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128 results
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Patched acts catalytically to suppress the activity of Smoothened.
Taipale J, Cooper MK, Maiti T, Beachy PA. Taipale J, et al. Among authors: beachy pa. Nature. 2002 Aug 22;418(6900):892-7. doi: 10.1038/nature00989. Nature. 2002. PMID: 12192414
Secretion and localized transcription suggest a role in positional signaling for products of the segmentation gene hedgehog.
Lee JJ, von Kessler DP, Parks S, Beachy PA. Lee JJ, et al. Among authors: beachy pa. Cell. 1992 Oct 2;71(1):33-50. doi: 10.1016/0092-8674(92)90264-d. Cell. 1992. PMID: 1394430
Drosophila proteins pave the way to gene mutations.
Beachy P. Beachy P. Nature. 1985 Sep 5-11;317(6032):18-9. doi: 10.1038/317018a0. Nature. 1985. PMID: 3929143 No abstract available.
A potential catalytic site revealed by the 1.7-A crystal structure of the amino-terminal signalling domain of Sonic hedgehog.
Hall TM, Porter JA, Beachy PA, Leahy DJ. Hall TM, et al. Among authors: beachy pa. Nature. 1995 Nov 9;378(6553):212-6. doi: 10.1038/378212a0. Nature. 1995. PMID: 7477329
Patterning activities of vertebrate hedgehog proteins in the developing eye and brain.
Ekker SC, Ungar AR, Greenstein P, von Kessler DP, Porter JA, Moon RT, Beachy PA. Ekker SC, et al. Among authors: beachy pa. Curr Biol. 1995 Aug 1;5(8):944-55. doi: 10.1016/s0960-9822(95)00185-0. Curr Biol. 1995. PMID: 7583153
Distinct expression and shared activities of members of the hedgehog gene family of Xenopus laevis.
Ekker SC, McGrew LL, Lai CJ, Lee JJ, von Kessler DP, Moon RT, Beachy PA. Ekker SC, et al. Among authors: beachy pa. Development. 1995 Aug;121(8):2337-47. Development. 1995. PMID: 7671800
Products, genetic linkage and limb patterning activity of a murine hedgehog gene.
Chang DT, López A, von Kessler DP, Chiang C, Simandl BK, Zhao R, Seldin MF, Fallon JF, Beachy PA. Chang DT, et al. Among authors: beachy pa. Development. 1994 Nov;120(11):3339-53. Development. 1994. PMID: 7720571
Floor plate and motor neuron induction by different concentrations of the amino-terminal cleavage product of sonic hedgehog autoproteolysis.
Roelink H, Porter JA, Chiang C, Tanabe Y, Chang DT, Beachy PA, Jessell TM. Roelink H, et al. Among authors: beachy pa. Cell. 1995 May 5;81(3):445-55. doi: 10.1016/0092-8674(95)90397-6. Cell. 1995. PMID: 7736596
Long-range sclerotome induction by sonic hedgehog: direct role of the amino-terminal cleavage product and modulation by the cyclic AMP signaling pathway.
Fan CM, Porter JA, Chiang C, Chang DT, Beachy PA, Tessier-Lavigne M. Fan CM, et al. Among authors: beachy pa. Cell. 1995 May 5;81(3):457-65. doi: 10.1016/0092-8674(95)90398-4. Cell. 1995. PMID: 7736597
Expression of a novel Toll-like gene spans the parasegment boundary and contributes to hedgehog function in the adult eye of Drosophila.
Chiang C, Beachy PA. Chiang C, et al. Among authors: beachy pa. Mech Dev. 1994 Sep;47(3):225-39. doi: 10.1016/0925-4773(94)90041-8. Mech Dev. 1994. PMID: 7848870
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