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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1976 2
1978 2
1979 2
1982 2
1983 4
1984 2
1985 1
1986 1
1987 3
1988 4
1989 2
1990 4
1992 1
1993 4
1994 3
1995 6
1996 4
1997 2
1998 3
1999 1
2000 2
2001 4
2003 3
2004 1
2005 3
2006 6
2007 6
2008 5
2009 5
2010 1
2011 5
2012 7
2013 6
2014 5
2015 4
2016 4
2017 8
2018 4
2019 2
2020 10
2021 11
2022 17
2023 11
2024 15

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182 results

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Page 1
Structure-Based Discovery of a Series of Covalent, Orally Bioavailable, and Selective BFL1 Inhibitors.
Palisse A, Cheung T, Blokhuis A, Cogswell T, Martins BS, Riemens R, Schellekens R, Battocchio G, Jansen C, Cottee MA, Ornell K, Sacchetto C, Leon L, van Hoek-Emmelot M, Bostock M, Brauer BL, Beaumont K, Lucas SCC, Ahmed S, Blackwell JH, Börjesson U, Gohlke A, Gramatikov IMT, Hargreaves D, van Hoeven V, Kantae V, Kupcova L, Milbradt AG, Seneviratne U, Su N, Vales J, Wang H, White MJ, Kinzel O. Palisse A, et al. Among authors: beaumont k. J Med Chem. 2024 Dec 6. doi: 10.1021/acs.jmedchem.4c01995. Online ahead of print. J Med Chem. 2024. PMID: 39641779
Structure-Based Optimization of a Series of Covalent, Cell Active Bfl-1 Inhibitors.
Lucas SCC, Blackwell JH, Börjesson U, Hargreaves D, Milbradt AG, Bostock MJ, Ahmed S, Beaumont K, Cheung T, Demanze S, Gohlke A, Guerot C, Haider A, Kantae V, Kauffman GW, Kinzel O, Kupcova L, Lainchbury MD, Lamb ML, Leon L, Palisse A, Sacchetto C, Storer RI, Su N, Thomson C, Vales J, Chen Y, Hu X. Lucas SCC, et al. Among authors: beaumont k. J Med Chem. 2024 Sep 26;67(18):16455-16479. doi: 10.1021/acs.jmedchem.4c01288. Epub 2024 Sep 18. J Med Chem. 2024. PMID: 39291659
HLA-E and NKG2A Mediate Resistance to M. bovis BCG Immunotherapy in Non-Muscle-Invasive Bladder Cancer.
Ranti D, Yu H, Wang YA, Bieber C, Strandgaard T, Salomé B, Houghton S, Kim J, Ravichandran H, Okulate I, Merritt E, Bang S, Demetriou A, Li Z, Lindskrog SV, Ruan DF, Daza J, Rai R, Hegewisch-Solloa E, Mace EM, Fernandez-Rodriguez R, Izadmehr S, Doherty G, Narasimhan A, Farkas AM, Cruz-Encarnacion P, Shroff S, Patel F, Tran M, Park SJ, Qi J, Patel M, Geanon D, Kelly G, de Real RM, Lee B, Nie K, Miake-Iye S, Angeliadis K, Radkevich E, Thin TH, Garcia-Barros M, Brown H, Martin B, Mateo A, Soto A, Sussman R, Shiwlani S, Francisco-Simon S, Beaumont KG, Hu Y, Wang YC, Wang L, Sebra RP, Smith S, Skobe M, Clancy-Thompson E, Palmer D, Hammond S, Hopkins BD, Wiklund P, Zhu J, Bravo-Cordero JJ, Brody R, Hopkins B, Chen Z, Kim-Schulze S, Dyrskjøt L, Elemento O, Tocheva A, Song WM, Bhardwaj N, Galsky MD, Sfakianos JP, Horowitz A. Ranti D, et al. Among authors: beaumont kg. bioRxiv [Preprint]. 2024 Sep 3:2024.09.02.610816. doi: 10.1101/2024.09.02.610816. bioRxiv. 2024. PMID: 39282294 Free PMC article. Preprint.
