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Showing results for Bcl-2 functions in and anti oxidant pathway to prevent apoptosis.
Your search for Bcl-2 functions in an anti-oxidant pathway to prevent apoptosis. retrieved no results
Puerarin attenuates neurological deficits via Bcl-2/Bax/cleaved caspase-3 and Sirt3/SOD2 apoptotic pathways in subarachnoid hemorrhage mice.
Zhang Y, Yang X, Ge X, Zhang F. Zhang Y, et al. Biomed Pharmacother. 2019 Jan;109:726-733. doi: 10.1016/j.biopha.2018.10.161. Epub 2018 Nov 5. Biomed Pharmacother. 2019. PMID: 30551525 Free article.
BACKGROUND: Subarachnoid hemorrhage (SAH) results in many brain dysfunctions and the neuroprotective function of puerarin after brain damage has been demonstrated in several studies. ...Then apoptosis neuron rate was detected by TUNEL staining. Western blot was carr …
BACKGROUND: Subarachnoid hemorrhage (SAH) results in many brain dysfunctions and the neuroprotective function of puerarin after brain …
Edaravone dexborneol protects cerebral ischemia reperfusion injury through activating Nrf2/HO-1 signaling pathway in mice.
Xu L, Gao Y, Hu M, Dong Y, Xu J, Zhang J, Lv P. Xu L, et al. Fundam Clin Pharmacol. 2022 Oct;36(5):790-800. doi: 10.1111/fcp.12782. Epub 2022 May 4. Fundam Clin Pharmacol. 2022. PMID: 35470467 Free PMC article.
Edaravone dexborneol is a novel neuroprotective agent consisting of edaravone and borneol. Studies have shown that it has synergistic antioxidant and anti-inflammatory effects. However, whether Edaravone dexborneol stimulates the Nrf2/HO-1 pathway to regulate NADPH …
Edaravone dexborneol is a novel neuroprotective agent consisting of edaravone and borneol. Studies have shown that it has synergistic antiox …
Bcl-2/Bax: a rheostat that regulates an anti-oxidant pathway and cell death.
Korsmeyer SJ, Shutter JR, Veis DJ, Merry DE, Oltvai ZN. Korsmeyer SJ, et al. Semin Cancer Biol. 1993 Dec;4(6):327-32. Semin Cancer Biol. 1993. PMID: 8142617 Review.
Bcl-2 does not appear to influence the generation of oxygen free radicals but does prevent oxidative damage to cellular constituents including lipid membranes. ...Moreover, they demonstrate two potentially oxidation related pathologies: polycystic kidney dise …
Bcl-2 does not appear to influence the generation of oxygen free radicals but does prevent oxidative damage to cellular …
Bcl-2 functions in an antioxidant pathway to prevent apoptosis.
Hockenbery DM, Oltvai ZN, Yin XM, Milliman CL, Korsmeyer SJ. Hockenbery DM, et al. Cell. 1993 Oct 22;75(2):241-51. doi: 10.1016/0092-8674(93)80066-n. Cell. 1993. PMID: 7503812
Bcl-2 did not prevent the cyanide-resistant oxidative burst generated by menadione. ...Following an apoptotic signal, cells sustained progressive lipid peroxidation. Overexpression of Bcl-2 functioned to suppress lipid peroxidation comple …
Bcl-2 did not prevent the cyanide-resistant oxidative burst generated by menadione. ...Following an apoptotic signal, c …
Synthetic Pathways and the Therapeutic Potential of Quercetin and Curcumin.
Hasan AA, Tatarskiy V, Kalinina E. Hasan AA, et al. Int J Mol Sci. 2022 Nov 20;23(22):14413. doi: 10.3390/ijms232214413. Int J Mol Sci. 2022. PMID: 36430891 Free PMC article. Review.
Herein, we analyzed recent data on the synthetic pathways, features, and similarity of the properties of quercetin, as the most famous flavonoid, and curcumin, a representative of curcuminoids that despite their anti-oxidant activity, also have a pro-oxida …
Herein, we analyzed recent data on the synthetic pathways, features, and similarity of the properties of quercetin, as the most famou …
Asiaticoside Prevents Oxidative Stress and Apoptosis in Endothelial Cells by Activating ROS-dependent p53/Bcl-2/Caspase-3 Signaling Pathway.
