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408 results
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Polycomb CBX7 has a unifying role in cellular lifespan.
Gil J, Bernard D, Martínez D, Beach D. Gil J, et al. Among authors: beach d. Nat Cell Biol. 2004 Jan;6(1):67-72. doi: 10.1038/ncb1077. Epub 2003 Nov 30. Nat Cell Biol. 2004. PMID: 14647293
The senescent methylome and its relationship with cancer, ageing and germline genetic variation in humans.
Lowe R, Overhoff MG, Ramagopalan SV, Garbe JC, Koh J, Stampfer MR, Beach DH, Rakyan VK, Bishop CL. Lowe R, et al. Genome Biol. 2015 Sep 17;16(1):194. doi: 10.1186/s13059-015-0748-4. Genome Biol. 2015. PMID: 26381124 Free PMC article.
Monitoring tumorigenesis and senescence in vivo with a p16(INK4a)-luciferase model.
Burd CE, Sorrentino JA, Clark KS, Darr DB, Krishnamurthy J, Deal AM, Bardeesy N, Castrillon DH, Beach DH, Sharpless NE. Burd CE, et al. Cell. 2013 Jan 17;152(1-2):340-51. doi: 10.1016/j.cell.2012.12.010. Cell. 2013. PMID: 23332765 Free PMC article.
Cellular senescence mediated by p16INK4A-coupled miRNA pathways.
Overhoff MG, Garbe JC, Koh J, Stampfer MR, Beach DH, Bishop CL. Overhoff MG, et al. Nucleic Acids Res. 2014 Feb;42(3):1606-18. doi: 10.1093/nar/gkt1096. Epub 2013 Nov 11. Nucleic Acids Res. 2014. PMID: 24217920 Free PMC article.
Tumour biology: senescence in premalignant tumours.
Collado M, Gil J, Efeyan A, Guerra C, Schuhmacher AJ, Barradas M, Benguría A, Zaballos A, Flores JM, Barbacid M, Beach D, Serrano M. Collado M, et al. Among authors: beach d. Nature. 2005 Aug 4;436(7051):642. doi: 10.1038/436642a. Nature. 2005. PMID: 16079833
Ageing as developmental decay: insights from p16(INK4a.).
Martin N, Beach D, Gil J. Martin N, et al. Among authors: beach d. Trends Mol Med. 2014 Dec;20(12):667-74. doi: 10.1016/j.molmed.2014.09.008. Epub 2014 Sep 30. Trends Mol Med. 2014. PMID: 25277993
Glycolytic enzymes can modulate cellular life span.
Kondoh H, Lleonart ME, Gil J, Wang J, Degan P, Peters G, Martinez D, Carnero A, Beach D. Kondoh H, et al. Among authors: beach d. Cancer Res. 2005 Jan 1;65(1):177-85. Cancer Res. 2005. PMID: 15665293
p16(Ink4a) in melanocyte senescence and differentiation.
Sviderskaya EV, Hill SP, Evans-Whipp TJ, Chin L, Orlow SJ, Easty DJ, Cheong SC, Beach D, DePinho RA, Bennett DC. Sviderskaya EV, et al. Among authors: beach d. J Natl Cancer Inst. 2002 Mar 20;94(6):446-54. doi: 10.1093/jnci/94.6.446. J Natl Cancer Inst. 2002. PMID: 11904317
Immortalization of primary human prostate epithelial cells by c-Myc.
Gil J, Kerai P, Lleonart M, Bernard D, Cigudosa JC, Peters G, Carnero A, Beach D. Gil J, et al. Among authors: beach d. Cancer Res. 2005 Mar 15;65(6):2179-85. doi: 10.1158/0008-5472.CAN-03-4030. Cancer Res. 2005. PMID: 15781629
CBX7 controls the growth of normal and tumor-derived prostate cells by repressing the Ink4a/Arf locus.
Bernard D, Martinez-Leal JF, Rizzo S, Martinez D, Hudson D, Visakorpi T, Peters G, Carnero A, Beach D, Gil J. Bernard D, et al. Among authors: beach d. Oncogene. 2005 Aug 25;24(36):5543-51. doi: 10.1038/sj.onc.1208735. Oncogene. 2005. PMID: 15897876
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