Beckley J - Search Results

1

Prevalence of tick-borne pathogens in Ixodes scapularis in a rural New Jersey County.

Varde S, Beckley J, Schwartz I. Varde S, et al. Among authors: beckley j. Emerg Infect Dis. 1998 Jan-Mar;4(1):97-9. doi: 10.3201/eid0401.980113. Emerg Infect Dis. 1998. PMID: 9452402 Free PMC article.

2

Re-expression of detachment-inducible chloride channel mCLCA5 suppresses growth of metastatic breast cancer cells.

Beckley JR, Pauli BU, Elble RC. Beckley JR, et al. J Biol Chem. 2004 Oct 1;279(40):41634-41. doi: 10.1074/jbc.M408334200. Epub 2004 Jul 30. J Biol Chem. 2004. PMID: 15292178 Free article.

3

Pharmacological characterization of SAGE-718, a novel positive allosteric modulator of N-methyl-d-aspartate receptors.

Beckley JT, Aman TK, Ackley MA, Kazdoba TM, Lewis MC, Smith AC, Farley BJ, Dai J, Deats W, Hoffmann E, Robichaud AJ, Doherty JJ, Quirk MC. Beckley JT, et al. Br J Pharmacol. 2024 Apr;181(7):1028-1050. doi: 10.1111/bph.16235. Epub 2023 Nov 13. Br J Pharmacol. 2024. PMID: 37698384

4

Novel neuroactive steroids as positive allosteric modulators of NMDA receptors: mechanism, site of action, and rescue pharmacology on GRIN variants associated with neurological conditions.

Tang W, Beckley JT, Zhang J, Song R, Xu Y, Kim S, Quirk MC, Robichaud AJ, Diaz ES, Myers SJ, Doherty JJ, Ackley MA, Traynelis SF, Yuan H. Tang W, et al. Among authors: beckley jt. Cell Mol Life Sci. 2023 Jan 16;80(2):42. doi: 10.1007/s00018-022-04667-7. Cell Mol Life Sci. 2023. PMID: 36645496 Free PMC article.

5

Discovery of Selective Inhibitors of Na_V1.7 Templated on Saxitoxin as Therapeutics for Pain.

Pajouhesh H, Delwig A, Beckley JT, Klas S, Monteleone D, Zhou X, Luu G, Du Bois J, Hunter JC, Mulcahy JV. Pajouhesh H, et al. Among authors: beckley jt. ACS Med Chem Lett. 2022 Oct 18;13(11):1763-1768. doi: 10.1021/acsmedchemlett.2c00378. eCollection 2022 Nov 10. ACS Med Chem Lett. 2022. PMID: 36385936 Free PMC article.

6

SAGE-718: A First-in-Class N-Methyl-d-Aspartate Receptor Positive Allosteric Modulator for the Potential Treatment of Cognitive Impairment.

Hill MD, Blanco MJ, Salituro FG, Bai Z, Beckley JT, Ackley MA, Dai J, Doherty JJ, Harrison BL, Hoffmann EC, Kazdoba TM, Lanzetta D, Lewis M, Quirk MC, Robichaud AJ. Hill MD, et al. Among authors: beckley jt. J Med Chem. 2022 Jul 14;65(13):9063-9075. doi: 10.1021/acs.jmedchem.2c00313. Epub 2022 Jul 2. J Med Chem. 2022. PMID: 35785990

7

Phosphorylation in the intrinsically disordered region of F-BAR protein Imp2 regulates its contractile ring recruitment.

Willet AH, Igarashi MG, Chen JS, Bhattacharjee R, Ren L, Cullati SN, Elmore ZC, Roberts-Galbraith RH, Johnson AE, Beckley JR, Gould KL. Willet AH, et al. Among authors: beckley jr. J Cell Sci. 2021 Aug 15;134(16):jcs258645. doi: 10.1242/jcs.258645. Epub 2021 Aug 17. J Cell Sci. 2021. PMID: 34402513 Free PMC article.

8

Antinociceptive properties of an isoform-selective inhibitor of Nav1.7 derived from saxitoxin in mouse models of pain.

Beckley JT, Pajouhesh H, Luu G, Klas S, Delwig A, Monteleone D, Zhou X, Giuvelis D, Meng ID, Yeomans DC, Hunter JC, Mulcahy JV. Beckley JT, et al. Pain. 2021 Apr 1;162(4):1250-1261. doi: 10.1097/j.pain.0000000000002112. Pain. 2021. PMID: 33086288 Free PMC article.

9

Discovery of a selective, state-independent inhibitor of Na_V1.7 by modification of guanidinium toxins.

Pajouhesh H, Beckley JT, Delwig A, Hajare HS, Luu G, Monteleone D, Zhou X, Ligutti J, Amagasu S, Moyer BD, Yeomans DC, Du Bois J, Mulcahy JV. Pajouhesh H, et al. Among authors: beckley jt. Sci Rep. 2020 Sep 9;10(1):14791. doi: 10.1038/s41598-020-71135-2. Sci Rep. 2020. PMID: 32908170 Free PMC article.

10

CRISPR-mediated gene targeting of CK1δ/ε leads to enhanced understanding of their role in endocytosis via phosphoregulation of GAPVD1.

Guillen RX, Beckley JR, Chen JS, Gould KL. Guillen RX, et al. Among authors: beckley jr. Sci Rep. 2020 Apr 22;10(1):6797. doi: 10.1038/s41598-020-63669-2. Sci Rep. 2020. PMID: 32321936 Free PMC article.

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