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Association of rapamycin treatment with the modulation of purine metabolism, reduced microglial inflammatory responses, improved mitochondrial energy metabolism, and alleviation of fatigue symptoms in ME/CFS subjects: pilot findings from phase-II observational study.
Gile B, Bulbule S, Toriola MA, Ruan BT, Marium S, Benko A, Grach S, Mueller M, Bateman L, Bell J, Yellman B, Berner J, Chheda B, Kaufman D, Gottschalk G, Roy A. Gile B, et al. J Transl Med. 2026 Jul 10;24(1):921. doi: 10.1186/s12967-026-08575-3. J Transl Med. 2026. PMID: 42432754 Free PMC article. Clinical Trial.
Low Dose Rapamycin Alleviates Clinical Symptoms of Fatigue and PEM in ME/CFS Patients via Improvement of Autophagy.
Ruan BT, Bulbule S, Reyes A, Chheda B, Bateman L, Bell J, Yellman B, Grach S, Berner J, Peterson DL, Kaufman D, Roy A, Gottschalk CG. Ruan BT, et al. Res Sq [Preprint]. 2025 Jun 3:rs.3.rs-6596158. doi: 10.21203/rs.3.rs-6596158/v1. Res Sq. 2025. Update in: J Transl Med. 2025 Oct 21;23(1):1148. doi: 10.1186/s12967-025-07213-8. PMID: 40502741 Free PMC article. Updated. Preprint.
Chemoproteomic discovery of a brain-penetrant, covalent NLRP3 inhibitor that binds a novel allosteric pocket.
Rogness DC, Sievert EP, Vartabedian VF, Bernard SM, Aitchison E, Tao W, Lindvall M, Qian J, Eissler CL, Nordin BE, Horning BD, Kingston C, Lamb KN, Bell JC, Lu B, Pollock J, Shi J, Khattri R, Weinstein DS, Patricelli MP, Cook BN, Simon GM. Rogness DC, et al. Among authors: bell jc. Br J Pharmacol. 2026 Aug 8. doi: 10.1111/bph.70626. Online ahead of print. Br J Pharmacol. 2026. PMID: 42569816
Secondary prevention of myocardial infarction in people with dementia: a multi-jurisdictional retrospective cohort study in Asia, Europe and the USA.
Ilomäki J, Tan GSQ, Qin XS, Tolppanen AM, Lin J, Ma TT, Hsing-Chun Hsieh M, Kim SJ, Marquina C, Lai EC, Wei L, Wood SJ, Wong ICK, Fang G, Hartikainen S, Annis I, Lau KK, Bell JS. Ilomäki J, et al. Among authors: bell js. Age Ageing. 2026 Aug 3;55(8):afag220. doi: 10.1093/ageing/afag220. Age Ageing. 2026. PMID: 42566699 Free PMC article.
6,684 results