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Hedgehog signaling restrains bladder cancer progression by eliciting stromal production of urothelial differentiation factors.
Shin K, Lim A, Zhao C, Sahoo D, Pan Y, Spiekerkoetter E, Liao JC, Beachy PA. Shin K, et al. Cancer Cell. 2014 Oct 13;26(4):521-33. doi: 10.1016/j.ccell.2014.09.001. Cancer Cell. 2014. PMID: 25314078 Free PMC article.
The mode of Hedgehog binding to Ihog homologues is not conserved across different phyla.
McLellan JS, Zheng X, Hauk G, Ghirlando R, Beachy PA, Leahy DJ. McLellan JS, et al. Nature. 2008 Oct 16;455(7215):979-83. doi: 10.1038/nature07358. Epub 2008 Sep 14. Nature. 2008. PMID: 18794898 Free PMC article.
Molecular mechanisms of Sonic hedgehog mutant effects in holoprosencephaly.
Maity T, Fuse N, Beachy PA. Maity T, et al. Proc Natl Acad Sci U S A. 2005 Nov 22;102(47):17026-31. doi: 10.1073/pnas.0507848102. Epub 2005 Nov 10. Proc Natl Acad Sci U S A. 2005. PMID: 16282375 Free PMC article.
Hedgehog signalling in prostate regeneration, neoplasia and metastasis.
Karhadkar SS, Bova GS, Abdallah N, Dhara S, Gardner D, Maitra A, Isaacs JT, Berman DM, Beachy PA. Karhadkar SS, et al. Nature. 2004 Oct 7;431(7009):707-12. doi: 10.1038/nature02962. Epub 2004 Sep 12. Nature. 2004. PMID: 15361885
The Hedgehog response network: sensors, switches, and routers.
Lum L, Beachy PA. Lum L, et al. Science. 2004 Jun 18;304(5678):1755-9. doi: 10.1126/science.1098020. Science. 2004. PMID: 15205520 Review.
Novel lipid modifications of secreted protein signals.
Mann RK, Beachy PA. Mann RK, et al. Annu Rev Biochem. 2004;73:891-923. doi: 10.1146/annurev.biochem.73.011303.073933. Annu Rev Biochem. 2004. PMID: 15189162 Review.
Roles for Hedgehog signaling in androgen production and prostate ductal morphogenesis.
Berman DM, Desai N, Wang X, Karhadkar SS, Reynon M, Abate-Shen C, Beachy PA, Shen MM. Berman DM, et al. Dev Biol. 2004 Mar 15;267(2):387-98. doi: 10.1016/j.ydbio.2003.11.018. Dev Biol. 2004. PMID: 15013801
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