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Benchmarking cryo-EM Single Particle Analysis Workflow.
Kim LY, Rice WJ, Eng ET, Kopylov M, Cheng A, Raczkowski AM, Jordan KD, Bobe D, Potter CS, Carragher B. Kim LY, et al. Front Mol Biosci. 2018 Jun 4;5:50. doi: 10.3389/fmolb.2018.00050. eCollection 2018. Front Mol Biosci. 2018. PMID: 29951483 Free PMC article.
Cryo electron microscopy facilities running multiple instruments and serving users with varying skill levels need a robust and reliable method for benchmarking both the hardware and software components of their single particle analysis workflow. …
Cryo electron microscopy facilities running multiple instruments and serving users with varying skill levels need a robust and reliable meth …
Roodmus: a toolkit for benchmarking heterogeneous electron cryo-microscopy reconstructions.
Joosten M, Greer J, Parkhurst J, Burnley T, Jakobi AJ. Joosten M, et al. IUCrJ. 2024 Nov 1;11(Pt 6):951-965. doi: 10.1107/S2052252524009321. IUCrJ. 2024. PMID: 39404610 Free PMC article.
Conformational heterogeneity of biological macromolecules is a challenge in single-particle averaging (SPA). Current standard practice is to employ classification and filtering methods that may allow a discrete number of conformational states to be reconstructed. .. …
Conformational heterogeneity of biological macromolecules is a challenge in single-particle averaging (SPA). Current standard …
MicrographCleaner: A python package for cryo-EM micrograph cleaning using deep learning.
Sanchez-Garcia R, Segura J, Maluenda D, Sorzano COS, Carazo JM. Sanchez-Garcia R, et al. J Struct Biol. 2020 Jun 1;210(3):107498. doi: 10.1016/j.jsb.2020.107498. Epub 2020 Apr 7. J Struct Biol. 2020. PMID: 32276087 Free article.
Cryo-EM Single Particle Analysis workflows require tens of thousands of high-quality particle projections to unveil the three-dimensional structure of macromolecules. Conventional methods for automatic particle picking tend …
Cryo-EM Single Particle Analysis workflows require tens of thousands of high-quality particle …