollection 2017. J Int Soc Sports Nutr. 2017. PMID: 28811749 Free PMC article. Clinical Trial.
The effect of dietary components on inflammatory lung diseases - a literature review.
de Boer A, van de Worp WRPH, Hageman GJ, Bast A. de Boer A, et al. Among authors: bast a. Int J Food Sci Nutr. 2017 Nov;68(7):771-787. doi: 10.1080/09637486.2017.1288199. Epub 2017 Feb 14. Int J Food Sci Nutr. 2017. PMID: 28276906 Review.
Many other dietary components showed only small or no effects on inflammation and/or lung function, although the number of weighted studies was often too small for a reliable assessment. ...
Many other dietary components showed only small or no effects on inflammation and/or lung function, although the number of weighted studies …
Food-Derived Bioactives Can Protect the Anti-Inflammatory Activity of Cortisol with Antioxidant-Dependent and -Independent Mechanisms.
Ruijters EJ, Haenen GR, Willemsen M, Weseler AR, Bast A. Ruijters EJ, et al. Among authors: bast a. Int J Mol Sci. 2016 Feb 15;17(2):239. doi: 10.3390/ijms17020239. Int J Mol Sci. 2016. PMID: 26891295 Free PMC article.
In this exploratory study we screened a broad range of food-derived bioactives for their antioxidant and anti-inflammatory effects in order to investigate whether their antioxidant effects are associated with the ability to preserve the anti-inflammatory effects of cortiso …
In this exploratory study we screened a broad range of food-derived bioactives for their antioxidant and anti-inflammatory effects in …
Ten misconceptions about antioxidants.
Bast A, Haenen GR. Bast A, et al. Trends Pharmacol Sci. 2013 Aug;34(8):430-6. doi: 10.1016/j.tips.2013.05.010. Epub 2013 Jun 24. Trends Pharmacol Sci. 2013. PMID: 23806765 Review.
Owing to the polarity of views towards antioxidants, nutritional recommendation ranges from advice to increase antioxidant status in plasma to the notion that it is a useless measurement. ...As a result, good opportunities might easily be missed....
Owing to the polarity of views towards antioxidants, nutritional recommendation ranges from advice to increase antioxidant status in plasma …
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