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Role of Pirh2 in mediating the regulation of p53 and c-Myc.
Hakem A, Bohgaki M, Lemmers B, Tai E, Salmena L, Matysiak-Zablocki E, Jung YS, Karaskova J, Kaustov L, Duan S, Madore J, Boutros P, Sheng Y, Chesi M, Bergsagel PL, Perez-Ordonez B, Mes-Masson AM, Penn L, Squire J, Chen X, Jurisica I, Arrowsmith C, Sanchez O, Benchimol S, Hakem R. Hakem A, et al. Among authors: benchimol s. PLoS Genet. 2011 Nov;7(11):e1002360. doi: 10.1371/journal.pgen.1002360. Epub 2011 Nov 17. PLoS Genet. 2011. PMID: 22125490 Free PMC article.
Cdk9 phosphorylates Pirh2 protein and prevents degradation of p53 protein.
Bagashev A, Fan S, Mukerjee R, Claudio PP, Chabrashvili T, Leng RP, Benchimol S, Sawaya BE. Bagashev A, et al. Among authors: benchimol s. Cell Cycle. 2013 May 15;12(10):1569-77. doi: 10.4161/cc.24733. Epub 2013 Apr 19. Cell Cycle. 2013. PMID: 23603988 Free PMC article.
118 results