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CRISPR/Cas9-mediated inactivation of the phosphatase activity of soluble epoxide hydrolase prevents obesity and cardiac ischemic injury.
Leuillier M, Duflot T, Ménoret S, Messaoudi H, Djerada Z, Groussard D, Denis RGP, Chevalier L, Karoui A, Panthu B, Thiébaut PA, Schmitz-Afonso I, Nobis S, Campart C, Henry T, Sautreuil C, Luquet SH, Beseme O, Féliu C, Peyret H, Nicol L, Henry JP, Renet S, Mulder P, Wan D, Tesson L, Heslan JM, Duché A, Jacques S, Ziegler F, Brunel V, Rautureau GJP, Monteil C, do Rego JL, do Rego JC, Afonso C, Hammock B, Madec AM, Pinet F, Richard V, Anegon I, Guignabert C, Morisseau C, Bellien J. Leuillier M, et al. Among authors: bellien j. J Adv Res. 2023 Jan;43:163-174. doi: 10.1016/j.jare.2022.03.004. Epub 2022 Mar 12. J Adv Res. 2023. PMID: 36585106 Free PMC article.
Preservation of epoxyeicosatrienoic acid bioavailability prevents renal allograft dysfunction and cardiovascular alterations in kidney transplant recipients.
Duflot T, Laurent C, Soudey A, Fonrose X, Hamzaoui M, Iacob M, Bertrand D, Favre J, Etienne I, Roche C, Coquerel D, Le Besnerais M, Louhichi S, Tarlet T, Li D, Brunel V, Morisseau C, Richard V, Joannidès R, Stanke-Labesque F, Lamoureux F, Guerrot D, Bellien J. Duflot T, et al. Among authors: bellien j. Sci Rep. 2021 Feb 12;11(1):3739. doi: 10.1038/s41598-021-83274-1. Sci Rep. 2021. PMID: 33580125 Free PMC article.
Diabetic CVD--soluble epoxide hydrolase as a target.
Lorthioir A, Guerrot D, Joannides R, Bellien J. Lorthioir A, et al. Among authors: bellien j. Cardiovasc Hematol Agents Med Chem. 2012 Sep;10(3):212-22. doi: 10.2174/187152512802651042. Cardiovasc Hematol Agents Med Chem. 2012. PMID: 22632263 Review.
84 results