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Cdx2 initiates histodifferentiation of the midgut endoderm.
Stringer EJ, Pritchard CA, Beck F. Stringer EJ, et al. FEBS Lett. 2008 Jul 23;582(17):2555-60. doi: 10.1016/j.febslet.2008.06.024. Epub 2008 Jun 23. FEBS Lett. 2008. PMID: 18577384
The Cdx2 homeobox gene suppresses intestinal tumorigenesis through non-cell-autonomous mechanisms.
Balbinot C, Armant O, Elarouci N, Marisa L, Martin E, De Clara E, Onea A, Deschamps J, Beck F, Freund JN, Duluc I. Balbinot C, et al. J Exp Med. 2018 Mar 5;215(3):911-926. doi: 10.1084/jem.20170934. Epub 2018 Feb 8. J Exp Med. 2018. PMID: 29439001 Free PMC article.
Fine-tuning and autoregulation of the intestinal determinant and tumor suppressor homeobox gene CDX2 by alternative splicing.
Balbinot C, Vanier M, Armant O, Nair A, Penichon J, Soret C, Martin E, Saandi T, Reimund JM, Deschamps J, Beck F, Domon-Dell C, Gross I, Duluc I, Freund JN. Balbinot C, et al. Cell Death Differ. 2017 Dec;24(12):2173-2186. doi: 10.1038/cdd.2017.140. Epub 2017 Sep 1. Cell Death Differ. 2017. PMID: 28862703 Free PMC article.
Transformation of intestinal stem cells into gastric stem cells on loss of transcription factor Cdx2.
Simmini S, Bialecka M, Huch M, Kester L, van de Wetering M, Sato T, Beck F, van Oudenaarden A, Clevers H, Deschamps J. Simmini S, et al. Nat Commun. 2014 Dec 11;5:5728. doi: 10.1038/ncomms6728. Nat Commun. 2014. PMID: 25500896 Free PMC article.
Multiple regulatory regions control the complex expression pattern of the mouse Cdx2 homeobox gene.
Benahmed F, Gross I, Gaunt SJ, Beck F, Jehan F, Domon-Dell C, Martin E, Kedinger M, Freund JN, Duluc I. Benahmed F, et al. Gastroenterology. 2008 Oct;135(4):1238-1247, 1247.e1-3. doi: 10.1053/j.gastro.2008.06.045. Epub 2008 Jun 25. Gastroenterology. 2008. PMID: 18655789
The role of Cdx genes in the gut and in axial development.
Beck F, Stringer EJ. Beck F, et al. Biochem Soc Trans. 2010 Apr;38(2):353-7. doi: 10.1042/BST0380353. Biochem Soc Trans. 2010. PMID: 20298182 Review.
Cdx2 contributes to the expansion of the early primordial germ cell population in the mouse.
Bialecka M, Young T, Chuva de Sousa Lopes S, ten Berge D, Sanders A, Beck F, Deschamps J. Bialecka M, et al. Dev Biol. 2012 Nov 15;371(2):227-34. doi: 10.1016/j.ydbio.2012.08.018. Epub 2012 Aug 30. Dev Biol. 2012. PMID: 22960234
Cdx2 determines the fate of postnatal intestinal endoderm.
Stringer EJ, Duluc I, Saandi T, Davidson I, Bialecka M, Sato T, Barker N, Clevers H, Pritchard CA, Winton DJ, Wright NA, Freund JN, Deschamps J, Beck F. Stringer EJ, et al. Development. 2012 Feb;139(3):465-74. doi: 10.1242/dev.070722. Epub 2011 Dec 21. Development. 2012. PMID: 22190642 Free PMC article.
A study of regional gut endoderm potency by analysis of Cdx2 null mutant chimaeric mice.
Beck F, Chawengsaksophak K, Luckett J, Giblett S, Tucci J, Brown J, Poulsom R, Jeffery R, Wright NA. Beck F, et al. Dev Biol. 2003 Mar 15;255(2):399-406. doi: 10.1016/s0012-1606(02)00096-9. Dev Biol. 2003. PMID: 12648499
Cdx2 is essential for axial elongation in mouse development.
Chawengsaksophak K, de Graaff W, Rossant J, Deschamps J, Beck F. Chawengsaksophak K, et al. Proc Natl Acad Sci U S A. 2004 May 18;101(20):7641-5. doi: 10.1073/pnas.0401654101. Epub 2004 May 10. Proc Natl Acad Sci U S A. 2004. PMID: 15136723 Free PMC article.
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