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Site-specific acetylation mark on an essential chromatin-remodeling complex promotes resistance to replication stress.
Charles GM, Chen C, Shih SC, Collins SR, Beltrao P, Zhang X, Sharma T, Tan S, Burlingame AL, Krogan NJ, Madhani HD, Narlikar GJ. Charles GM, et al. Among authors: beltrao p. Proc Natl Acad Sci U S A. 2011 Jun 28;108(26):10620-5. doi: 10.1073/pnas.1019735108. Epub 2011 Jun 14. Proc Natl Acad Sci U S A. 2011. PMID: 21673141 Free PMC article.
The effects of pathogenic and likely pathogenic variants for inherited hemostasis disorders in 140 214 UK Biobank participants.
Stefanucci L, Collins J, Sims MC, Barrio-Hernandez I, Sun L, Burren OS, Perfetto L, Bender I, Callahan TJ, Fleming K, Guerrero JA, Hermjakob H, Martin MJ, Stephenson J, Paneerselvam K, Petrovski S, Porras P, Robinson PN, Wang Q, Watkins X, Frontini M, Laskowski RA, Beltrao P, Di Angelantonio E, Gomez K, Laffan M, Ouwehand WH, Mumford AD, Freson K, Carss K, Downes K, Gleadall N, Megy K, Bruford E, Vuckovic D. Stefanucci L, et al. Among authors: beltrao p. Blood. 2023 Dec 14;142(24):2055-2068. doi: 10.1182/blood.2023020118. Blood. 2023. PMID: 37647632 Free PMC article.
Clustering predicted structures at the scale of the known protein universe.
Barrio-Hernandez I, Yeo J, Jänes J, Mirdita M, Gilchrist CLM, Wein T, Varadi M, Velankar S, Beltrao P, Steinegger M. Barrio-Hernandez I, et al. Among authors: beltrao p. Nature. 2023 Oct;622(7983):637-645. doi: 10.1038/s41586-023-06510-w. Epub 2023 Sep 13. Nature. 2023. PMID: 37704730 Free PMC article.
Network expansion of genetic associations defines a pleiotropy map of human cell biology.
Barrio-Hernandez I, Schwartzentruber J, Shrivastava A, Del-Toro N, Gonzalez A, Zhang Q, Mountjoy E, Suveges D, Ochoa D, Ghoussaini M, Bradley G, Hermjakob H, Orchard S, Dunham I, Anderson CA, Porras P, Beltrao P. Barrio-Hernandez I, et al. Among authors: beltrao p. Nat Genet. 2023 Mar;55(3):389-398. doi: 10.1038/s41588-023-01327-9. Epub 2023 Feb 23. Nat Genet. 2023. PMID: 36823319 Free PMC article.
Towards a structurally resolved human protein interaction network.
Burke DF, Bryant P, Barrio-Hernandez I, Memon D, Pozzati G, Shenoy A, Zhu W, Dunham AS, Albanese P, Keller A, Scheltema RA, Bruce JE, Leitner A, Kundrotas P, Beltrao P, Elofsson A. Burke DF, et al. Among authors: beltrao p. Nat Struct Mol Biol. 2023 Feb;30(2):216-225. doi: 10.1038/s41594-022-00910-8. Epub 2023 Jan 23. Nat Struct Mol Biol. 2023. PMID: 36690744 Free PMC article.
102 results