Bechthold A - Search Results

1

Crystal structure of the avilamycin resistance-conferring methyltransferase AviRa from Streptomyces viridochromogenes.

Mosbacher TG, Bechthold A, Schulz GE. Mosbacher TG, et al. Among authors: bechthold a. J Mol Biol. 2003 May 23;329(1):147-57. doi: 10.1016/s0022-2836(03)00407-8. J Mol Biol. 2003. PMID: 12742024

2

Structure and function of the antibiotic resistance-mediating methyltransferase AviRb from Streptomyces viridochromogenes.

Mosbacher TG, Bechthold A, Schulz GE. Mosbacher TG, et al. Among authors: bechthold a. J Mol Biol. 2005 Jan 21;345(3):535-45. doi: 10.1016/j.jmb.2004.10.051. J Mol Biol. 2005. PMID: 15581897

3

Structure and action of the C-C bond-forming glycosyltransferase UrdGT2 involved in the biosynthesis of the antibiotic urdamycin.

Mittler M, Bechthold A, Schulz GE. Mittler M, et al. Among authors: bechthold a. J Mol Biol. 2007 Sep 7;372(1):67-76. doi: 10.1016/j.jmb.2007.06.005. Epub 2007 Jun 9. J Mol Biol. 2007. PMID: 17640665

4

The avilamycin resistance determinants AviRa and AviRb methylate 23S rRNA at the guanosine 2535 base and the uridine 2479 ribose.

Treede I, Jakobsen L, Kirpekar F, Vester B, Weitnauer G, Bechthold A, Douthwaite S. Treede I, et al. Among authors: bechthold a. Mol Microbiol. 2003 Jul;49(2):309-18. doi: 10.1046/j.1365-2958.2003.03558.x. Mol Microbiol. 2003. PMID: 12828631 Free article.

5

Novel avilamycin derivatives with improved polarity generated by targeted gene disruption.

Weitnauer G, Hauser G, Hofmann C, Linder U, Boll R, Pelz K, Glaser SJ, Bechthold A. Weitnauer G, et al. Among authors: bechthold a. Chem Biol. 2004 Oct;11(10):1403-11. doi: 10.1016/j.chembiol.2004.08.016. Chem Biol. 2004. PMID: 15489167

6

Biosynthesis of the orthosomycin antibiotic avilamycin A: deductions from the molecular analysis of the avi biosynthetic gene cluster of Streptomyces viridochromogenes Tü57 and production of new antibiotics.

Weitnauer G, Mühlenweg A, Trefzer A, Hoffmeister D, Süssmuth RD, Jung G, Welzel K, Vente A, Girreser U, Bechthold A. Weitnauer G, et al. Among authors: bechthold a. Chem Biol. 2001 Jun;8(6):569-81. doi: 10.1016/s1074-5521(01)00040-0. Chem Biol. 2001. PMID: 11410376

7

Analysis of a C-methyltransferase gene (aviG1) involved in avilamycin biosynthesis in Streptomyces viridochromogenes Tü57 and complementation of a Saccharopolyspora erythraea eryBIII mutant by aviG1.

Weitnauer G, Gaisser S, Kellenberger L, Leadlay PF, Bechthold A. Weitnauer G, et al. Among authors: bechthold a. Microbiology (Reading). 2002 Feb;148(Pt 2):373-379. doi: 10.1099/00221287-148-2-373. Microbiology (Reading). 2002. PMID: 11832501 Free article.

8

An ATP-binding cassette transporter and two rRNA methyltransferases are involved in resistance to avilamycin in the producer organism Streptomyces viridochromogenes Tü57.

Weitnauer G, Gaisser S, Trefzer A, Stockert S, Westrich L, Quiros LM, Mendez C, Salas JA, Bechthold A. Weitnauer G, et al. Among authors: bechthold a. Antimicrob Agents Chemother. 2001 Mar;45(3):690-5. doi: 10.1128/AAC.45.3.690-695.2001. Antimicrob Agents Chemother. 2001. PMID: 11181344 Free PMC article.

9

Genes encoding enzymes responsible for biosynthesis of L-lyxose and attachment of eurekanate during avilamycin biosynthesis.

Hofmann C, Boll R, Heitmann B, Hauser G, Dürr C, Frerich A, Weitnauer G, Glaser SJ, Bechthold A. Hofmann C, et al. Among authors: bechthold a. Chem Biol. 2005 Oct;12(10):1137-43. doi: 10.1016/j.chembiol.2005.08.016. Chem Biol. 2005. PMID: 16242656

10

Two sequence elements of glycosyltransferases involved in urdamycin biosynthesis are responsible for substrate specificity and enzymatic activity.

Hoffmeister D, Ichinose K, Bechthold A. Hoffmeister D, et al. Among authors: bechthold a. Chem Biol. 2001 Jun;8(6):557-67. doi: 10.1016/s1074-5521(01)00039-4. Chem Biol. 2001. PMID: 11410375

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