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A multiplatform strategy for the discovery of conventional monoclonal antibodies that inhibit the voltage-gated potassium channel Kv1.3.
Bednenko J, Harriman R, Mariën L, Nguyen HM, Agrawal A, Papoyan A, Bisharyan Y, Cardarelli J, Cassidy-Hanley D, Clark T, Pedersen D, Abdiche Y, Harriman W, van der Woning B, de Haard H, Collarini E, Wulff H, Colussi P. Bednenko J, et al. MAbs. 2018 May/Jun;10(4):636-650. doi: 10.1080/19420862.2018.1445451. Epub 2018 Apr 2. MAbs. 2018. PMID: 29494279 Free PMC article.
Membrane protein production and formulation for drug discovery.
Gulezian E, Crivello C, Bednenko J, Zafra C, Zhang Y, Colussi P, Hussain S. Gulezian E, et al. Among authors: bednenko j. Trends Pharmacol Sci. 2021 Aug;42(8):657-674. doi: 10.1016/j.tips.2021.05.006. Trends Pharmacol Sci. 2021. PMID: 34270922 Review.
Modulation of Lymphocyte Potassium Channel KV1.3 by Membrane-Penetrating, Joint-Targeting Immunomodulatory Plant Defensin.
Ong ST, Bajaj S, Tanner MR, Chang SC, Krishnarjuna B, Ng XR, Morales RAV, Chen MW, Luo D, Patel D, Yasmin S, Ng JJH, Zhuang Z, Nguyen HM, El Sahili A, Lescar J, Patil R, Charman SA, Robins EG, Goggi JL, Tan PW, Sadasivam P, Ramasamy B, Hartimath SV, Dhawan V, Bednenko J, Colussi P, Wulff H, Pennington MW, Kuyucak S, Norton RS, Beeton C, Chandy KG. Ong ST, et al. Among authors: bednenko j. ACS Pharmacol Transl Sci. 2020 May 14;3(4):720-736. doi: 10.1021/acsptsci.0c00035. eCollection 2020 Aug 14. ACS Pharmacol Transl Sci. 2020. PMID: 32832873 Free PMC article.
Cross-talk between snurportin1 subdomains.
Ospina JK, Gonsalvez GB, Bednenko J, Darzynkiewicz E, Gerace L, Matera AG. Ospina JK, et al. Among authors: bednenko j. Mol Biol Cell. 2005 Oct;16(10):4660-71. doi: 10.1091/mbc.e05-04-0316. Epub 2005 Jul 19. Mol Biol Cell. 2005. PMID: 16030253 Free PMC article.
17 results