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Hippocampal SPARC regulates depression-related behavior.
Campolongo M, Benedetti L, Podhajcer OL, Pitossi F, Depino AM. Campolongo M, et al. Genes Brain Behav. 2012 Nov;11(8):966-76. doi: 10.1111/j.1601-183X.2012.00848.x. Epub 2012 Sep 27. Genes Brain Behav. 2012. PMID: 22950524
Predictive Outcomes for HER2-enriched Cancer Using Growth and Metastasis Signatures Driven By SPARC.
Güttlein LN, Benedetti LG, Fresno C, Spallanzani RG, Mansilla SF, Rotondaro C, Raffo Iraolagoitia XL, Salvatierra E, Bravo AI, Fernández EA, Gottifredi V, Zwirner NW, Llera AS, Podhajcer OL. Güttlein LN, et al. Among authors: Benedetti LG. Mol Cancer Res. 2017 Mar;15(3):304-316. doi: 10.1158/1541-7786.MCR-16-0243-T. Epub 2016 Dec 28. Mol Cancer Res. 2017. PMID: 28031408 Free article.
SPARC endogenous level, rather than fibroblast-produced SPARC or stroma reorganization induced by SPARC, is responsible for melanoma cell growth.
Prada F, Benedetti LG, Bravo AI, Alvarez MJ, Carbone C, Podhajcer OL. Prada F, et al. Among authors: Benedetti LG. J Invest Dermatol. 2007 Nov;127(11):2618-28. doi: 10.1038/sj.jid.5700962. Epub 2007 Jul 12. J Invest Dermatol. 2007. PMID: 17625595 Free article.
SPARC promotes cathepsin B-mediated melanoma invasiveness through a collagen I/α2β1 integrin axis.
Girotti MR, Fernández M, López JA, Camafeita E, Fernández EA, Albar JP, Benedetti LG, Valacco MP, Brekken RA, Podhajcer OL, Llera AS. Girotti MR, et al. Among authors: Benedetti LG. J Invest Dermatol. 2011 Dec;131(12):2438-47. doi: 10.1038/jid.2011.239. Epub 2011 Aug 18. J Invest Dermatol. 2011. PMID: 21850018 Free article.
A tumor-stroma targeted oncolytic adenovirus replicated in human ovary cancer samples and inhibited growth of disseminated solid tumors in mice.
Lopez MV, Rivera AA, Viale DL, Benedetti L, Cuneo N, Kimball KJ, Wang M, Douglas JT, Zhu ZB, Bravo AI, Gidekel M, Alvarez RD, Curiel DT, Podhajcer OL. Lopez MV, et al. Mol Ther. 2012 Dec;20(12):2222-33. doi: 10.1038/mt.2012.147. Epub 2012 Sep 4. Mol Ther. 2012. PMID: 22948673 Free PMC article.
SPARC downregulation attenuates the profibrogenic response of hepatic stellate cells induced by TGF-β1 and PDGF.
Atorrasagasti C, Aquino JB, Hofman L, Alaniz L, Malvicini M, Garcia M, Benedetti L, Friedman SL, Podhajcer O, Mazzolini G. Atorrasagasti C, et al. Am J Physiol Gastrointest Liver Physiol. 2011 May;300(5):G739-48. doi: 10.1152/ajpgi.00316.2010. Epub 2011 Feb 10. Am J Physiol Gastrointest Liver Physiol. 2011. PMID: 21311029 Free PMC article.
Protein kinase C and cancer: what we know and what we do not.
Garg R, Benedetti LG, Abera MB, Wang H, Abba M, Kazanietz MG. Garg R, et al. Among authors: Benedetti LG. Oncogene. 2014 Nov 6;33(45):5225-37. doi: 10.1038/onc.2013.524. Epub 2013 Dec 16. Oncogene. 2014. PMID: 24336328 Free PMC article. Review.
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