Liang Z, Chen Y, Gu R, Guo Q, Nie X. Liang Z, et al. Curr Mol Med. 2023;23(10):1116-1129. doi: 10.2174/1566524023666221024120825. Curr Mol Med. 2023. PMID: 36284389
The levels of SOD, NO, MDA, GSH-Px, and ROS were tested. Furthermore, several cell death-related genes and proteins (p53, Bax, Bcl-2 and Caspase-3) were assessed with RT-qPCR and Western blotting. ...CONCLUSION: AC alleviates t-BHP-induced oxidative injury an …
The levels of SOD, NO, MDA, GSH-Px, and ROS were tested. Furthermore, several cell death-related genes and proteins (p53, Bax, Bcl …
Effects of resveratrol on HIF-1alpha/VEGF pathway and apoptosis in vitrified duck ovary transplantation.
Qin Q, Li Z, Liu R, Liu S, Guo M, Zhang M, Wu H, Huang L. Qin Q, et al. Theriogenology. 2023 Oct 15;210:84-93. doi: 10.1016/j.theriogenology.2023.06.037. Epub 2023 Jul 7. Theriogenology. 2023. PMID: 37481978
Samples of the transplanted tissues were examined on days 3- and 9- post transplantation for activation of hypoxia-, antioxidant- and apoptosis-related gene expression and apoptosis. Resveratrol significantly increased expression of VEGF, HIF-1alpha, Nrf2, CAT and …
Samples of the transplanted tissues were examined on days 3- and 9- post transplantation for activation of hypoxia-, antioxidant- and apo …
Dipyridamole ameliorates doxorubicin-induced cardiotoxicity.
Alyasiry E, Janabi A, Hadi N. Alyasiry E, et al. J Med Life. 2022 Sep;15(9):1184-1190. doi: 10.25122/jml-2021-0199. J Med Life. 2022. PMID: 36415530 Free PMC article.
Control group: rats received a natural diet and water. Normal saline group: rats received 0.9% normal saline for two weeks. ...Doxorubicin caused cardiotoxicity as indicated by a significant increase in tumor necrosis factor-alpha, interleukin-6, malondialdehyde, and caspa …
Control group: rats received a natural diet and water. Normal saline group: rats received 0.9% normal saline for two weeks. ...Doxoru …
Eucalyptol alleviates avermectin exposure-induced apoptosis and necroptosis of grass carp hepatocytes by regulating ROS/NLRP3 axis.
Wang K, Liu H, Sun W, Guo J, Jiang Z, Xu S, Miao Z. Wang K, et al. Aquat Toxicol. 2023 Nov;264:106739. doi: 10.1016/j.aquatox.2023.106739. Epub 2023 Oct 30. Aquat Toxicol. 2023. PMID: 37918148 Review.
Meanwhile, the expressions of Caspase-8 and Bcl-2 were significantly decreased upon exposure to Avermectin. ...The above results indicated that eucalyptol alleviated AVM exposure-induced apoptosis and necroptosis of grass carp hepatocytes by regulating the RO …
Meanwhile, the expressions of Caspase-8 and Bcl-2 were significantly decreased upon exposure to Avermectin. ...The above resul …
Sulforaphane and myricetin act synergistically to induce apoptosis in 3T3-L1 adipocytes.
Yao A, Shen Y, Zhang Z, Zou Z, Wang A, Chen S, Zhang H, Chen F, Zhao J, Chen Z, Shan Y, Zhang X. Yao A, et al. Mol Med Rep. 2018 Feb;17(2):2945-2951. doi: 10.3892/mmr.2017.8235. Epub 2017 Dec 11. Mol Med Rep. 2018. PMID: 29257275 Free PMC article.
Compared with the effects of each compound alone, the combination of SFN and Myr synergistically reduced cell viability, induced apoptosis, increased pro-apoptotic Bcl-2 associated X protein expression, decreased anti-apoptotic B-cell lymphoma-2 expres …
Compared with the effects of each compound alone, the combination of SFN and Myr synergistically reduced cell viability, induced apoptosi …
917 results