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Gigantism and acromegaly due to Xq26 microduplications and GPR101 mutation.
Trivellin G, Daly AF, Faucz FR, Yuan B, Rostomyan L, Larco DO, Schernthaner-Reiter MH, Szarek E, Leal LF, Caberg JH, Castermans E, Villa C, Dimopoulos A, Chittiboina P, Xekouki P, Shah N, Metzger D, Lysy PA, Ferrante E, Strebkova N, Mazerkina N, Zatelli MC, Lodish M, Horvath A, de Alexandre RB, Manning AD, Levy I, Keil MF, Sierra Mde L, Palmeira L, Coppieters W, Georges M, Naves LA, Jamar M, Bours V, Wu TJ, Choong CS, Bertherat J, Chanson P, Kamenick√Ĺ P, Farrell WE, Barlier A, Quezado M, Bjelobaba I, Stojilkovic SS, Wess J, Costanzi S, Liu P, Lupski JR, Beckers A, Stratakis CA. Trivellin G, et al. Among authors: Beckers A. N Engl J Med. 2014 Dec 18;371(25):2363-74. doi: 10.1056/NEJMoa1408028. Epub 2014 Dec 3. N Engl J Med. 2014. PMID: 25470569 Free PMC article.
Clinical and genetic characterization of pituitary gigantism: an international collaborative study in 208 patients.
Rostomyan L, Daly AF, Petrossians P, Nachev E, Lila AR, Lecoq AL, Lecumberri B, Trivellin G, Salvatori R, Moraitis AG, Holdaway I, Kranenburg-van Klaveren DJ, Chiara Zatelli M, Palacios N, Nozieres C, Zacharin M, Ebeling T, Ojaniemi M, Rozhinskaya L, Verrua E, Jaffrain-Rea ML, Filipponi S, Gusakova D, Pronin V, Bertherat J, Belaya Z, Ilovayskaya I, Sahnoun-Fathallah M, Sievers C, Stalla GK, Castermans E, Caberg JH, Sorkina E, Auriemma RS, Mittal S, Kareva M, Lysy PA, Emy P, De Menis E, Choong CS, Mantovani G, Bours V, De Herder W, Brue T, Barlier A, Neggers SJ, Zacharieva S, Chanson P, Shah NS, Stratakis CA, Naves LA, Beckers A. Rostomyan L, et al. Among authors: Beckers A. Endocr Relat Cancer. 2015 Oct;22(5):745-57. doi: 10.1530/ERC-15-0320. Epub 2015 Jul 17. Endocr Relat Cancer. 2015. PMID: 26187128 Free PMC article. Clinical Trial.
AIP mutations and gigantism.
Rostomyan L, Potorac I, Beckers P, Daly AF, Beckers A. Rostomyan L, et al. Among authors: Beckers P, Beckers A. Ann Endocrinol (Paris). 2017 Jun;78(2):123-130. doi: 10.1016/j.ando.2017.04.012. Epub 2017 May 5. Ann Endocrinol (Paris). 2017. PMID: 28483363 Review.
Characterization of GPR101 transcript structure and expression patterns.
Trivellin G, Bjelobaba I, Daly AF, Larco DO, Palmeira L, Faucz FR, Thiry A, Leal LF, Rostomyan L, Quezado M, Schernthaner-Reiter MH, Janjic MM, Villa C, Wu TJ, Stojilkovic SS, Beckers A, Feldman B, Stratakis CA. Trivellin G, et al. Among authors: Beckers A. J Mol Endocrinol. 2016 Aug;57(2):97-111. doi: 10.1530/JME-16-0045. Epub 2016 Jun 9. J Mol Endocrinol. 2016. PMID: 27282544 Free PMC article.
Gigantism Remains a Clinical Challenge.
Daly AF, Beckers A. Daly AF, et al. Among authors: Beckers A. Arch Iran Med. 2015 Dec;18(12):871. Arch Iran Med. 2015. PMID: 26621024 No abstract available.
X-linked acrogigantism syndrome: clinical profile and therapeutic responses.
Beckers A, Lodish MB, Trivellin G, Rostomyan L, Lee M, Faucz FR, Yuan B, Choong CS, Caberg JH, Verrua E, Naves LA, Cheetham TD, Young J, Lysy PA, Petrossians P, Cotterill A, Shah NS, Metzger D, Castermans E, Ambrosio MR, Villa C, Strebkova N, Mazerkina N, Gaillard S, Barra GB, Casulari LA, Neggers SJ, Salvatori R, Jaffrain-Rea ML, Zacharin M, Santamaria BL, Zacharieva S, Lim EM, Mantovani G, Zatelli MC, Collins MT, Bonneville JF, Quezado M, Chittiboina P, Oldfield EH, Bours V, Liu P, W de Herder W, Pellegata N, Lupski JR, Daly AF, Stratakis CA. Beckers A, et al. Endocr Relat Cancer. 2015 Jun;22(3):353-67. doi: 10.1530/ERC-15-0038. Epub 2015 Feb 24. Endocr Relat Cancer. 2015. PMID: 25712922 Free PMC article.
Pituitary gigantism: Causes and clinical characteristics.
Rostomyan L, Daly AF, Beckers A. Rostomyan L, et al. Among authors: Beckers A. Ann Endocrinol (Paris). 2015 Dec;76(6):643-9. doi: 10.1016/j.ando.2015.10.002. Epub 2015 Nov 14. Ann Endocrinol (Paris). 2015. PMID: 26585365 Review.
The causes and consequences of pituitary gigantism.
Beckers A, Petrossians P, Hanson J, Daly AF. Beckers A, et al. Nat Rev Endocrinol. 2018 Dec;14(12):705-720. doi: 10.1038/s41574-018-0114-1. Nat Rev Endocrinol. 2018. PMID: 30361628 Review.
X-LAG: How did they grow so tall?
Beckers A, Rostomyan L, Potorac I, Beckers P, Daly AF. Beckers A, et al. Among authors: Beckers P. Ann Endocrinol (Paris). 2017 Jun;78(2):131-136. doi: 10.1016/j.ando.2017.04.013. Epub 2017 Apr 27. Ann Endocrinol (Paris). 2017. PMID: 28457479 Review.
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