Begley TJ - Search Results

1

Increased tRNA modification and gene-specific codon usage regulate cell cycle progression during the DNA damage response.

Patil A, Dyavaiah M, Joseph F, Rooney JP, Chan CT, Dedon PC, Begley TJ. Patil A, et al. Among authors: begley tj. Cell Cycle. 2012 Oct 1;11(19):3656-65. doi: 10.4161/cc.21919. Epub 2012 Aug 30. Cell Cycle. 2012. PMID: 22935709 Free PMC article.

2

The DNA-damage signature in Saccharomyces cerevisiae is associated with single-strand breaks in DNA.

Fry RC, DeMott MS, Cosgrove JP, Begley TJ, Samson LD, Dedon PC. Fry RC, et al. Among authors: begley tj. BMC Genomics. 2006 Dec 12;7:313. doi: 10.1186/1471-2164-7-313. BMC Genomics. 2006. PMID: 17163986 Free PMC article.

3

Trm9-catalyzed tRNA modifications link translation to the DNA damage response.

Begley U, Dyavaiah M, Patil A, Rooney JP, DiRenzo D, Young CM, Conklin DS, Zitomer RS, Begley TJ. Begley U, et al. Among authors: begley tj. Mol Cell. 2007 Dec 14;28(5):860-70. doi: 10.1016/j.molcel.2007.09.021. Mol Cell. 2007. PMID: 18082610 Free PMC article.

4

A molecular bar-coded DNA repair resource for pooled toxicogenomic screens.

Rooney JP, Patil A, Zappala MR, Conklin DS, Cunningham RP, Begley TJ. Rooney JP, et al. Among authors: begley tj. DNA Repair (Amst). 2008 Nov 1;7(11):1855-68. doi: 10.1016/j.dnarep.2008.07.013. Epub 2008 Sep 10. DNA Repair (Amst). 2008. PMID: 18723126 Free PMC article.

5

Systems based mapping demonstrates that recovery from alkylation damage requires DNA repair, RNA processing, and translation associated networks.

Rooney JP, George AD, Patil A, Begley U, Bessette E, Zappala MR, Huang X, Conklin DS, Cunningham RP, Begley TJ. Rooney JP, et al. Among authors: begley tj, begley u. Genomics. 2009 Jan;93(1):42-51. doi: 10.1016/j.ygeno.2008.09.001. Epub 2008 Oct 16. Genomics. 2009. PMID: 18824089 Free PMC article.

6

A genome-wide screen in Saccharomyces cerevisiae reveals pathways affected by arsenic toxicity.

Zhou X, Arita A, Ellen TP, Liu X, Bai J, Rooney JP, Kurtz AD, Klein CB, Dai W, Begley TJ, Costa M. Zhou X, et al. Among authors: begley tj. Genomics. 2009 Nov;94(5):294-307. doi: 10.1016/j.ygeno.2009.07.003. Epub 2009 Jul 22. Genomics. 2009. PMID: 19631266 Free PMC article.

7

A genome-wide deletion mutant screen identifies pathways affected by nickel sulfate in Saccharomyces cerevisiae.

Arita A, Zhou X, Ellen TP, Liu X, Bai J, Rooney JP, Kurtz A, Klein CB, Dai W, Begley TJ, Costa M. Arita A, et al. Among authors: begley tj. BMC Genomics. 2009 Nov 15;10:524. doi: 10.1186/1471-2164-10-524. BMC Genomics. 2009. PMID: 19917080 Free PMC article.

8

Human AlkB homolog ABH8 Is a tRNA methyltransferase required for wobble uridine modification and DNA damage survival.

Fu D, Brophy JA, Chan CT, Atmore KA, Begley U, Paules RS, Dedon PC, Begley TJ, Samson LD. Fu D, et al. Among authors: begley tj, begley u. Mol Cell Biol. 2010 May;30(10):2449-59. doi: 10.1128/MCB.01604-09. Epub 2010 Mar 22. Mol Cell Biol. 2010. PMID: 20308323 Free PMC article.

9

A quantitative systems approach reveals dynamic control of tRNA modifications during cellular stress.

Chan CT, Dyavaiah M, DeMott MS, Taghizadeh K, Dedon PC, Begley TJ. Chan CT, et al. Among authors: begley tj. PLoS Genet. 2010 Dec 16;6(12):e1001247. doi: 10.1371/journal.pgen.1001247. PLoS Genet. 2010. PMID: 21187895 Free PMC article.

10

Cross-species Functionome analysis identifies proteins associated with DNA repair, translation and aerobic respiration as conserved modulators of UV-toxicity.

Rooney JP, Patil A, Joseph F, Endres L, Begley U, Zappala MR, Cunningham RP, Begley TJ. Rooney JP, et al. Among authors: begley tj, begley u. Genomics. 2011 Mar;97(3):133-47. doi: 10.1016/j.ygeno.2010.12.005. Epub 2010 Dec 30. Genomics. 2011. PMID: 21195161 Free PMC article.

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