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Identification of a Synthetic Lethal Relationship between Nucleotide Excision Repair Deficiency and Irofulven Sensitivity in Urothelial Cancer.
Börcsök J, Sztupinszki Z, Bekele R, Gao SP, Diossy M, Samant AS, Dillon KM, Tisza V, Spisák S, Rusz O, Csabai I, Pappot H, Frazier ZJ, Konieczkowski DJ, Liu D, Vasani N, Rodrigues JA, Solit DB, Hoffman-Censits JH, Plimack ER, Rosenberg JE, Lazaro JB, Taplin ME, Iyer G, Brunak S, Lozsa R, Van Allen EM, Szüts D, Mouw KW, Szallasi Z. Börcsök J, et al. Among authors: bekele r. Clin Cancer Res. 2021 Apr 1;27(7):2011-2022. doi: 10.1158/1078-0432.CCR-20-3316. Epub 2020 Nov 18. Clin Cancer Res. 2021. PMID: 33208343 Free PMC article.
How can molecular abnormalities influence our clinical approach.
Wei W, Giulia F, Luffer S, Kumar R, Wu B, Tavallai M, Bekele RT, Birrer MJ. Wei W, et al. Among authors: bekele rt. Ann Oncol. 2017 Nov 1;28(suppl_8):viii16-viii24. doi: 10.1093/annonc/mdx447. Ann Oncol. 2017. PMID: 29232470 Free article. Review.
Activity of Enfortumab Vedotin and Sacituzumab Govitecan with Radiation in Preclinical Models of Bladder Cancer.
Zhou Y, D'Andrea VD, Shanmugam SP, Stelter I, Stormoen DR, Chroneos R, Hanlon T, Epstein I, Bekele RT, Anderson WJ, Carvalho FFL, Bellmunt J, Mouw KW. Zhou Y, et al. Among authors: bekele rt. Eur Urol. 2024 Mar 23:S0302-2838(24)02231-0. doi: 10.1016/j.eururo.2024.03.013. Online ahead of print. Eur Urol. 2024. PMID: 38523005 No abstract available.
ATM deficiency confers specific therapeutic vulnerabilities in bladder cancer.
Zhou Y, Börcsök J, Adib E, Kamran SC, Neil AJ, Stawiski K, Freeman D, Stormoen DR, Sztupinszki Z, Samant A, Nassar A, Bekele RT, Hanlon T, Valentine H, Epstein I, Sharma B, Felt K, Abbosh P, Wu CL, Efstathiou JA, Miyamoto DT, Anderson W, Szallasi Z, Mouw KW. Zhou Y, et al. Among authors: bekele rt. Sci Adv. 2023 Nov 24;9(47):eadg2263. doi: 10.1126/sciadv.adg2263. Epub 2023 Nov 22. Sci Adv. 2023. PMID: 37992168 Free PMC article.
16 results