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Regulation of picornavirus gene expression.
Bedard KM, Semler BL. Bedard KM, et al. Microbes Infect. 2004 Jun;6(7):702-13. doi: 10.1016/j.micinf.2004.03.001. Microbes Infect. 2004. PMID: 15158778 Review.
A nucleo-cytoplasmic SR protein functions in viral IRES-mediated translation initiation.
Bedard KM, Daijogo S, Semler BL. Bedard KM, et al. EMBO J. 2007 Jan 24;26(2):459-67. doi: 10.1038/sj.emboj.7601494. Epub 2006 Dec 21. EMBO J. 2007. PMID: 17183366 Free PMC article.
Multimerization of poly(rC) binding protein 2 is required for translation initiation mediated by a viral IRES.
Bedard KM, Walter BL, Semler BL. Bedard KM, et al. RNA. 2004 Aug;10(8):1266-76. doi: 10.1261/rna.7070304. Epub 2004 Jul 9. RNA. 2004. PMID: 15247434 Free PMC article.
Targeting Innate Immunity for Antiviral Therapy through Small Molecule Agonists of the RLR Pathway.
Pattabhi S, Wilkins CR, Dong R, Knoll ML, Posakony J, Kaiser S, Mire CE, Wang ML, Ireton RC, Geisbert TW, Bedard KM, Iadonato SP, Loo YM, Gale M Jr. Pattabhi S, et al. Among authors: bedard km. J Virol. 2015 Dec 16;90(5):2372-87. doi: 10.1128/JVI.02202-15. J Virol. 2015. PMID: 26676770 Free PMC article.
Isoflavone agonists of IRF-3 dependent signaling have antiviral activity against RNA viruses.
Bedard KM, Wang ML, Proll SC, Loo YM, Katze MG, Gale M Jr, Iadonato SP. Bedard KM, et al. J Virol. 2012 Jul;86(13):7334-44. doi: 10.1128/JVI.06867-11. Epub 2012 Apr 24. J Virol. 2012. PMID: 22532686 Free PMC article.
The E6 oncoproteins from human betapapillomaviruses differentially activate telomerase through an E6AP-dependent mechanism and prolong the lifespan of primary keratinocytes.
Bedard KM, Underbrink MP, Howie HL, Galloway DA. Bedard KM, et al. J Virol. 2008 Apr;82(8):3894-902. doi: 10.1128/JVI.01818-07. Epub 2008 Feb 6. J Virol. 2008. PMID: 18256157 Free PMC article.
E6 proteins from multiple human betapapillomavirus types degrade Bak and protect keratinocytes from apoptosis after UVB irradiation.
Underbrink MP, Howie HL, Bedard KM, Koop JI, Galloway DA. Underbrink MP, et al. Among authors: bedard km. J Virol. 2008 Nov;82(21):10408-17. doi: 10.1128/JVI.00902-08. Epub 2008 Aug 20. J Virol. 2008. PMID: 18715924 Free PMC article.
A small-molecule IRF3 agonist functions as an influenza vaccine adjuvant by modulating the antiviral immune response.
Probst P, Grigg JB, Wang M, Muñoz E, Loo YM, Ireton RC, Gale M Jr, Iadonato SP, Bedard KM. Probst P, et al. Among authors: bedard km. Vaccine. 2017 Apr 4;35(15):1964-1971. doi: 10.1016/j.vaccine.2017.01.053. Epub 2017 Mar 6. Vaccine. 2017. PMID: 28279563
A potent Lassa virus antiviral targets an arenavirus virulence determinant.
Madu IG, Files M, Gharaibeh DN, Moore AL, Jung KH, Gowen BB, Dai D, Jones KF, Tyavanagimatt SR, Burgeson JR, Korth MJ, Bedard KM, Iadonato SP, Amberg SM. Madu IG, et al. Among authors: bedard km. PLoS Pathog. 2018 Dec 21;14(12):e1007439. doi: 10.1371/journal.ppat.1007439. eCollection 2018 Dec. PLoS Pathog. 2018. PMID: 30576397 Free PMC article.
Preliminary evaluation of effect of two visual aid devices on navigation in blind dogs.
Bedard KM, Myrna KE, Diehl KA. Bedard KM, et al. J Small Anim Pract. 2020 May;61(5):308-315. doi: 10.1111/jsap.13120. Epub 2020 Feb 20. J Small Anim Pract. 2020. PMID: 32077502
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