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Unmasking the dynamic interplay between intestinal P-glycoprotein and CYP3A4.
Cummins CL, Jacobsen W, Benet LZ. Cummins CL, et al. Among authors: benet lz. J Pharmacol Exp Ther. 2002 Mar;300(3):1036-45. doi: 10.1124/jpet.300.3.1036. J Pharmacol Exp Ther. 2002. PMID: 11861813
Bioavailability of cyclosporine with concomitant rifampin administration is markedly less than predicted by hepatic enzyme induction.
Hebert MF, Roberts JP, Prueksaritanont T, Benet LZ. Hebert MF, et al. Among authors: benet lz. Clin Pharmacol Ther. 1992 Nov;52(5):453-7. doi: 10.1038/clpt.1992.171. Clin Pharmacol Ther. 1992. PMID: 1424418
Transport and metabolism of cyclosporine in isolated rat hepatocytes. The effects of lipids.
Prueksaritanont T, Koike M, Hoener BA, Benet LZ. Prueksaritanont T, et al. Among authors: benet lz. Biochem Pharmacol. 1992 May 8;43(9):1997-2006. doi: 10.1016/0006-2952(92)90643-w. Biochem Pharmacol. 1992. PMID: 1596287
Effects of sulfobromophthalein and ethacrynic acid on glyceryl trinitrate relaxation.
Lau DT, Benet LZ. Lau DT, et al. Among authors: benet lz. Biochem Pharmacol. 1992 May 28;43(10):2247-54. doi: 10.1016/0006-2952(92)90184-k. Biochem Pharmacol. 1992. PMID: 1599510
The interconversion of prednisone and prednisolone in human and rabbit organs in vitro is a function of tissue integrity.
Hale VG, Benet LZ. Hale VG, et al. Among authors: benet lz. Pharmacology. 1992;44(5):273-82. doi: 10.1159/000138930. Pharmacology. 1992. PMID: 1620723
In vitro enantioselective glucuronidation of fenoprofen.
Volland C, Benet LZ. Volland C, et al. Among authors: benet lz. Pharmacology. 1991;43(2):53-60. doi: 10.1159/000138828. Pharmacology. 1991. PMID: 1775510
Pharmacokinetics of nitroglycerin and its dinitrate metabolites over a thirtyfold range of oral doses.
Nakashima E, Rigod JF, Lin ET, Benet LZ. Nakashima E, et al. Among authors: benet lz. Clin Pharmacol Ther. 1990 May;47(5):592-8. doi: 10.1038/clpt.1990.80. Clin Pharmacol Ther. 1990. PMID: 2111749
Pharmacokinetics and pharmacodynamics of glyceryl trinitrate and its two dinitrate metabolites in conscious dogs.
Lee FW, Salmonson T, Metzler CH, Benet LZ. Lee FW, et al. Among authors: benet lz. J Pharmacol Exp Ther. 1990 Dec;255(3):1222-9. J Pharmacol Exp Ther. 1990. PMID: 2124621
Effect of esterase inhibition on the disposition of zomepirac glucuronide and its covalent binding to plasma proteins in the guinea pig.
Smith PC, McDonagh AF, Benet LZ. Smith PC, et al. Among authors: benet lz. J Pharmacol Exp Ther. 1990 Jan;252(1):218-24. J Pharmacol Exp Ther. 1990. PMID: 2299592
High-fat meals increase the clearance of cyclosporine.
Gupta SK, Benet LZ. Gupta SK, et al. Among authors: benet lz. Pharm Res. 1990 Jan;7(1):46-8. doi: 10.1023/a:1015831408425. Pharm Res. 1990. PMID: 2300535
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