Multiscale mapping of transcriptomic signatures for cardiotoxic drugs.
Hansen J, Xiong Y, Siddiq MM, Dhanan P, Hu B, Shewale B, Yadaw AS, Jayaraman G, Tolentino RE, Chen Y, Martinez P, Beaumont KG, Sebra R, Vidovic D, Schürer SC, Goldfarb J, Gallo JM, Birtwistle MR, Sobie EA, Azeloglu EU, Berger SI, Chan A, Schaniel C, Dubois NC, Iyengar R. Hansen J, et al. Among authors: beaumont kg. Nat Commun. 2024 Sep 11;15(1):7968. doi: 10.1038/s41467-024-52145-4. Nat Commun. 2024. PMID: 39261481 Free PMC article.
Sex-specific role of high-fat diet and stress on behavior, energy metabolism, and the ventromedial hypothalamus.
Shetty S, Duesman SJ, Patel S, Huynh P, Toh P, Shroff S, Das A, Chowhan D, Keller B, Alvarez J, Fisher-Foye R, Sebra R, Beaumont K, McAlpine CS, Rajbhandari P, Rajbhandari AK. Shetty S, et al. Among authors: beaumont k. Biol Sex Differ. 2024 Jul 15;15(1):55. doi: 10.1186/s13293-024-00628-w. Biol Sex Differ. 2024. PMID: 39010139 Free PMC article.
Single-Cell View of Tumor Microenvironment Gradients in Pleural Mesothelioma.
Giotti B, Dolasia K, Zhao W, Cai P, Sweeney R, Merritt E, Kiner E, Kim GS, Bhagwat A, Nguyen T, Hegde S, Fitzgerald BG, Shroff S, Dawson T, Garcia-Barros M, Abdul-Ghafar J, Chen R, Gnjatic S, Soto A, Brody R, Kim-Schulze S, Chen Z, Beaumont KG, Merad M, Flores RM, Sebra RP, Horowitz A, Marron TU, Tocheva A, Wolf A, Tsankov AM. Giotti B, et al. Among authors: beaumont kg. Cancer Discov. 2024 Nov 1;14(11):2262-2278. doi: 10.1158/2159-8290.CD-23-0017. Cancer Discov. 2024. PMID: 38959428
Urine scRNAseq reveals new insights into the bladder tumor immune microenvironment.
Tran MA, Youssef D, Shroff S, Chowhan D, Beaumont KG, Sebra R, Mehrazin R, Wiklund P, Lin JJ, Horowitz A, Farkas AM, Galsky MD, Sfakianos JP, Bhardwaj N. Tran MA, et al. Among authors: beaumont kg. J Exp Med. 2024 Aug 5;221(8):e20240045. doi: 10.1084/jem.20240045. Epub 2024 Jun 7. J Exp Med. 2024. PMID: 38847806 Free PMC article.
A master regulator of opioid reward in the ventral prefrontal cortex.
Smith ACW, Ghoshal S, Centanni SW, Heyer MP, Corona A, Wills L, Andraka E, Lei Y, O'Connor RM, Caligiuri SPB, Khan S, Beaumont K, Sebra RP, Kieffer BL, Winder DG, Ishikawa M, Kenny PJ. Smith ACW, et al. Among authors: beaumont k. Science. 2024 Jun 7;384(6700):eadn0886. doi: 10.1126/science.adn0886. Epub 2024 Jun 7. Science. 2024. PMID: 38843332 Free PMC article.
Single-cell transcriptomic-informed deconvolution of bulk data identifies immune checkpoint blockade resistance in urothelial cancer.
Wang L, Izadmehr S, Sfakianos JP, Tran M, Beaumont KG, Brody R, Cordon-Cardo C, Horowitz A, Sebra R, Oh WK, Bhardwaj N, Galsky MD, Zhu J. Wang L, et al. Among authors: beaumont kg. iScience. 2024 May 7;27(6):109928. doi: 10.1016/j.isci.2024.109928. eCollection 2024 Jun 21. iScience. 2024. PMID: 38812546 Free PMC article.
182 results