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Blockade of the PD-1/PD-L1 axis augments lysis of AML cells by the CD33/CD3 BiTE antibody construct AMG 330: reversing a T-cell-induced immune escape mechanism.
Krupka C, Kufer P, Kischel R, Zugmaier G, Lichtenegger FS, Köhnke T, Vick B, Jeremias I, Metzeler KH, Altmann T, Schneider S, Fiegl M, Spiekermann K, Bauerle PA, Hiddemann W, Riethmüller G, Subklewe M. Krupka C, et al. Among authors: bauerle pa. Leukemia. 2016 Feb;30(2):484-91. doi: 10.1038/leu.2015.214. Epub 2015 Aug 4. Leukemia. 2016. PMID: 26239198
EpCAM as a target in cancer therapy.
Gires O, Bauerle PA. Gires O, et al. Among authors: bauerle pa. J Clin Oncol. 2010 May 20;28(15):e239-40; author reply e241-2. doi: 10.1200/JCO.2009.26.8540. Epub 2010 Apr 12. J Clin Oncol. 2010. PMID: 20385979 No abstract available.