Bates D - Search Results

1

Microtubule destabilising agents: far more than just antimitotic anticancer drugs.

Bates D, Eastman A. Bates D, et al. Br J Clin Pharmacol. 2017 Feb;83(2):255-268. doi: 10.1111/bcp.13126. Epub 2016 Oct 18. Br J Clin Pharmacol. 2017. PMID: 27620987 Free PMC article. Review.

2

Rapid induction of apoptosis in chronic lymphocytic leukemia cells by the microtubule disrupting agent BNC105.

Bates D, Feris EJ, Danilov AV, Eastman A. Bates D, et al. Cancer Biol Ther. 2016;17(3):291-9. doi: 10.1080/15384047.2016.1139245. Epub 2016 Jan 30. Cancer Biol Ther. 2016. PMID: 26891146 Free PMC article.

3

Vincristine activates c-Jun N-terminal kinase in chronic lymphocytic leukaemia in vivo.

Bates DJ, Lewis LD, Eastman A, Danilov AV. Bates DJ, et al. Br J Clin Pharmacol. 2015 Sep;80(3):493-501. doi: 10.1111/bcp.12624. Epub 2015 May 19. Br J Clin Pharmacol. 2015. PMID: 25753324 Free PMC article.

4

Strategically Timing Inhibition of Phosphatidylinositol 3-Kinase to Maximize Therapeutic Index in Estrogen Receptor Alpha-Positive, PIK3CA-Mutant Breast Cancer.

Yang W, Hosford SR, Dillon LM, Shee K, Liu SC, Bean JR, Salphati L, Pang J, Zhang X, Nannini MA, Demidenko E, Bates D, Lewis LD, Marotti JD, Eastman AR, Miller TW. Yang W, et al. Among authors: bates d. Clin Cancer Res. 2016 May 1;22(9):2250-60. doi: 10.1158/1078-0432.CCR-15-2276. Epub 2016 Jan 5. Clin Cancer Res. 2016. PMID: 26733612 Free PMC article.

5

Confounding off-target effects of BH3 mimetics at commonly used concentrations: MIM1, UMI-77, and A-1210477.

Mallick DJ, Soderquist RS, Bates D, Eastman A. Mallick DJ, et al. Among authors: bates d. Cell Death Dis. 2019 Feb 22;10(3):185. doi: 10.1038/s41419-019-1426-3. Cell Death Dis. 2019. PMID: 30796196 Free PMC article.

6

Multiple BH3 mimetics antagonize antiapoptotic MCL1 protein by inducing the endoplasmic reticulum stress response and up-regulating BH3-only protein NOXA.

Albershardt TC, Salerni BL, Soderquist RS, Bates DJ, Pletnev AA, Kisselev AF, Eastman A. Albershardt TC, et al. J Biol Chem. 2011 Jul 15;286(28):24882-95. doi: 10.1074/jbc.M111.255828. Epub 2011 May 31. J Biol Chem. 2011. PMID: 21628457 Free PMC article.

7

Vinblastine rapidly induces NOXA and acutely sensitizes primary chronic lymphocytic leukemia cells to ABT-737.

Bates DJ, Danilov AV, Lowrey CH, Eastman A. Bates DJ, et al. Mol Cancer Ther. 2013 Aug;12(8):1504-14. doi: 10.1158/1535-7163.MCT-12-1197. Epub 2013 May 30. Mol Cancer Ther. 2013. PMID: 23723123 Free PMC article.

8

Vinblastine induces acute, cell cycle phase-independent apoptosis in some leukemias and lymphomas and can induce acute apoptosis in others when Mcl-1 is suppressed.

Salerni BL, Bates DJ, Albershardt TC, Lowrey CH, Eastman A. Salerni BL, et al. Mol Cancer Ther. 2010 Apr;9(4):791-802. doi: 10.1158/1535-7163.MCT-10-0028. Epub 2010 Apr 6. Mol Cancer Ther. 2010. PMID: 20371726 Free PMC article.

9

Gossypol overcomes stroma-mediated resistance to the BCL2 inhibitor ABT-737 in chronic lymphocytic leukemia cells ex vivo.

Soderquist R, Bates DJ, Danilov AV, Eastman A. Soderquist R, et al. Among authors: bates dj. Leukemia. 2013 Nov;27(11):2262-4. doi: 10.1038/leu.2013.138. Epub 2013 May 3. Leukemia. 2013. PMID: 23640104 Free PMC article. No abstract available.

10

Vinblastine sensitizes leukemia cells to cyclin-dependent kinase inhibitors, inducing acute cell cycle phase-independent apoptosis.

Bates DJ, Salerni BL, Lowrey CH, Eastman A. Bates DJ, et al. Cancer Biol Ther. 2011 Aug 15;12(4):314-25. doi: 10.4161/cbt.12.4.16909. Epub 2011 Aug 15. Cancer Biol Ther. 2011. PMID: 21768777 Free PMC article.

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