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Transporter-enzyme interactions: implications for predicting drug-drug interactions from in vitro data.
Benet LZ, Cummins CL, Wu CY. Benet LZ, et al. Curr Drug Metab. 2003 Oct;4(5):393-8. doi: 10.2174/1389200033489389. Curr Drug Metab. 2003. PMID: 14529371 Review.
Effects of low-density lipoprotein and ethinyl estradiol on cyclosporine metabolism in isolated rat liver perfusions.
Prueksaritanont T, Hoener BA, Benet LZ. Prueksaritanont T, et al. Among authors: benet lz. Drug Metab Dispos. 1992 Jul-Aug;20(4):547-52. Drug Metab Dispos. 1992. PMID: 1356733
Bioavailability of cyclosporine with concomitant rifampin administration is markedly less than predicted by hepatic enzyme induction.
Hebert MF, Roberts JP, Prueksaritanont T, Benet LZ. Hebert MF, et al. Among authors: benet lz. Clin Pharmacol Ther. 1992 Nov;52(5):453-7. doi: 10.1038/clpt.1992.171. Clin Pharmacol Ther. 1992. PMID: 1424418
Acyl glucuronides revisited: is the glucuronidation process a toxification as well as a detoxification mechanism?
Spahn-Langguth H, Benet LZ. Spahn-Langguth H, et al. Among authors: benet lz. Drug Metab Rev. 1992;24(1):5-47. doi: 10.3109/03602539208996289. Drug Metab Rev. 1992. PMID: 1555494 Review. No abstract available.
Transport and metabolism of cyclosporine in isolated rat hepatocytes. The effects of lipids.
Prueksaritanont T, Koike M, Hoener BA, Benet LZ. Prueksaritanont T, et al. Among authors: benet lz. Biochem Pharmacol. 1992 May 8;43(9):1997-2006. doi: 10.1016/0006-2952(92)90643-w. Biochem Pharmacol. 1992. PMID: 1596287
Prednisolone and prednisone exhibit linear extraction in the perfused rabbit liver.
Hale VG, Benet LZ. Hale VG, et al. Among authors: benet lz. Drug Metab Dispos. 1991 Jan-Feb;19(1):87-93. Drug Metab Dispos. 1991. PMID: 1673428
Stereoselective disposition of ketoprofen in rats.
Iwakawa S, He XW, Hashimoto S, Volland C, Benet LZ, Lin ET. Iwakawa S, et al. Among authors: benet lz. Drug Metab Dispos. 1991 May-Jun;19(3):717-8. Drug Metab Dispos. 1991. PMID: 1680643 No abstract available.
Stereoselective disposition of carprofen, flunoxaprofen, and naproxen in rats.
Iwakawa S, Spahn H, Benet LZ, Lin ET. Iwakawa S, et al. Among authors: benet lz. Drug Metab Dispos. 1991 Sep-Oct;19(5):853-7. Drug Metab Dispos. 1991. PMID: 1686227
Stereoselective degradation of the fenoprofen acyl glucuronide enantiomers and irreversible binding to plasma protein.
Volland C, Sun H, Dammeyer J, Benet LZ. Volland C, et al. Among authors: benet lz. Drug Metab Dispos. 1991 Nov-Dec;19(6):1080-6. Drug Metab Dispos. 1991. PMID: 1687014
Nitroglycerin metabolism in subcellular fractions of rabbit liver. Dose dependency of glyceryl dinitrate formation and possible involvement of multiple isozymes of glutathione S-transferases.
Lau DT, Benet LZ. Lau DT, et al. Among authors: benet lz. Drug Metab Dispos. 1990 May-Jun;18(3):292-7. Drug Metab Dispos. 1990. PMID: 1974188
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