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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1978 1
1979 1
1983 1
1984 1
1985 3
1986 2
1987 8
1988 8
1989 7
1990 21
1991 46
1992 82
1993 144
1994 201
1995 207
1996 267
1997 291
1998 340
1999 428
2000 409
2001 391
2002 423
2003 528
2004 590
2005 707
2006 806
2007 879
2008 1007
2009 1046
2010 1240
2011 1365
2012 1612
2013 1825
2014 1919
2015 1979
2016 1980
2017 2125
2018 2258
2019 2286
2020 2495
2021 2521
2022 2568
2023 2329
2024 867

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33,234 results

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Page 1
Neurotrophic Factor BDNF, Physiological Functions and Therapeutic Potential in Depression, Neurodegeneration and Brain Cancer.
Colucci-D'Amato L, Speranza L, Volpicelli F. Colucci-D'Amato L, et al. Int J Mol Sci. 2020 Oct 21;21(20):7777. doi: 10.3390/ijms21207777. Int J Mol Sci. 2020. PMID: 33096634 Free PMC article. Review.
Brain-derived neurotrophic factor (BDNF) is one of the most distributed and extensively studied neurotrophins in the mammalian brain. ...BDNF acts as paracrine and autocrine factor, on both pre-synaptic and post-synaptic target sit
Brain-derived neurotrophic factor (BDNF) is one of the most distributed and extensively studied neurotrop
BDNF as a Promising Therapeutic Agent in Parkinson's Disease.
Palasz E, Wysocka A, Gasiorowska A, Chalimoniuk M, Niewiadomski W, Niewiadomska G. Palasz E, et al. Int J Mol Sci. 2020 Feb 10;21(3):1170. doi: 10.3390/ijms21031170. Int J Mol Sci. 2020. PMID: 32050617 Free PMC article. Review.
Brain-derived neurotrophic factor (BDNF) promotes neuroprotection and neuroregeneration. ...Direct delivery of exogenous BDNF into the patient's brain did not relieve the symptoms of disease, nor did attempts to enhance BDNF expres
Brain-derived neurotrophic factor (BDNF) promotes neuroprotection and neuroregeneration. ...Direct delive
BDNF - a key transducer of antidepressant effects.
Björkholm C, Monteggia LM. Björkholm C, et al. Neuropharmacology. 2016 Mar;102:72-9. doi: 10.1016/j.neuropharm.2015.10.034. Epub 2015 Nov 11. Neuropharmacology. 2016. PMID: 26519901 Free PMC article. Review.
How do antidepressants elicit an antidepressant response? Here, we review accumulating evidence that the neurotrophin brain-derived neurotrophic factor (BDNF) serves as a transducer, acting as the link between the antidepressant drug and the neu …
How do antidepressants elicit an antidepressant response? Here, we review accumulating evidence that the neurotrophin brain-derive
The aging hippocampus: interactions between exercise, depression, and BDNF.
Erickson KI, Miller DL, Roecklein KA. Erickson KI, et al. Neuroscientist. 2012 Feb;18(1):82-97. doi: 10.1177/1073858410397054. Epub 2011 Apr 29. Neuroscientist. 2012. PMID: 21531985 Free PMC article. Review.
Although there are multiple paths by which hippocampal deterioration occurs in late life, the authors discuss the evidence that a single nucleotide polymorphism in the brain-derived neurotrophic factor (BDNF) gene and age-related changes in B
Although there are multiple paths by which hippocampal deterioration occurs in late life, the authors discuss the evidence that a single nuc …
NGF and BDNF in pediatrics syndromes.
Ferraguti G, Terracina S, Micangeli G, Lucarelli M, Tarani L, Ceccanti M, Spaziani M, D'Orazi V, Petrella C, Fiore M. Ferraguti G, et al. Neurosci Biobehav Rev. 2023 Feb;145:105015. doi: 10.1016/j.neubiorev.2022.105015. Epub 2022 Dec 21. Neurosci Biobehav Rev. 2023. PMID: 36563920 Review.
