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Impact of the Potential Antitumor Agent 2-(4-Hydroxyphenyl) Amino-1,4-Naphthoquinone (Q7) on Vasomotion Is Mediated by the Vascular Endothelium, But Not Vascular Smooth Muscle Cell Metabolism.
Palacios J, Benites J, Owen GI, Morales P, Chiong M, Nwokocha CR, Paredes A, Cifuentes F. Palacios J, et al. Among authors: benites j. J Cardiovasc Pharmacol. 2021 Feb 1;77(2):245-252. doi: 10.1097/FJC.0000000000000940. J Cardiovasc Pharmacol. 2021. PMID: 33105322
Modulatory Effect of 2-(4-Hydroxyphenyl)amino-1,4-naphthoquinone on Endothelial Vasodilation in Rat Aorta.
Palacios J, Cifuentes F, Valderrama JA, Benites J, Ríos D, González C, Chiong M, Cartes-Saavedra B, Lafourcade C, Wyneken U, González P, Owen GI, Pardo F, Sobrevia L, Buc Calderon P. Palacios J, et al. Among authors: benites j. Oxid Med Cell Longev. 2016;2016:3939540. doi: 10.1155/2016/3939540. Epub 2016 Sep 8. Oxid Med Cell Longev. 2016. PMID: 27672420 Free PMC article.
Ascorbate Attenuates Oxidative Stress and Increased Blood Pressure Induced by 2-(4-Hydroxyphenyl) Amino-1,4-naphthoquinone in Rats.
Palacios J, Fonseca JM, Ayavire F, Salas F, Ortiz M, Sandoval JM, Benites J, Nwokocha CR, Zavala E, Paredes A, Barría I, Vega JL, Cifuentes F. Palacios J, et al. Among authors: benites j. Oxid Med Cell Longev. 2018 Jul 26;2018:8989676. doi: 10.1155/2018/8989676. eCollection 2018. Oxid Med Cell Longev. 2018. PMID: 30147836 Free PMC article.
Substituted 3‑acyl‑2‑phenylamino‑1,4‑naphthoquinones intercalate into DNA and cause genotoxicity through the increased generation of reactive oxygen species culminating in cell death.
Farias MS, Pich CT, Kviecinski MR, Bucker NC, Felipe KB, Da Silva FO, Günther TM, Correia JF, Ríos D, Benites J, Valderrama JA, Calderon PB, Pedrosa RC. Farias MS, et al. Among authors: benites j. Mol Med Rep. 2014 Jul;10(1):405-10. doi: 10.3892/mmr.2014.2160. Epub 2014 Apr 16. Mol Med Rep. 2014. PMID: 24756411
In vivo inhibition of tumor progression by 5 hydroxy-1,4-naphthoquinone (juglone) and 2-(4-hydroxyanilino)-1,4-naphthoquinone (Q7) in combination with ascorbate.
Ourique F, Kviecinski MR, Zirbel G, Castro LSEPW, Gomes Castro AJ, Mena Barreto Silva FR, Valderrama JA, Rios D, Benites J, Calderon PB, Pedrosa RC. Ourique F, et al. Among authors: benites j. Biochem Biophys Res Commun. 2016 Sep 2;477(4):640-646. doi: 10.1016/j.bbrc.2016.06.113. Epub 2016 Jun 24. Biochem Biophys Res Commun. 2016. PMID: 27346131 Free article.
45 results