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86 results
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p16INK4A and p19ARF act in overlapping pathways in cellular immortalization.
Carnero A, Hudson JD, Price CM, Beach DH. Carnero A, et al. Nat Cell Biol. 2000 Mar;2(3):148-55. doi: 10.1038/35004020. Nat Cell Biol. 2000. PMID: 10707085
The senescent methylome and its relationship with cancer, ageing and germline genetic variation in humans.
Lowe R, Overhoff MG, Ramagopalan SV, Garbe JC, Koh J, Stampfer MR, Beach DH, Rakyan VK, Bishop CL. Lowe R, et al. Among authors: beach dh. Genome Biol. 2015 Sep 17;16(1):194. doi: 10.1186/s13059-015-0748-4. Genome Biol. 2015. PMID: 26381124 Free PMC article.
Monitoring tumorigenesis and senescence in vivo with a p16(INK4a)-luciferase model.
Burd CE, Sorrentino JA, Clark KS, Darr DB, Krishnamurthy J, Deal AM, Bardeesy N, Castrillon DH, Beach DH, Sharpless NE. Burd CE, et al. Among authors: beach dh. Cell. 2013 Jan 17;152(1-2):340-51. doi: 10.1016/j.cell.2012.12.010. Cell. 2013. PMID: 23332765 Free PMC article.
Cellular senescence mediated by p16INK4A-coupled miRNA pathways.
Overhoff MG, Garbe JC, Koh J, Stampfer MR, Beach DH, Bishop CL. Overhoff MG, et al. Among authors: beach dh. Nucleic Acids Res. 2014 Feb;42(3):1606-18. doi: 10.1093/nar/gkt1096. Epub 2013 Nov 11. Nucleic Acids Res. 2014. PMID: 24217920 Free PMC article.
Glycolytic enzymes can modulate cellular life span.
Kondoh H, Lleonart ME, Gil J, Wang J, Degan P, Peters G, Martinez D, Carnero A, Beach D. Kondoh H, et al. Cancer Res. 2005 Jan 1;65(1):177-85. Cancer Res. 2005. PMID: 15665293
p16(Ink4a) in melanocyte senescence and differentiation.
Sviderskaya EV, Hill SP, Evans-Whipp TJ, Chin L, Orlow SJ, Easty DJ, Cheong SC, Beach D, DePinho RA, Bennett DC. Sviderskaya EV, et al. J Natl Cancer Inst. 2002 Mar 20;94(6):446-54. doi: 10.1093/jnci/94.6.446. J Natl Cancer Inst. 2002. PMID: 11904317
Polycomb CBX7 has a unifying role in cellular lifespan.
Gil J, Bernard D, Martínez D, Beach D. Gil J, et al. Nat Cell Biol. 2004 Jan;6(1):67-72. doi: 10.1038/ncb1077. Epub 2003 Nov 30. Nat Cell Biol. 2004. PMID: 14647293
Immortalization of primary human prostate epithelial cells by c-Myc.
Gil J, Kerai P, Lleonart M, Bernard D, Cigudosa JC, Peters G, Carnero A, Beach D. Gil J, et al. Cancer Res. 2005 Mar 15;65(6):2179-85. doi: 10.1158/0008-5472.CAN-03-4030. Cancer Res. 2005. PMID: 15781629
Myc confers androgen-independent prostate cancer cell growth.
Bernard D, Pourtier-Manzanedo A, Gil J, Beach DH. Bernard D, et al. J Clin Invest. 2003 Dec;112(11):1724-31. doi: 10.1172/JCI19035. J Clin Invest. 2003. PMID: 14660748 Free PMC article.
Primary cilium-dependent and -independent Hedgehog signaling inhibits p16(INK4A).
Bishop CL, Bergin AM, Fessart D, Borgdorff V, Hatzimasoura E, Garbe JC, Stampfer MR, Koh J, Beach DH. Bishop CL, et al. Among authors: beach dh. Mol Cell. 2010 Nov 24;40(4):533-47. doi: 10.1016/j.molcel.2010.10.027. Mol Cell. 2010. PMID: 21095584 Free article.
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