Neurotrophins (NTs) as nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF) play multiple roles in different settings including neuronal development, function and survival in both the peripheral and the central nervous s …
Neurotrophins (NTs) as nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF) play …
Exercise and circulating BDNF: Mechanisms of release and implications for the design of exercise interventions.
Walsh JJ, Tschakovsky ME. Walsh JJ, et al. Appl Physiol Nutr Metab. 2018 Nov;43(11):1095-1104. doi: 10.1139/apnm-2018-0192. Epub 2018 May 18. Appl Physiol Nutr Metab. 2018. PMID: 29775542 Review.
Acute bouts of exercise transiently improve cognitive function, while long-term exercise training stimulates brain plasticity, improves brain function, and helps to stave off neurological disease. The action of brain-derived neurotrophic factor (BDN
Acute bouts of exercise transiently improve cognitive function, while long-term exercise training stimulates brain plasticity, improves brai …
GDNF, NGF and BDNF as therapeutic options for neurodegeneration.
Allen SJ, Watson JJ, Shoemark DK, Barua NU, Patel NK. Allen SJ, et al. Pharmacol Ther. 2013 May;138(2):155-75. doi: 10.1016/j.pharmthera.2013.01.004. Epub 2013 Jan 21. Pharmacol Ther. 2013. PMID: 23348013 Review.
Glial cell-derived neurotrophic factor (GDNF), and the neurotrophin nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF) are important for the survival, maintenance and regeneration of specific neuronal pop …
Glial cell-derived neurotrophic factor (GDNF), and the neurotrophin nerve growth factor (NGF) and brain-deriv
Metabolic homeostasis via BDNF and its receptors.
Podyma B, Parekh K, Güler AD, Deppmann CD. Podyma B, et al. Trends Endocrinol Metab. 2021 Jul;32(7):488-499. doi: 10.1016/j.tem.2021.04.005. Epub 2021 May 4. Trends Endocrinol Metab. 2021. PMID: 33958275 Free PMC article. Review.
These signals include conserved meal and adipocyte cues such as glucose and leptin, respectively, in addition to more novel players including brain-derived neurotrophic factor (BDNF). In particular, BDNF's two receptors, tropomyosin relat …
These signals include conserved meal and adipocyte cues such as glucose and leptin, respectively, in addition to more novel players includin …
BDNF Propeptide: A Novel Modulator of Synaptic Plasticity.
Kojima M, Mizui T. Kojima M, et al. Vitam Horm. 2017;104:19-28. doi: 10.1016/bs.vh.2016.11.006. Epub 2017 Jan 25. Vitam Horm. 2017. PMID: 28215295 Review.
One of the most characterized neurotrophic factors is brain-derived neurotrophic factor (BDNF), which regulates neuronal survival and differentiation, and functions in activity-dependent plasticity processes such as long-term potentiation …
One of the most characterized neurotrophic factors is brain-derived neurotrophic factor (BDNF), wh …
Challenges of BDNF-based therapies: From common to rare diseases.
Miranda-Lourenço C, Ribeiro-Rodrigues L, Fonseca-Gomes J, Tanqueiro SR, Belo RF, Ferreira CB, Rei N, Ferreira-Manso M, de Almeida-Borlido C, Costa-Coelho T, Freitas CF, Zavalko S, Mouro FM, Sebastião AM, Xapelli S, Rodrigues TM, Diógenes MJ. Miranda-Lourenço C, et al. Pharmacol Res. 2020 Dec;162:105281. doi: 10.1016/j.phrs.2020.105281. Epub 2020 Nov 5. Pharmacol Res. 2020. PMID: 33161136 Review.
Brain-derived neurotrophic factor (BDNF) possesses diverse biological functions which are mediated by the activation of two main classes of receptors, the tropomyosin-related kinase (Trk) B and the p75 neurotrophin receptor (p75(NTR)). ...We des
Brain-derived neurotrophic factor (BDNF) possesses diverse biological functions which are mediated by the
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