Ben-Sahra I - Search Results

Year	Number of Results
2008	2
2009	2
2010	4
2011	1
2012	3
2013	4
2014	3
2015	1
2016	3
2017	5
2018	4
2019	5
2020	3
2021	4

1

De novo purine biosynthesis is a major driver of chemoresistance in glioblastoma.

Shireman JM, Atashi F, Lee G, Ali ES, Saathoff MR, Park CH, Savchuk S, Baisiwala S, Miska J, Lesniak MS, James CD, Stupp R, Kumthekar P, Horbinski CM, Ben-Sahra I, Ahmed AU. Shireman JM, et al. Among authors: ben sahra i. Brain. 2021 May 7;144(4):1230-1246. doi: 10.1093/brain/awab020. Brain. 2021. PMID: 33855339

2

mTORC1 stimulates cell growth through SAM synthesis and m⁶A mRNA-dependent control of protein synthesis.

Villa E, Sahu U, O'Hara BP, Ali ES, Helmin KA, Asara JM, Gao P, Singer BD, Ben-Sahra I. Villa E, et al. Among authors: ben sahra i. Mol Cell. 2021 Mar 17:S1097-2765(21)00177-5. doi: 10.1016/j.molcel.2021.03.009. Online ahead of print. Mol Cell. 2021. PMID: 33756106

3

NOTCH1-driven UBR7 stimulates nucleotide biosynthesis to promote T cell acute lymphoblastic leukemia.

Srivastava S, Sahu U, Zhou Y, Hogan AK, Sathyan KM, Bodner J, Huang J, Wong KA, Khalatyan N, Savas JN, Ntziachristos P, Ben-Sahra I, Foltz DR. Srivastava S, et al. Among authors: ben sahra i. Sci Adv. 2021 Jan 27;7(5):eabc9781. doi: 10.1126/sciadv.abc9781. Print 2021 Jan. Sci Adv. 2021. PMID: 33571115 Free PMC article.

4

Author Correction: Senescent cells promote tissue NAD⁺ decline during ageing via the activation of CD38⁺ macrophages.

Covarrubias AJ, Kale A, Perrone R, Lopez-Dominguez JA, Pisco AO, Kasler HG, Schmidt MS, Heckenbach I, Kwok R, Wiley CD, Wong HS, Gibbs E, Iyer SS, Basisty N, Wu Q, Kim IJ, Silva E, Vitangcol K, Shin KO, Lee YM, Riley R, Ben-Sahra I, Ott M, Schilling B, Scheibye-Knudsen M, Ishihara K, Quake SR, Newman J, Brenner C, Campisi J, Verdin E. Covarrubias AJ, et al. Among authors: ben sahra i. Nat Metab. 2021 Jan;3(1):120-121. doi: 10.1038/s42255-020-00328-w. Nat Metab. 2021. PMID: 33303985 No abstract available.

5

Senescent cells promote tissue NAD⁺ decline during ageing via the activation of CD38⁺ macrophages.

Covarrubias AJ, Kale A, Perrone R, Lopez-Dominguez JA, Pisco AO, Kasler HG, Schmidt MS, Heckenbach I, Kwok R, Wiley CD, Wong HS, Gibbs E, Iyer SS, Basisty N, Wu Q, Kim IJ, Silva E, Vitangcol K, Shin KO, Lee YM, Riley R, Ben-Sahra I, Ott M, Schilling B, Scheibye-Knudsen M, Ishihara K, Quake SR, Newman J, Brenner C, Campisi J, Verdin E. Covarrubias AJ, et al. Among authors: ben sahra i. Nat Metab. 2020 Nov;2(11):1265-1283. doi: 10.1038/s42255-020-00305-3. Epub 2020 Nov 16. Nat Metab. 2020. PMID: 33199924 Free PMC article.

6

A spoonful of DHAP keeps mTORC1 running on sugars.

Hoxhaj G, Locasale JW, Ben-Sahra I. Hoxhaj G, et al. Among authors: ben sahra i. Nat Metab. 2020 Sep;2(9):801-802. doi: 10.1038/s42255-020-0246-1. Nat Metab. 2020. PMID: 32719540 No abstract available.

7

ERK2 Phosphorylates PFAS to Mediate Posttranslational Control of De Novo Purine Synthesis.

Ali ES, Sahu U, Villa E, O'Hara BP, Gao P, Beaudet C, Wood AW, Asara JM, Ben-Sahra I. Ali ES, et al. Among authors: ben sahra i. Mol Cell. 2020 Jun 18;78(6):1178-1191.e6. doi: 10.1016/j.molcel.2020.05.001. Epub 2020 Jun 1. Mol Cell. 2020. PMID: 32485148

8

Cancer Cells Tune the Signaling Pathways to Empower de Novo Synthesis of Nucleotides.

Villa E, Ali ES, Sahu U, Ben-Sahra I. Villa E, et al. Among authors: ben sahra i. Cancers (Basel). 2019 May 17;11(5):688. doi: 10.3390/cancers11050688. Cancers (Basel). 2019. PMID: 31108873 Free PMC article. Review.

9

PGC1α Inhibits Polyamine Synthesis to Suppress Prostate Cancer Aggressiveness.

Kaminski L, Torrino S, Dufies M, Djabari Z, Haider R, Roustan FR, Jaune E, Laurent K, Nottet N, Michiels JF, Gesson M, Rocchi S, Mazure NM, Durand M, Tanti JF, Ambrosetti D, Clavel S, Ben-Sahra I, Bost F. Kaminski L, et al. Among authors: ben sahra i. Cancer Res. 2019 Jul 1;79(13):3268-3280. doi: 10.1158/0008-5472.CAN-18-2043. Epub 2019 May 7. Cancer Res. 2019. PMID: 31064849 Free PMC article.

10

Direct stimulation of NADP⁺ synthesis through Akt-mediated phosphorylation of NAD kinase.

Hoxhaj G, Ben-Sahra I, Lockwood SE, Timson RC, Byles V, Henning GT, Gao P, Selfors LM, Asara JM, Manning BD. Hoxhaj G, et al. Among authors: ben sahra i. Science. 2019 Mar 8;363(6431):1088-1092. doi: 10.1126/science.aau3903. Science. 2019. PMID: 30846598 Free PMC article.

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