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A placebo-controlled trial of pioglitazone in subjects with nonalcoholic steatohepatitis.
Belfort R, Harrison SA, Brown K, Darland C, Finch J, Hardies J, Balas B, Gastaldelli A, Tio F, Pulcini J, Berria R, Ma JZ, Dwivedi S, Havranek R, Fincke C, DeFronzo R, Bannayan GA, Schenker S, Cusi K. Belfort R, et al. N Engl J Med. 2006 Nov 30;355(22):2297-307. doi: 10.1056/NEJMoa060326. N Engl J Med. 2006. PMID: 17135584 Clinical Trial.
Reduction in hematocrit level after pioglitazone treatment is correlated with decreased plasma free testosterone level, not hemodilution, in women with polycystic ovary syndrome.
Berria R, Gastaldelli A, Lucidi S, Belfort R, De Filippis E, Easton C, Brytzki R, Cusi K, Jovanovic L, DeFronzo R. Berria R, et al. Clin Pharmacol Ther. 2006 Aug;80(2):105-14. doi: 10.1016/j.clpt.2006.03.014. Epub 2006 Jun 30. Clin Pharmacol Ther. 2006. PMID: 16890572
Increased collagen content in insulin-resistant skeletal muscle.
Berria R, Wang L, Richardson DK, Finlayson J, Belfort R, Pratipanawatr T, De Filippis EA, Kashyap S, Mandarino LJ. Berria R, et al. Am J Physiol Endocrinol Metab. 2006 Mar;290(3):E560-5. doi: 10.1152/ajpendo.00202.2005. Epub 2005 Oct 25. Am J Physiol Endocrinol Metab. 2006. PMID: 16249255
Insulin resistance is associated with impaired nitric oxide synthase activity in skeletal muscle of type 2 diabetic subjects.
Kashyap SR, Roman LJ, Lamont J, Masters BS, Bajaj M, Suraamornkul S, Belfort R, Berria R, Kellogg DL Jr, Liu Y, DeFronzo RA. Kashyap SR, et al. J Clin Endocrinol Metab. 2005 Feb;90(2):1100-5. doi: 10.1210/jc.2004-0745. Epub 2004 Nov 23. J Clin Endocrinol Metab. 2005. PMID: 15562034
Discordant effects of a chronic physiological increase in plasma FFA on insulin signaling in healthy subjects with or without a family history of type 2 diabetes.
Kashyap SR, Belfort R, Berria R, Suraamornkul S, Pratipranawatr T, Finlayson J, Barrentine A, Bajaj M, Mandarino L, DeFronzo R, Cusi K. Kashyap SR, et al. Am J Physiol Endocrinol Metab. 2004 Sep;287(3):E537-46. doi: 10.1152/ajpendo.00541.2003. Epub 2004 May 4. Am J Physiol Endocrinol Metab. 2004. PMID: 15126243
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