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Year Number of Results
2008 1
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80 results

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Page 1
MYC multimers shield stalled replication forks from RNA polymerase.
Solvie D, Baluapuri A, Uhl L, Fleischhauer D, Endres T, Papadopoulos D, Aziba A, Gaballa A, Mikicic I, Isaakova E, Giansanti C, Jansen J, Jungblut M, Klein T, Schülein-Völk C, Maric H, Doose S, Sauer M, Beli P, Rosenwald A, Dobbelstein M, Wolf E, Eilers M. Solvie D, et al. Among authors: beli p. Nature. 2022 Dec;612(7938):148-155. doi: 10.1038/s41586-022-05469-4. Epub 2022 Nov 23. Nature. 2022. PMID: 36424410
DNA-protein cross-links promote cGAS-STING-driven premature aging and embryonic lethality.
Tomaskovic I, Prieto-Garcia C, Boskovic M, Glumac M, Tsai TL, Mosler T, Kazi R, Rathore R, Andrade J, Hoffmann M, Giuliani G, Jacomin AC, Pereira RS, Knop E, Wachsmuth L, Beli P, Husnjak K, Pasparakis M, Ablasser A, Krause DS, Potente M, Papathanasiou S, Terzic J, Dikic I. Tomaskovic I, et al. Among authors: beli p. Science. 2026 Jan 29;391(6784):eadx9445. doi: 10.1126/science.adx9445. Epub 2026 Jan 29. Science. 2026. PMID: 41610251
Pathogenic proteotoxicity of cryptic splicing is alleviated by ubiquitination and ER-phagy.
Prieto-Garcia C, Matkovic V, Mosler T, Li C, Liang J, Oo JA, Haidle F, Mačinković I, Cabrera-Orefice A, Berkane R, Giuliani G, Xu F, Jacomin AC, Tomaskovic I, Basoglu M, Hoffmann ME, Rathore R, Cetin R, Boutguetait D, Bozkurt S, Hernández Cañás MC, Keller M, Busam J, Shah VJ, Wittig I, Kaulich M, Beli P, Galej WP, Ebersberger I, Wang L, Münch C, Stolz A, Brandes RP, Tse WKF, Eimer S, Stainier DYR, Legewie S, Zarnack K, Müller-McNicoll M, Dikic I. Prieto-Garcia C, et al. Among authors: beli p. Science. 2024 Nov 15;386(6723):768-776. doi: 10.1126/science.adi5295. Epub 2024 Nov 14. Science. 2024. PMID: 39541449
The MYCN oncoprotein is an RNA-binding accessory factor of the nuclear exosome targeting complex.
Papadopoulos D, Ha SA, Fleischhauer D, Uhl L, Russell TJ, Mikicic I, Schneider K, Brem A, Valanju OR, Cossa G, Gallant P, Schuelein-Voelk C, Maric HM, Beli P, Büchel G, Vos SM, Eilers M. Papadopoulos D, et al. Among authors: beli p. Mol Cell. 2024 Jun 6;84(11):2070-2086.e20. doi: 10.1016/j.molcel.2024.04.007. Epub 2024 May 3. Mol Cell. 2024. PMID: 38703770 Free article.
K6-linked ubiquitylation marks formaldehyde-induced RNA-protein crosslinks for resolution.
Suryo Rahmanto A, Blum CJ, Scalera C, Heidelberger JB, Mesitov M, Horn-Ghetko D, Gräf JF, Mikicic I, Hobrecht R, Orekhova A, Ostermaier M, Ebersberger S, Möckel MM, Krapoth N, Da Silva Fernandes N, Mizi A, Zhu Y, Chen JX, Choudhary C, Papantonis A, Ulrich HD, Schulman BA, König J, Beli P. Suryo Rahmanto A, et al. Among authors: beli p. Mol Cell. 2023 Dec 7;83(23):4272-4289.e10. doi: 10.1016/j.molcel.2023.10.011. Epub 2023 Nov 10. Mol Cell. 2023. PMID: 37951215 Free article.
Allosteric activation of the SPRTN protease by ubiquitin maintains genome stability.
Dürauer S, Kang HS, Wiebeler C, Machida Y, Schnapka DS, Yaneva D, Renz C, Götz MJ, Weickert P, Major AC, Rahmanto AS, Gutenthaler-Tietze SM, Daumann LJ, Beli P, Ulrich HD, Sattler M, Machida YJ, Schwierz N, Stingele J. Dürauer S, et al. Among authors: beli p. Nat Commun. 2025 Jul 21;16(1):5422. doi: 10.1038/s41467-025-61224-z. Nat Commun. 2025. PMID: 40691134 Free PMC article.
The USP11/TCEAL1 complex promotes transcription elongation to sustain oncogenic gene expression in neuroblastoma.
Dehmer M, Trunk K, Gallant P, Fleischhauer D, Müller M, Herold S, Cossa G, Conte F, Koster J, Sauer F, Schülein-Völk C, Ade CP, Vidal R, Kisker C, Versteeg R, Beli P, Vos SM, Eilers M, Büchel G. Dehmer M, et al. Among authors: beli p. Genes Dev. 2025 Jun 2;39(11-12):751-769. doi: 10.1101/gad.352166.124. Genes Dev. 2025. PMID: 40250979 Free PMC article.
Combined inhibition of Aurora-A and ATR kinase results in regression of MYCN-amplified neuroblastoma.
Roeschert I, Poon E, Henssen AG, Garcia HD, Gatti M, Giansanti C, Jamin Y, Ade CP, Gallant P, Schülein-Völk C, Beli P, Richards M, Rosenfeldt M, Altmeyer M, Anderson J, Eggert A, Dobbelstein M, Bayliss R, Chesler L, Büchel G, Eilers M. Roeschert I, et al. Among authors: beli p. Nat Cancer. 2021 Mar;2(3):312-326. doi: 10.1038/s43018-020-00171-8. Epub 2021 Feb 11. Nat Cancer. 2021. PMID: 33768209 Free PMC article.
When RNA damage induces DNA breaks.
Mikicic I, Beli P. Mikicic I, et al. Among authors: beli p. Trends Cell Biol. 2025 May;35(5):359-360. doi: 10.1016/j.tcb.2025.03.004. Epub 2025 Apr 9. Trends Cell Biol. 2025. PMID: 40210534
80 results