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Five birds, one stone: neutralization of α-hemolysin and 4 bi-component leukocidins of Staphylococcus aureus with a single human monoclonal antibody.
Rouha H, Badarau A, Visram ZC, Battles MB, Prinz B, Magyarics Z, Nagy G, Mirkina I, Stulik L, Zerbs M, Jägerhofer M, Maierhofer B, Teubenbacher A, Dolezilkova I, Gross K, Banerjee S, Zauner G, Malafa S, Zmajkovic J, Maier S, Mabry R, Krauland E, Wittrup KD, Gerngross TU, Nagy E. Rouha H, et al. Among authors: battles mb. MAbs. 2015;7(1):243-54. doi: 10.4161/19420862.2014.985132. MAbs. 2015. PMID: 25523282 Free PMC article.
Context matters: The importance of dimerization-induced conformation of the LukGH leukocidin of Staphylococcus aureus for the generation of neutralizing antibodies.
Badarau A, Rouha H, Malafa S, Battles MB, Walker L, Nielson N, Dolezilkova I, Teubenbacher A, Banerjee S, Maierhofer B, Weber S, Stulik L, Logan DT, Welin M, Mirkina I, Pleban C, Zauner G, Gross K, Jägerhofer M, Magyarics Z, Nagy E. Badarau A, et al. Among authors: battles mb. MAbs. 2016 Oct;8(7):1347-1360. doi: 10.1080/19420862.2016.1215791. Epub 2016 Jul 28. MAbs. 2016. PMID: 27467113 Free PMC article.
Broad and potent activity against SARS-like viruses by an engineered human monoclonal antibody.
Rappazzo CG, Tse LV, Kaku CI, Wrapp D, Sakharkar M, Huang D, Deveau LM, Yockachonis TJ, Herbert AS, Battles MB, O'Brien CM, Brown ME, Geoghegan JC, Belk J, Peng L, Yang L, Hou Y, Scobey TD, Burton DR, Nemazee D, Dye JM, Voss JE, Gunn BM, McLellan JS, Baric RS, Gralinski LE, Walker LM. Rappazzo CG, et al. Among authors: battles mb. Science. 2021 Feb 19;371(6531):823-829. doi: 10.1126/science.abf4830. Epub 2021 Jan 25. Science. 2021. PMID: 33495307 Free PMC article.
Iterative screen optimization maximizes the efficiency of macromolecular crystallization.
Jones HG, Wrapp D, Gilman MSA, Battles MB, Wang N, Sacerdote S, Chuang GY, Kwong PD, McLellan JS. Jones HG, et al. Among authors: battles mb. Acta Crystallogr F Struct Biol Commun. 2019 Feb 1;75(Pt 2):123-131. doi: 10.1107/S2053230X18017338. Epub 2019 Jan 24. Acta Crystallogr F Struct Biol Commun. 2019. PMID: 30713164 Free PMC article.
Respiratory syncytial virus entry and how to block it.
Battles MB, McLellan JS. Battles MB, et al. Nat Rev Microbiol. 2019 Apr;17(4):233-245. doi: 10.1038/s41579-019-0149-x. Nat Rev Microbiol. 2019. PMID: 30723301 Free PMC article. Review.
Alternative conformations of a major antigenic site on RSV F.
Jones HG, Battles MB, Lin CC, Bianchi S, Corti D, McLellan JS. Jones HG, et al. Among authors: battles mb. PLoS Pathog. 2019 Jul 15;15(7):e1007944. doi: 10.1371/journal.ppat.1007944. eCollection 2019 Jul. PLoS Pathog. 2019. PMID: 31306469 Free PMC article.
An Engineered Antibody with Broad Protective Efficacy in Murine Models of SARS and COVID-19.
Rappazzo CG, Tse LV, Kaku CI, Wrapp D, Sakharkar M, Huang D, Deveau LM, Yockachonis TJ, Herbert AS, Battles MB, O'Brien CM, Brown ME, Geoghegan JC, Belk J, Peng L, Yang L, Scobey TD, Burton DR, Nemazee D, Dye JM, Voss JE, Gunn BM, McLellan JS, Baric RS, Gralinski LE, Walker LM. Rappazzo CG, et al. Among authors: battles mb. bioRxiv [Preprint]. 2020 Nov 17:2020.11.17.385500. doi: 10.1101/2020.11.17.385500. bioRxiv. 2020. PMID: 33236009 Free PMC article. Preprint.
17 results