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Benadrostin, new inhibitor of poly(ADP-ribose) synthetase, produced by actinomycetes. II. Structure determination.
Yoshida S, Naganawa H, Aoyagi T, Takeuchi T, Umezawa H. Yoshida S, et al. J Antibiot (Tokyo). 1988 Aug;41(8):1015-8. doi: 10.7164/antibiotics.41.1015. J Antibiot (Tokyo). 1988. PMID: 3139602 Free article.
Benadrostin, a new inhibitor of poly(ADP-ribose) synthetase, has been isolated from the culture broth of Streptomyces flavovirens MH499-O'F1. The structure of benadrostin was defined as 8-hydroxy-2H-1,3-benzoxazine-2,4-dione by an analysis of spectral properties and
Benadrostin, a new inhibitor of poly(ADP-ribose) synthetase, has been isolated from the culture broth of Streptomyces flavovirens MH4
Benadrostin, new inhibitor of poly(ADP-ribose) synthetase, produced by actinomycetes. I. Taxonomy, production, isolation, physico-chemical properties and biological activities.
Aoyagi T, Yoshida S, Harada S, Okuyama A, Nakayama C, Yoshida T, Hamada M, Takeuchi T, Umezawa H. Aoyagi T, et al. J Antibiot (Tokyo). 1988 Aug;41(8):1009-14. doi: 10.7164/antibiotics.41.1009. J Antibiot (Tokyo). 1988. PMID: 3139601 Free article.
Benadrostin, a new inhibitor of poly(ADP-ribose) synthetase was discovered in the fermentation broth of Streptomyces flavovirens MH499-O'F1. It was purified by chromatography followed by solvent extraction and then isolated as colorless prisms. Benadrostin has the m
Benadrostin, a new inhibitor of poly(ADP-ribose) synthetase was discovered in the fermentation broth of Streptomyces flavovirens MH49
Discovery of Streptomyces marinisediminis sp. nov., a new thiolutin producing actinomycete isolated from Thai marine sediment.
Pansomsuay R, Fukasem P, Pittayakhajonwut P, Intaraudom C, Suriyachadkun C, Yasawong M, He YW, Tanasupawat S, Qian Y, Thawai C. Pansomsuay R, et al. Sci Rep. 2025 Aug 11;15(1):29301. doi: 10.1038/s41598-025-15081-x. Sci Rep. 2025. PMID: 40790075 Free PMC article.
The crude extract obtained from the culture broth of strain JHD1(T) exhibited strong antimicrobial activity against Gram-positive bacteria and led to the discovery of two promising secondary metabolites, thiolutin and 2,2-dioxidothiolutin, along with 8-amino-2H-benz[e][1,3]oxazin …
The crude extract obtained from the culture broth of strain JHD1(T) exhibited strong antimicrobial activity against Gram-positive bacteria a …
New potent DPPH radical scavengers from a marine-derived actinomycete strain USF-TC31.
Sugiyama Y, Hirota A. Sugiyama Y, et al. Biosci Biotechnol Biochem. 2009 Dec;73(12):2731-4. doi: 10.1271/bbb.90636. Epub 2009 Dec 7. Biosci Biotechnol Biochem. 2009. PMID: 19966460 Free article.
The structures of two novel compounds were determined to be those of N-carbamoyl-2,3-dihydroxybenzamide (5) and 2-acetamido-3-(2,3-dihydroxybenzoylthio)propanoic acid (6), and four known compounds were identified to be anthranilic acid (1), 2,3-dihydroxybenzoic acid (2), 2,3-dihy …
The structures of two novel compounds were determined to be those of N-carbamoyl-2,3-dihydroxybenzamide (5) and 2-acetamido-3-(2,3-dihydroxy …